IM Heid, SA Wagner, H Gohlke, B Iglseder, JC Mueller, … - Diabetes, 2006 - Am Diabetes Assoc The associations of the adiponectin (APM1) gene with parameters of the metabolic syndrome
are inconsistent. We performed a systematic investigation based on fine-mapped single nucleotide
polymorphisms (SNPs) highlighting the genetic architecture and their role in modulating ... Cited by 53 - Related articles - BL Direct - All 6 versions
BS Sutton, S Weinert, CD Langefeld, AH Williams, JK … - Human genetics, 2005 - Springer Abstract Adiponectin, coded for by the APM1 gene, is a novel adipocyte-derived hormone implicated
in energy homeostasis and obesity. Several genetic studies have observed evidence of association
between APM1 gene polymorphisms and features of the metabolic syndrome, such as ... Cited by 28 - Related articles - All 3 versions
- ►pubget.com [PDF] F Vasseur, N Helbecque, S Lobbens, V Vasseur- … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Morbid obesity (BMI>40 kg/ m 2 ) affecting 0.5–5% of the adult population
worldwide is a major risk factor for type 2 diabetes. We aimed to elu- cidate the genetic bases
of diabetes associated with obesity (diabesity), and to analyse the impact of corpulence ... Cited by 53 - Related articles - All 4 versions
- ►geno-type.com [PDF] N Bouatia-Naji, D Meyre, S Lobbens, K Séron, F … - Diabetes, 2006 - Am Diabetes Assoc Common single nucleotide polymorphisms (SNPs) in the ACDC adiponectin encoding gene
have been associated with insulin resistance and type 2 diabetes in several populations.
Here, we investigate the role of SNPs –11,377C>G, –11,391G>A, +45T>G, and +276G>T ... Cited by 48 - Related articles - BL Direct - All 7 versions
F Gibson, P Froguel - Diabetes, 2004 - Am Diabetes Assoc We have carried out a detailed reexamination of the genetics of the APM1 locus and its contribution
to the genetic basis of type 2 diabetes susceptibility in the French Caucasian population. The
G allele of single nucleotide polymorphism −11426 in the APM1 promoter showed ... Cited by 37 - Related articles - BL Direct - All 4 versions
JG Woo, LM Dolan, R Deka, RD Kaushal, Y Shen, P … - Diabetes, 2006 - Am Diabetes Assoc Adiponectin, an adipocyte protein important in insulin sensitization and cardioprotection, has
a strong genetic component. We hypothesized that variants in the adiponectin gene (adipocyte
collagen–domain containing [ACDC]) contribute to adiponectin levels in a biracial ... Cited by 23 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org X Guo, MF Saad, CD Langefeld, AH Williams, J Cui, KD … - Diabetes, 2006 - Am Diabetes Assoc Adiponectin (APM1) is an adipocyte-derived peptide that contributes to glucose, lipid, and energy
homeostasis. We assessed the genetic basis of plasma adiponectin in Hispanic-American and
African-American families enrolled through the Insulin Resistance Atherosclerosis Study ... Cited by 14 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org TI Pollin, K Tanner, JR O'Connell, SH Ott, CM Damcott, … - Diabetes, 2005 - Am Diabetes Assoc We performed a genome-wide linkage scan of plasma adiponectin levels in 569 nondiabetic
participants in the Amish Family Diabetes Study. The highest logarithm of odds (LOD) score
(2.13; P = 0.0009) occurred on chromosome 3q27 between markers D3S1602 and ... Cited by 49 - Related articles - All 10 versions
Y Jang, JH Lee, OY Kim, SJ Koh, JS Chae, JH Woo, H … - Metabolism, 2006 - Elsevier This study aimed to determine whether polymorphisms of the adiponectin (ACDC) gene independently
contribute to insulin resistance (IR) and other cardiovascular disease (CVD) risk factors in
nonobese, nondiabetic Korean men after adjusting for major environmental factors that ... Cited by 28 - Related articles - All 18 versions
V de Courten… - Diabetes, 2005 - Am Diabetes Assoc Adiponectin is an abundant adipose tissue-derived protein with important metabolic effects. Plasma
adiponectin levels are decreased in obese individuals, and low adiponectin levels predict insulin
resistance and type 2 diabetes. Two variants in the adiponectin gene ACDC have been ... Cited by 39 - Related articles - All 6 versions
