GGM Pinkse, WP Bouwman, R Jiawan-Lalai, OT … - Diabetes, 2006 - Am Diabetes Assoc Islet transplantation is associated with a high rate of early graft failure caused by early immune
attack and poor functionality of islets. Apoptosis of islet cells appears soon after islet isolation
and primarily involves the β-cell. The purpose of this study was to determine the effect of ... Cited by 24 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org G Parnaud, E Hammar, DG Rouiller, M Armanet, PA … - Diabetes, 2006 - Am Diabetes Assoc When attached on a matrix produced by a rat bladder carcinoma cell line (804G matrix), rat pancreatic
β-cells spread in response to glucose and secrete more insulin compared with cells attached
on poly-l-lysine. The aim of this study was to determine whether laminin-5 and its ... Cited by 22 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org R Wang, J Li, K Lyte, NK Yashpal, F Fellows, CG … - Diabetes, 2005 - Am Diabetes Assoc The integrin receptors play a major role in tissue morphogenesis and homeostasis by regulating
cell interactions with extracellular matrix proteins. We have examined the expression pattern
of integrin subunits in the human fetal pancreas (8–20 weeks fetal age) and the relevance ... Cited by 23 - Related articles - All 4 versions
KS Masters, KS Anseth - Advances in Chemical Engineering, 2004 - 万方数据资源系统 The nature of cell adhesion to substrate materials has a tremendous effect on cell function and
tissue development. Signaling cascades initiated by cell adhesion have the ability to regulate
a variety of events, including embryogenesis, tissue differentiation, and cell migration ( ... Cited by 4 - Related articles - BL Direct
N Nagata, A Iwanaga, K Inoue, Y … - Journal of Biomaterials …, 2002 - ingentaconnect.com Abstract—The purpose of this study was to investigatethe effect of culture microenvironmenton
the cell death of isolated rat pancreatic islets. After isolation by the conventional collagenase
digestion technique, the islets were cultured in a hydrogel of collagen type I mixed with ... Cited by 14 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org [PDF] RN Wang, L Rosenberg - Journal of Endocrinology, 1999 - Soc Endocrinology Islet transplantation is associated with a high rate of early graft failure, a problem that remains
poorly understood. It is probable that the destruction of the islet microenviron- ment and loss
of tropic support that occur during isolation lead to compromised survival. The purpose of ... Cited by 83 - Related articles - BL Direct - All 6 versions
R Perfetti, TE Henderson, Y Wang, C Montrose- … - Pancreas, 1996 - journals.lww.com Summary: Primary culture of rat islets of Langerhans lose glucose responsiveness and eventually
die when cul- tured for a long period of time. In this study we evaluated the effect of matrigel,
a basement membrane extract, on (i) islet cell survival, (ii) cell responsiveness following a ... Cited by 16 - Related articles - BL Direct - All 3 versions
T Kaido, M Yebra, V Cirulli, AM Montgomery - Journal of Biological Chemistry, 2004 - ASBMB Collagens have been shown to influence the survival and function of cultured -cells;
however, the utilization and function of individual collagen receptors in -cells is largely
unknown. The integrin superfamily contains up to five collagen receptors, but we have ... Cited by 32 - Related articles - All 4 versions
K Edamura, K Nasu, Y Iwami, H Ogawa, N Sasaki, … - Cell …, 2003 - ncbi.nlm.nih.gov The effect of either adhesion or collagen molecules on cell attachment, insulin secretion, and
glucose responsiveness was investigated in adult porcine pancreatic endocrine (PE) cells that
were cultured for a longer term in vitro. Six different types of molecules--laminin, ... Cited by 17 - Related articles - BL Direct
NK Yashpal, J Li, MB Wheeler, R Wang - Endocrinology, 2005 - Endocrine Soc The integrin receptors link to extracellular matrix proteins and exert a dynamic role in development
by providing the physical basis for cell adhesion and controlling cell growth. In the present
study, we examined changes in the expression of ß1 integrins and its associated ... Cited by 26 - Related articles - All 5 versions
