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Scholar Results 1 - 10 of about 101 related to Ivakine: The idd4 locus displays sex-specific epistatic effects on type 1 diabetes susceptibility.... (0.09 sec) 

The idd4 locus displays sex-specific epistatic effects on type 1 diabetes susceptibility in …

- shouxi.net
EA Ivakine, SM Mortin-Toth, OM Gulban, A … - Diabetes, 2006 - Am Diabetes Assoc
The nonobese diabetic (NOD) mouse recapitulates many aspects of the pathogenesis
of type 1 diabetes in humans, including inheritance as a complex trait. More
than 20 Idd loci have been linked to type 1 diabetes susceptibility in NOD ...
Cited by 6 - Related articles - BL Direct - All 5 versions

Molecular genetic analysis of the Idd4 locus implicates the IFN response in type 1 diabetes …

- jimmunol.org
EA Ivakine, OM Gulban, SM Mortin-Toth, E … - The Journal of Immunology, 2006 - Am Assoc Immnol
High-resolution mapping and identification of the genes responsible for type 1
diabetes (T1D) has proved difficult because of the multigenic etiology and low
penetrance of the disease phenotype in linkage studies. Mouse congenic ...
Cited by 9 - Related articles - BL Direct - All 6 versions

Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are …


M McDuffie, NA Maybee, SR Keller, BK … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE— 12/15-lipoxygenase (12/15-LO), one of a family of fatty acid
oxidoreductase enzymes, reacts with polyenoic fatty acids to produce
proinflammatory lipids. 12/15-LO is expressed in macrophages and pancreatic ...
Cited by 6 - Related articles - BL Direct - All 5 versions

Nordihydroguaiaretic acid induces astroglial death via glutathione depletion


JY Im, PL Han - Journal of neuroscience research, 2007 - interscience.wiley.com
Nordihydroguaiaretic acid (NDGA) is known to cause cell death in certain cell
types that is independent of its activity as a lipoxygenase inhibitor; however,
the underlying mechanisms are not fully understood. In the present study, ...
Cited by 2 - Related articles - BL Direct - All 3 versions

Monochloramine potently inhibits arachidonic acid metabolism in rat platelets

- vce.org [PDF] 
Y Fujimoto, M Ikeda, S Sakuma - Biochemical and Biophysical Research …, 2006 - Elsevier
In the present study, the effects of hypochlorous acid (HOCl), monochloramine
(NH 2 Cl), glutamine-chloramine (Glu-Cl) and taurine-chloramine (Tau-Cl) on the
formation of 12-lipoxygenase (LOX) metabolite, 12-HETE, and cyclooxygenase ...
Cited by 2 - Related articles - All 6 versions

[CITATION] voodi-Semiromi A, Kumar GP, McDuffie M, She JX: Impaired Crkl expression contributes to …


M Laloraya - Diabetes, 2006
Cited by 2 - Related articles

[CITATION] The Jackson Laboratory


EH Leiter
Cited by 2 - Related articles

[CITATION] mron-Boles D, Husain Z, Dredge R, Daly MJ, Ingalls KA, O'Connor TJ: A comprehensive …


WF Dietrich, J Miller, R Steen, MA Merchant - Nature, 1996
Cited by 4 - Related articles

Cellular and molecular mechanisms of the selective regulation of IL-12 production by 12/15 …

- jimmunol.org
MK Middleton, T Rubinstein, E Pure - The Journal of Immunology, 2006 - Am Assoc Immnol
IL-12 drives type I immune responses and can mediate chronic inflammation that
leads to host defense as well as disease. Recently, we discovered a novel role
for 12/15-lipoxygenase (12/15-LO) in mediating IL-12p40 expression in ...
Cited by 15 - Related articles - BL Direct - All 3 versions

Sex-specific differences in chromosome-dependent regulation of vascular reactivity in …

- physiology.org
MP Kunert, MR Dwinell, I Drenjancevic Peric … - … Journal of Physiology- Regulatory, Integrative and …, 2008 - Am Physiological Soc
High-throughput studies in the Medical College of Wisconsin Program for Genomic
Applications (Physgen) were designed to link chromosomes with physiological
function in consomic strains derived from a cross between Dahl ...
Related articles - All 5 versions


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