G Placha, GD Poznik, J Dunn, A Smiles, B … - Diabetes, 2006 - Am Diabetes Assoc We performed a variance components linkage analysis of renal function, measured
as glomerular filtration rate (GFR), in 63 extended families with multiple
members with type 2 diabetes. GFR was estimated from serum concentrations ... Cited by 30 - Related articles - BL Direct - All 5 versions
- ►ajkd.org G Chen, AA Adeyemo, J Zhou, Y Chen, A … - American Journal of Kidney Diseases, 2007 - Elsevier Reduced renal function often is a major consequence of diabetes and
hypertension. Although several indices of renal function (eg, creatinine
clearance) are clearly heritable and show linkage to several genomic ... Cited by 19 - Related articles - All 7 versions
JD Center, AS Krolewski… - Kidney international, 2006 - mhp.koshigaya.saitama.jp Nominal P-values foe evidence for linkage in all relatives on 22 q, 5q and 7q
were lower than empirical, indicating that the nominal P-values may have
slightly overstated the evidence for linkage to these regions. In contrast, ... Cited by 42 - Related articles - BL Direct - All 4 versions
- ►asnjournals.org CS Fox, Q Yang, LA Cupples, CY Guo, MG … - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol ABSTRACT. Kidney disease is a risk factor for the development of cardiovascular
disease, all-cause mortality, and ESRD. It is not known to what extent genetic
factors play a role in the development of kidney disease in the general ... Cited by 44 - Related articles - BL Direct - All 5 versions
SC Hunt, H Coon, SJ Hasstedt, RM Cawthon, … - American journal of hypertension, 2004 - Elsevier Serum creatinine and creatinine clearance are used as indicators of renal
function and may indicate a propensity for development of end-stage renal
disease. Identifying genes related to future decreases in renal function ... Cited by 26 - Related articles - All 4 versions
- ►oxfordjournals.org JM Leon, BI Freedman, MB Miller, KE North, … - Nephrology Dialysis Transplantation, 2007 - ERA-EDTA Results. The phenotypic correlation between ACR and GFR was not significant in
EAs (r = 0.04) and significantly negative in AAs (r = –0.17). Univariate
analyses of ACR showed suggestive evidence of linkage on chromosomes 8, 16 ... Cited by 18 - Related articles - BL Direct - All 4 versions
CD Langefeld, SR Beck, DW Bowden, SS … - American journal of kidney diseases, 2004 - Elsevier Elevated urinary albumin excretion and decreased glomerular filtration rate
(GFR) are risk factors for cardiovascular death and end-stage renal disease in
individuals with type 2 diabetes mellitus (DM). To determine the extent of ... Cited by 38 - Related articles - BL Direct - All 11 versions
AM Osterholm, B He, J Pitkaniemi, L Albinsson … - Kidney International, 2006 - nature.com Diabetic nephropathy (DN) is the primary cause of morbidity and mortality in
patients with type 1 as well as type 2 diabetes, and accounts for 40% of
end-stage renal disease in the Western world. Familial clustering of DN ... Cited by 33 - Related articles - BL Direct - All 5 versions
BI Freedman, DW Bowden, SS Rich, CJ Valis, … - Nephrology Dialysis Transplantation, 2005 - ERA-EDTA Results. NPL regression provided modest evidence of linkage to 13q33.3 near
D13S796 [log of the odds (LOD) = 1.72], 9q34.3 near D9S1826 (LOD = 1.22),
4p15.32 near D4S2639 (LOD = 1.11) and 1q25.1 near D1S1589 (LOD = 1.01). ... Cited by 25 - Related articles - All 6 versions
SK Iyengar, HE Abboud, KAB Goddard, MF Saad … - Diabetes, 2007 - Am Diabetes Assoc The Family Investigation of Nephropathy and Diabetes (FIND) was initiated to map
genes underlying susceptibility to diabetic nephropathy. A total of 11 centers
participated under a single collection protocol to recruit large numbers of ... Cited by 37 - Related articles - BL Direct - All 8 versions
