- ►diabetesjournals.org JC Henquin, D Dufrane, M Nenquin - Diabetes, 2006 - Am Diabetes Assoc Pancreatic islets were isolated from 16 nondiabetic organ donors and, after
culture for ∼2 days in 5 mmol/l glucose, were perifused to characterize
nutrient-induced insulin secretion in human islets. Stepwise increases from ... Cited by 16 - Related articles - BL Direct - All 5 versions
M Braun, R Ramracheya, M Bengtsson, Q … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Human β-cells express two types of voltage-gated K + currents that
flow through delayed rectifying (K V 2.1/2.2) and large-conductance Ca 2+
-activated K + (BK) channels. Blockade of BK channels (using iberiotoxin) ... Cited by 14 - Related articles - All 5 versions
- ►physiology.org N Ishiyama, MA Ravier, JC Henquin - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc Glucose induces insulin secretion (IS) and also potentiates the
insulin-releasing action of secretagogues such as arginine and sulfonylureas.
This potentiating effect is known to be impaired in type 2 diabetic ... Cited by 11 - Related articles - BL Direct - All 4 versions
D Dufrane, M Nenquin, JC Henquin - Diabetes and Metabolism, 2007 - Elsevier Increasing glucose from 1 to 15 mM weakly (~ 2×) stimulated insulin secretion,
which was potentiated (~ 12×) by the cAMP-producing agent, forskolin. The
effect of glucose was concentration-dependent (threshold at 3 –5 mM and ... Cited by 6 - Related articles - BL Direct - All 2 versions
- ►physiology.org R Cruz-Cruz, A Salgado, C Sanchez-Soto, L … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc Glucose-induced insulin secretion by pancreatic -cells depends on membrane
depolarization and [Ca 2+ ] i increase. We correlated voltage- and current-clamp
recordings, [Ca 2+ ] i measurements, and insulin reverse hemolytic plaque ... Cited by 7 - Related articles - BL Direct - All 4 versions
- ►nih.gov J Herrington, M Sanchez, D Wunderler, L Yan … - The Journal of Physiology, 2005 - Physiological Soc Voltage-gated potassium (Kv) currents of human pancreatic islet cells were
studied by whole-cell patch clamp recording. On average, 75% of the cells tested
were identified as β-cells by single cell, post-recording RT-PCR for ... Cited by 10 - Related articles - BL Direct - All 8 versions
- ►endojournals.org [PDF] MA Ravier, M Nenquin, T Miki, S Seino, JC … - Endocrinology, 2008 - Endocrine Soc Page 1. 1 Glucose controls cytosolic Ca 2+ and insulin secretion in mouse islets
lacking ATP-sensitive K + channels owing to a knockout of the pore-forming ... Cited by 2 - Related articles
[CITATION] Electrophysiology of the-cell and mechanisms of inhibition of insulin release
MJ Dunne, C Ammälä, SG Straub, GWG … - Handbook of Physiology. The Endocrine System. The … Cited by 3 - Related articles
M Hiriart, L Aguilar-Bryan - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Mammalian β-cells are acutely and chronically regulated by sensing surrounding
glucose levels that determine the rate at which insulin is secreted, to maintain
euglycemia. Experimental research in vitro and in vivo has shown that, when ... Cited by 3 - Related articles - All 3 versions
- ►jbc.org P Stiernet, Y Guiot, P Gilon, JC Henquin - Journal of Biological Chemistry, 2006 - ASBMB Glucose-induced insulin secretion requires a rise in -cell cytosolic Ca 2+ ([Ca
2+ ] c ) that triggers exocytosis and a mechanistically unexplained
amplification of the action of [Ca 2+ ] c . Insulin granules are kept ... Cited by 14 - Related articles - BL Direct - All 6 versions
