JM Fuller, AE Kwitek, TJ Hawkins, DH … - Diabetes, 2006 - Am Diabetes Assoc Failure to express the Gimap5 protein is associated with lymphopenia (lyp) and
linked to spontaneous diabetes in the diabetes-prone BioBreeding (BBDP) rat.
Gimap5 is a member of seven related genes located within 150 Kb on rat ... Cited by 6 - Related articles - BL Direct - All 5 versions
T Hawkins, J Fuller, K Olson, S Speros, Å … - Journal of Autoimmunity, 2005 - Elsevier In two independent series of transplants, all DR. lyp /lyp rats (n = 5 and 4)
receiving DR. lyp /lyp bone marrow retained lymphopenia and developed insulitis
(5/5 and 4/4) as well as diabetes in some (2/5 and 3/4). Both DR. +/+ and ... Cited by 5 - Related articles - All 3 versions
JJ Filen, S Filen, R Moulder, S Tuomela, H … - Molecular & Cellular Proteomics, 2009 - ASBMB T helper (Th) cells differentiate into functionally distinct effector cell
subsets of which Th1 and Th2 cells are best characterized. Besides T cell
receptor signaling, IL-12-induced STAT4 and T-bet- and IL-4-induced STAT6 ... Cited by 2 - Related articles - All 4 versions
- ►diabetesjournals.org RH Wallis, KS Wang, D Dabrowski, L Marandi, … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—The biobreeding diabetes-prone (BBDP) rat spontaneously develops
type 1 diabetes. Two of the genetic factors contributing to this syndrome are
the major histocompatibility complex (Iddm1) and a Gimap5 mutation (Iddm2) ... Cited by 2 - Related articles - BL Direct - All 7 versions
G Garruti, G De Pergola, M Cignarelli, M Stock … - Minerva endocrinologica - ncbi.nlm.nih.gov Some sympathomimetic compounds (ie BRL37344) increase brown adipose tissue (BAT)
thermogenesis with minimal cardiac effects. They act through an "atypical"
beta-adrenergic receptor (beta-AR). Since beta-AR responses involve ... Cited by 2 - Related articles
S Ilangumaran, M Forand-Boulerice, SM … - Molecular Immunology, 2009 - Elsevier The recessive lyp allele, which harbors a defective gimap5 (GTPase of
immunity-associated nucleotide binding protein 5) gene, causes spontaneous
apoptosis of T lymphocytes in the biobreeding diabetes-prone strain of ... Cited by 2 - Related articles - All 2 versions
JP Mordes, L Cort, E Norowski, J Leif, JM … - Mammalian Genome, 2009 - Springer Abstract Iddm14 (formerly Iddm4) is a non-MHC-linked genetic locus associated
with autoimmune diabetes. Its effects have been well-documented in BB-derived
rats in which diabetes is either induced by immunologic perturba- tion or ... Cited by 4 - Related articles - All 2 versions
M Stienekemeier, K Hofmann, R Gold, T … - Immunogenetics, 2000 - Springer Page 1. Immunogenetics (2000) 51:296–305 Q Springer-Verlag 2000 ORIGINAL PAPER Martina
Stienekemeier 7 Kathrin Hofmann Ralf Gold 7 Thomas Herrmann ... Cited by 4 - Related articles - All 2 versions
EP Blankenhorn, C DeScipio, L Rodemich, L … - Ann NY Acad Sci, 2007 - interscience.wiley.com Abstract : Iddm4 is a dominant non-major histocompatibility complex (MHC)
determinant of diabetes susceptibility in BBDR rats treated with poly I:C, plus
depletion of regulatory T cells. In congenic MHC-identical normal WF rats, ... Cited by 4 - Related articles - BL Direct - All 6 versions
- ►hematologylibrary.org RD Schulteis, H Chu, X Dai, Y Chen, B … - Blood, 2008 - bloodjournal.hematologylibrary.org The loss of Gimap5 (GTPase of the immune-associated protein 5) gene function is
the underlying cause of lymphopenia and autoimmune diabetes in the BioBreeding
(BB) rat. The in vivo function of murine gimap5 is largely unknown. We show ... Cited by 6 - Related articles - All 3 versions
