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Scholar Results 1 - 10 of about 101 related to Taneera: Failure of transplanted bone marrow cells to adopt a pancreatic β-cell fate. (0.15 sec) 

Failure of transplanted bone marrow cells to adopt a pancreatic β-cell fate


J Taneera, A Rosengren, E Renstrom, JM Nygren, P … - Diabetes, 2006 - Am Diabetes Assoc
Recent studies in normal mice have suggested that transplanted bone marrow cells can transdifferentiate
into pancreatic β-cells at relatively high efficiency. Herein, adopting the same and alternative
approaches to deliver and fate map-transplanted bone marrow cells in the pancreas of ...
Cited by 48 - Related articles - BL Direct - All 5 versions

No evidence for significant transdifferentiation of bone marrow into pancreatic β- …

- diabetesjournals.org
A Lechner, YG Yang, RA Blacken, L Wang, AL Nolan, … - Diabetes, 2004 - Am Diabetes Assoc
Several recent studies have suggested that the adult bone marrow harbors cells that can differentiate
into tissues from all three germ layers. Other reports have contradicted these findings or attributed
them to cell fusion. In this study, we investigated whether bone marrow−derived cells ...
Cited by 114 - Related articles - BL Direct - All 4 versions

Little evidence of transdifferentiation of bone marrow-derived cells into pancreatic …


JB Choi, H Uchino, K Azuma, N Iwashita, Y Tanaka, H … - Diabetologia, 2003 - Springer
Aims/hypothesis. Bone marrow cells contain at least two distinct types of stem cells which are
haemato- poietic stem cells and mesenchymal stem cells. Both cells have the ability to differentiate
into a variety of cell types derived from all three germ layers. Thus, bone marrow stem ...
Cited by 134 - Related articles - BL Direct - All 3 versions

Reversal of experimental diabetes by multiple bone marrow transplantation


M Banerjee, A Kumar, RR Bhonde - Biochemical and Biophysical Research …, 2005 - Elsevier
Therapeutic utility of bone marrow transplantation in diabetic patients to overcome deficient
β-cell population is an attractive proposal. However, the status of bone marrow stem cells
(BMSCs) under hyperglycemia is not known. In the present study, we investigated the ...
Cited by 43 - Related articles - All 5 versions

Recruitment of bone marrow-derived endothelial cells to sites of pancreatic β-cell …


V Mathews, PT Hanson, E Ford, J Fujita, KS Polonsky, … - Diabetes, 2004 - Am Diabetes Assoc
Endothelial progenitor cells (EPCs) are detectable in the blood and bone marrow throughout
life. These cells contribute to new blood vessel formation (neovascularization) in physiological
states such as wound healing and in pathological states such as tumor angiogenesis. We ...
Cited by 117 - Related articles - BL Direct - All 4 versions

Human bone marrow mesenchymal stem cells can express insulin and key …

- alphamedpress.org
C Moriscot, F de Fraipont, MJ Richard, M Marchand, P … - Stem Cells, 2005 - AlphaMed Press
Multipotential stem cells can be selected from the bone marrow by plastic adhesion,
expanded, and cultured. They are able to differentiate not only into multiple cell types, including
cartilage, bone, adipose and fibrous tissues, and myelosupportive stroma, but also into ...
Cited by 114 - Related articles - All 7 versions

Multipotent stromal cells from human marrow home to and promote repair of …

- pnas.org
RH Lee, MJ Seo, RL Reger, JL Spees, … - Proceedings of the …, 2006 - National Acad Sciences
We tested the hypothesis that multipotent stromal cells from human bone marrow (hMSCs) can
provide a potential therapy for human diabetes mellitus. Severe but nonlethal hyperglycemia
was produced in NOD/scid mice with daily low doses of streptozotocin on days 1–4, and ...
Cited by 108 - Related articles - BL Direct - All 14 versions

Bone Marrow (BM) Transplantation Promotes {beta}-Cell Regeneration after Acute …

- endojournals.org
Y Hasegawa, T Ogihara, T Yamada, Y Ishigaki, J Imai, … - Endocrinology, 2007 - Endocrine Soc
There is controversy regarding the roles of bone marrow (BM)-derived cells in pancreatic ß-cell
regeneration. To examine these roles in vivo, mice were treated with streptozotocin (STZ), followed
by bone marrow transplantation (BMT; lethal irradiation and subsequent BM cell infusion) ...
Cited by 27 - Related articles - BL Direct - All 4 versions

In vivo and in vitro characterization of insulin-producing cells obtained from murine …


DQ Tang, LZ Cao, BR Burkhardt, CQ Xia, SA Litherland … - Diabetes, 2004 - Am Diabetes Assoc
Efforts toward routine islet cell transplantation as a means for reversing type 1 diabetes have
been hampered by islet availability as well as allograft rejection. In vitro transdifferentiation of
mouse bone marrow (BM)-derived stem (mBMDS) cells into insulin-producing cells could ...
Cited by 214 - Related articles - BL Direct - All 7 versions

Adult bone marrow-derived cells trans-differentiating into insulin-producing cells for …


SH Oh, TM Muzzonigro, SH Bae, JM LaPlante, HM … - Laboratory …, 2004 - nature.com
Recent findings suggest that bone marrow (BM) cells have the capacity to differentiate into a
variety of cell types including endocrine cells of the pancreas. We report that BM derived
cells, when cultured under defined conditions, were induced to trans-differentiate into ...
Cited by 146 - Related articles - BL Direct - All 5 versions


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