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Sodium-coupled glucose cotransporters contribute to hypothalamic glucose sensing

- diabetesjournals.org
DO'Malley, F Reimann, AK Simpson, FM Gribble - Diabetes, 2006 - Am Diabetes Assoc
Specialized neurons within the hypothalamus have the ability to sense and
respond to changes in ambient glucose concentrations. We investigated the
mechanisms underlying glucose-triggered activity in glucose-excited ...
Cited by 4 - Related articles - BL Direct - All 8 versions

Glutamate receptors modulate sodium-dependent and calcium-independent vitamin C …


CC Portugal, VS Miya, K da Costa Calaza, … - System, 1927 - interscience.wiley.com
Vitamin C is transported in the brain by sodium vitamin C co-transporter 2
(SVCT-2) for ascorbate and glucose transporters for dehydroascorbate. Here we
have studied the expression of SVCT-2 and the uptake and release of [ 14 C] ...
Cited by 1 - Related articles - All 4 versions

Regulation of Glucose Transporter 3 Surface Expression by the AMP-Activated Protein …

- jneurosci.org
P Weisova, CG Concannon, M Devocelle, … - Journal of Neuroscience, 2009 - Soc Neuroscience
Ischemic and excitotoxic events within the brain result in rapid and often
unfavorable depletions in neuronal energy levels. Here, we investigated the
signaling pathways activated in response to the energetic stress created by ...
Cited by 1 - Related articles - All 4 versions

The free fatty acid metabolome in cerebral ischemia following human mesenchymal stem cell …


MJ Paik, WY Li, YH Ahn, PH Lee, S Choi, KR … - Clinica Chimica Acta, 2009 - Elsevier
Rats were subjected to 2-hours MCAo, followed by intravenous transplantation of
hMSC or phosphate-buffered saline (PBS) at one day after MCAo. All rats were
sacrificed 5 days after MCAo. Metabolic profiling of free fatty acids ...
Cited by 1 - Related articles - All 2 versions

A Functional Role for Sodium-Dependent Glucose Transport across the Blood-Brain Barrier …


S Vemula, KE Roder, T Yang, GJ Bhat, TJ … - Journal of Pharmacology and Experimental …, 2009 - ASPET
In the current study, we determined the functional significance of
sodium-dependent/-independent glucose transporters at the neurovasculature
during oxygen glucose deprivation (OGD). Confluent brain endothelial cells ...
Cited by 1 - Related articles - All 3 versions

Dissociation between sensing and metabolism of glucose in sugar sensing neurones


JA Gonzalez, F Reimann, D Burdakov - The Journal of Physiology, 2009 - Physiological Soc
Some of the neurones controlling sleep, appetite and hormone release act as
specialized detectors of ambient glucose. Their sugar sensing is conventionally
thought to involve glucokinase-dependent metabolism of glucose to ATP, ...
Cited by 8 - Related articles - All 5 versions

[CITATION] Paes-de-Carvalho R (2009) Glutamate receptors modulate sodium-dependent and calcium- …


CC Portugal, VS Miya, C Calaza Kda, RA … - J. Neurochem
Cited by 2 - Related articles

Ascorbic acid participates in a general mechanism for concerted glucose transport inhibition …


MA Castro, C Angulo, S Brauchi, F Nualart, II … - Pflügers Archiv European Journal of Physiology, 2008 - Springer
Abstract In this paper, we present a novel function for ascorbic acid. Ascorbic
acid is an important water-soluble antioxidant and cofactor in various enzyme
systems. We have previously demonstrated that an increase in neuronal ...
Cited by 3 - Related articles - All 2 versions

Molecular identification and functional characterization of the vitamin C transporters …


C Angulo, MA Castro, CI Rivas, D Segretain, … - Journal of Cellular Physiology, 2008 - interscience.wiley.com
Vitamin C is an essential micronutrient for the development of male germ cells.
In the gonad, the germ cells are isolated from the systemic circulation by the
blood-testis barrier, which consists of a basal layer of Sertoli cells that ...
Cited by 2 - Related articles - All 3 versions

Brain energetics (thought needs food)


L Pellerin - Current Opinion in Clinical Nutrition & Metabolic Care, 2008 - journals.lww.com
Introduction For a long time, glucose was thought to be the exclusive energy
substrate for brain cells, and its complete oxi- dation within each cell
represented the sole relevant metabolic process to fuel brain activity. ...
Cited by 2 - Related articles - All 4 versions


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