- ►shouxi.net CG Ostenson, H Gaisano, L Sheu, A Tibell, T … - Diabetes, 2006 - Am Diabetes Assoc Exocytosis of insulin is dependent on the soluble N-ethylmaleimide attachment
protein receptor (SNARE) complex proteins in the B-cells. We assessed insulin
release as well as gene and protein expression of SNARE complex protein in ... Cited by 49 - Related articles - BL Direct - All 5 versions
- ►endojournals.org HY Gaisano, CG Ostenson, L Sheu, MB … - Endocrinology, 2002 - Endocrine Soc The role of glucotoxicity in dysregulation of islet exocytotic soluble
N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex
proteins and insulin response was explored in the hyperglycemic ... Cited by 40 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] CB Chan, RM MacPhail, L Sheu, MB Wheeler … - Diabetes, 1999 - Am Diabetes Assoc In normal isolated ß-cells, the response to glucose is heterogeneous and
characterized by an increasing num- ber of secretory cells as glucose
concentration rises (Pipeleers DG, Kiekens R, Ling Z, Wilikens A, Schuit F: ... Cited by 46 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] S Nagamatsu, Y Nakamichi, C Yamamura, S … - Diabetes, 1999 - Am Diabetes Assoc Page 1. DIABETES, VOL. 48, DECEMBER 1999 2367 Decreased Expression of t-SNARE,
Syntaxin 1, and SNAP-25 in Pancreatic ß-Cells Is Involved in ... Cited by 100 - Related articles - BL Direct - All 5 versions
W Zhang, A Khan, CG Östenson, PO Berggren, … - Biochemical and Biophysical Research …, 2002 - Elsevier Exocytosis is regulated by exocytotic proteins, which are present in
insulin-secreting β-cells and play regulatory roles in insulin secretion.
Non-insulin dependent diabetes mellitus (type 2 diabetes) is a disease ... Cited by 29 - Related articles - BL Direct - All 4 versions
A Abderrahmani, S Cheviet, M Ferdaoussi, T … - The EMBO Journal, 2006 - pubmedcentral.nih.gov The GTPases Rab3a and Rab27a and their effectors Granuphilin/Slp4 and Noc2 are
essential regulators of neuroendocrine secretion. Chronic exposure of pancreatic
β-cells to supraphysiological glucose levels decreased selectively the ... Cited by 28 - Related articles - BL Direct - All 9 versions
MB Wheeler, L Sheu, M Ghai, A Bouquillon, G … - Endocrinology, 1996 - Endocrine Soc Page 1. 0013.7227/96/$03 00/o Endocrinology Copyright 0 1996 by The Endocrine
Society Vol. 137. No. 4 Prrnfrd in USA Characterization ... Cited by 150 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org T Tsuboi, MA Ravier, LE Parton, GA Rutter - Diabetes, 2006 - Am Diabetes Assoc The mechanism(s) by which chronic hyperglycemia impairs glucose-stimulated
insulin secretion is poorly defined. Here, we compare the "nanomechanics" of
single exocytotic events in primary rat pancreatic ß-cells cultured for 48 ... Cited by 25 - Related articles - BL Direct - All 6 versions
- ►shouxi.net PPL Lam, YM Leung, L Sheu, J Ellis, RG … - Diabetes, 2005 - Am Diabetes Assoc Soluble N-ethylmaleimide–sensitive factor (NSF) attachment protein receptor
(SNARE) protein syntaxin-1A (STX-1A) plays a role not only in exocytosis, but
also binds and regulates Ca 2+ and K + (voltage-gated K + and ATP-sensitive ... Cited by 17 - Related articles - BL Direct - All 7 versions
- ►jbc.org L Sheu, EA Pasyk, J Ji, X Huang, X Gao, F … - Journal of Biological Chemistry, 2003 - ASBMB The slower kinetics of insulin release from pancreatic islet beta cells, as
compared with other regulated secretory processes such as chromaffin granule
secretion, can in part be explained by the small number of the insulin ... Cited by 51 - Related articles - BL Direct - All 4 versions
