- ►diabetesjournals.org L Kang, AA Dunn-Meynell, VH Routh, LD Gaspers, Y … - Diabetes, 2006 - Am Diabetes Assoc To test the hypothesis that glucokinase is a critical regulator of neuronal glucosensing,
glucokinase activity was increased, using a glucokinase activator drug, or decreased, using RNA
interference combined with calcium ... Cited by 49 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org R Wang, X Liu, ST Hentges, AA Dunn-Meynell, BE … - Diabetes, 2004 - Am Diabetes Assoc Glucosensing neurons in the hypothalamic arcuate nucleus (ARC) were studied using
electrophysiological and immunocytochemical techniques in neonatal male Sprague-Dawley rats. We
identified glucose-excited and - ... Cited by 106 - Related articles - BL Direct - All 5 versions
L Kang, VH Routh, EV Kuzhikandathil, LD Gaspers, BE … - Diabetes, 2004 - Am Diabetes Assoc To evaluate potential mechanisms for neuronal glucosensing, fura-2 Ca 2+ imaging and single-cell
RT-PCR were carried out in dissociated ventromedial hypothalamic nucleus (VMN) neurons.
Glucose-excited (GE) neurons ... Cited by 94 - Related articles - BL Direct - All 7 versions
AA Dunn-Meynell, VH Routh, L Kang, L Gaspers, BE … - Diabetes, 2002 - Am Diabetes Assoc Specialized neurons utilize glucose as a signaling molecule to alter their firing rate.
Glucose-excited (GE) neurons increase and glucose-inhibited (GI) neurons reduce activity as ambient
glucose levels rise. ... Cited by 116 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org MG de Vries, LM Arseneau, ME Lawson, JL Beverly - Diabetes, 2003 - Am Diabetes Assoc The activity of neurons in the ventromedial hypothalamus (VMH) important for initiating compensatory
responses to hypoglycemia is influenced by ambient glucose concentration. In the present study, we
used in vivo microdialysis to ... Cited by 65 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org Z Song, VH Routh - Diabetes, 2005 - Am Diabetes Assoc Glucose directly alters the action potential frequency of glucosensing neurons in the ventromedial
hypothalamic nucleus (VMN). Glucose-excited neurons increase, and glucose-inhibited neurons
decrease, their action potential ... Cited by 61 - Related articles - All 7 versions
- ►physiology.org R Wang, C Cruciani-Guglielmacci, S … - Journal of …, 2006 - Am Physiological Soc Pharmacological manipulation of fatty acid metabolism in the hypothalamic arcuate nucleus (ARC)
alters energy balance and glucose homeostasis. Thus, we tested the hypotheses that distinctive
populations of ARC neurons are ... Cited by 35 - Related articles - BL Direct - All 4 versions
BE Levin, VH Routh, L Kang, NM Sanders, AA Dunn- … - Diabetes, 2004 - ncbi.nlm.nih.gov Glucosensing neurons are specialized cells that use glucose as a signaling molecule to alter their
action potential frequency in response to variations in ambient glucose levels. Glucokinase (GK)
appears to be the primary regulator ... Cited by 141 - Related articles - BL Direct - All 2 versions
- ►diabetesjournals.org X Fioramonti, A Lorsignol, A Taupignon, L Pénicaud - Diabetes, 2004 - Am Diabetes Assoc Glucose is known to modify electrical activity of neurons in different hypothalamic areas such as
the arcuate nucleus (ARC) or the ventromedian nucleus. In these structures, it has been demonstrated
that glucose-induced excitation of ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org NM Sanders, AA Dunn-Meynell, BE Levin - Diabetes, 2004 - Am Diabetes Assoc Glucokinase (GK) is hypothesized to be the critical glucosensor of pancreatic β-cells and
hypothalamic glucosensing neurons. To understand the role of GK in glucoprivic counterregulatory
responses, we injected alloxan, a ... Cited by 36 - Related articles - BL Direct - All 4 versions
