- ►diabetesjournals.org JY Jeon, RL Bradley, EG Kokkotou, FE Marino, X Wang … - Diabetes, 2006 - Am Diabetes Assoc Ablation of the hypothalamic peptide, melanin-concentrating hormone (MCH), leads to a lean
phenotype and resistance to diet-induced obesity. Observation of MCH −/− mice at older ages
suggested that these effects persist in mice >1 year old. Leanness secondary to caloric ... Cited by 14 - Related articles - BL Direct - All 4 versions
JY Jeon, RL Bradley, EG Kokkotou, FE Marino, X … - 糖尿病学杂志, 2006 - journal.shouxi.net Ablation of the hypothalamic peptide, melanin-concentrating hormone (MCH), leads to a lean
phenotype and resistance to diet-induced obesity. Observation of MCHeC/eC mice at older ages
suggested that these effects persist in mice >1 year old. Leanness secondary to caloric ... Related articles - Cached
- ►physiology.org E Kokkotou, JY Jeon, X Wang, FE Marino, … - American Journal of …, 2005 - Am Physiological Soc Genetics and environment contribute to the development of obesity, in both humans and
rodents. However, the potential interaction between genes important in energy balance, strain
background, and dietary environment has been only minimally explored. We investigated ... Cited by 42 - Related articles - BL Direct - All 4 versions
- ►endojournals.org S Mashiko, A Ishihara, A Gomori, R Moriya, M Ito, H … - Endocrinology, 2005 - Endocrine Soc Melanin-concentrating hormone (MCH) is a cyclic orexigenic peptide expressed in the lateral
hypothalamus, which plays an important role in regulating energy balance. To elucidate the physiological
role of MCH in obesity development, the present study examined the effect of a selective ... Cited by 22 - Related articles - All 6 versions
D Zhou, Z Shen, AM Strack, DJ Marsh, LP Shearman - Regulatory peptides, 2005 - Elsevier Mch1r-deficient (Mch1r −/− ) mice are hyperphagic, hyperactive, lean, and resistant to diet-induced
obesity. To examine whether the MCH1R is involved in regulating activity-based energy
expenditure, we investigated voluntary wheel running (WR) activity of wild-type (WT) and ... Cited by 25 - Related articles - All 3 versions
- ►jneurosci.org T Alon, JM Friedman - Journal of Neuroscience, 2006 - Soc Neuroscience The observation that loss of orexin (hypocretin) neurons causes human narcolepsy raises the
possibility that other acquired disorders might also result from loss of hypothalamic neurons.
To test this possibility for body weight, mice with selective loss of melanin concentrating ... Cited by 20 - Related articles - BL Direct - All 5 versions
P Pissios, U Ozcan, E Kokkotou, T Okada, CW Liew, S … - Diabetes, 2007 - Am Diabetes Assoc Melanin concentrating hormone (MCH) is a hypothalamic neuropeptide known to play a critical
role in energy balance. We have previously reported that overexpression of MCH is associated
with mild obesity. In addition, mice have substantial hyperinsulinemia and islet ... Cited by 14 - Related articles - BL Direct - All 6 versions
DG Smith, H Qi, P Svenningsson, M Wade, … - SYNAPSE-NEW …, 2008 - interscience.wiley.com The melanin-concentrating hormone (MCH) system is anatomically and functionally interlaced
with the mesocorticolimbic dopamine system. Therefore, we investigated whether MCH 1 receptor
knockout (KO) mice are more susceptible than wild-type (WT) mice to psychostimulant- ... Cited by 7 - Related articles - BL Direct - All 3 versions
DB Westerfield, PK Pang, JM Burns - General and comparative …, 1980 - ncbi.nlm.nih.gov 1: Gen Comp Endocrinol. 1980 Dec;42(4):494-9. Some characteristics of
melanophore-concentrating hormone (MCH) from teleost pituitary glands. Westerfield
DB, Pang PK, Burns JM. Mesh Terms: Animals; Biological Assay; ... Cited by 8 - Related articles
P Pissios, RL Bradley, E Maratos-Flier - Endocrine reviews, 2006 - Endocrine Soc Melanin-concentrating hormone (MCH) is a cyclic peptide originally identified as a
17-amino-acid circulating hormone in teleost fish, where it is secreted by the pituitary in response
to stress and environmental stimuli. In fish, MCH lightens skin color by stimulating ... Cited by 43 - Related articles - BL Direct - All 4 versions
