- ►diabetesjournals.org L Rachdi, N Balcazar, L Elghazi, DJ Barker, I Krits, H … - Diabetes, 2006 - Am Diabetes Assoc The steps controlling entry and progression through G 1 are dependent on cell type and
context. Little is known about the cell cycle in β-cells, but recent work from several laboratories
has shown that cyclin-dependent kinase-4 (cdk4) and cyclins D1 and D2 are critical ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org I Cozar-Castellano, M Haught, AF Stewart - Diabetes, 2006 - Am Diabetes Assoc The rate of pancreatic β-cell replication is extremely slow. For example, Finegood et al. (1) report
that 3% of rodent β-cells replicate every 24 h. Kushner and colleagues (2) have recently reported
that in older mice, this rate is even slower, in the range of 0.07% of β-cells per 24 h. Butler ... Cited by 11 - Related articles - BL Direct - All 5 versions
I Cozar-Castellano, M Weinstock, M Haught… - Diabetes, 2006 - ncbi.nlm.nih.gov We hypothesized that combined transgenic overexpression of hepatocyte growth factor
(HGF) and placental lactogen in islets would lead to even greater increases in beta-cell mass
and replication than either growth factor alone. This did not occur, suggesting that ... Cited by 22 - Related articles - BL Direct - All 2 versions
[CITATION] b-Cell-Targeted Expression of a Dominant-Negative Hepatocyte Nuclear Factor-1a …
… -Johansson, PL Herrera, H Wang, A … - …, 2001 - … for the Endocrine Society by JB … Cited by 11 - Related articles
- ►diabetesjournals.org RC Vasavada, I Cozar-Castellano, D Sipula, AF … - Diabetes, 2007 - Am Diabetes Assoc Animal studies show that G 1/S regulatory molecules (D-cyclins, cdk-4, p18, p21, p27) are critical
for normal regulation of β-cell proliferation, mass, and function. The retinoblastoma protein,
pRb, is positioned at the very end of a cascade of these regulatory proteins and is ... Cited by 12 - Related articles - BL Direct - All 5 versions
Y Zhu, B King, B Parvizi, B Brunk, C Stoeckert, J … - Genome …, 2003 - genomebiology.com The volume and diversity of expressed sequence tag (EST) data in the public databases makes
them an important resource for gene identification, genome annotation and comparative
genomics. The value of EST data is enhanced when the sequences are clustered (on the ... Cited by 12 - Related articles - Cached - All 17 versions
- ►nih.gov [PDF] JH Lichy, M Majidi, J Elbaum, MM Tsai - Nucleic acids research, 1996 - Oxford Univ Press 1 Department of Cellular Pathology, Armed Forces Institute of Pathology, Washington, DC
20306-6000, USA and 2 Laboratory of Tumor Virus Biology, National Cancer Institute,
Bethesda, MD 20892, USA ... Received August 19, 1996; Revised and Accepted ... Cited by 13 - Related articles - BL Direct - All 6 versions
- ►jbc.org M Majidi, AE Hubbs, JH Lichy - Journal of Biological Chemistry, 1998 - ASBMB The human ST5 gene encodes three proteins with predicted molecular masses of 126, 82, and
70 kDa. These widely expressed proteins share a C-terminal region that bears significant sequence
homology to a group of GDP/GTP exchange proteins for the Rab3 family of small GTP ... Cited by 16 - Related articles - BL Direct - All 4 versions
[CITATION] Hepatocyte nuclear factor 4 regulates the expression of pancreatic-cell genes …
- ►endojournals.org I Cozar-Castellano, N Fiaschi-Taesch, TA Bigatel, … - Endocrine reviews, 2006 - Endocrine Soc Type 1 and type 2 diabetes both result from inadequate production of insulin by the ß-cells of
the pancreatic islet. Accordingly, strategies that lead to increased pancreatic ß-cell mass, as
well as retained or enhanced function of islets, would be desirable for the treatment of ... Cited by 54 - Related articles - BL Direct - All 5 versions
