- ►shouxi.net OJ How, E Aasum, DL Severson, WY Chan, … - Diabetes, 2006 - Am Diabetes Assoc Altered cardiac metabolism and function (diabetic cardiomyopathy) has been
observed in diabetes. We hypothesize that cardiac efficiency, the ratio of
cardiac work (pressure-volume area [PVA]) and myocardial oxygen consumption ... Cited by 58 - Related articles - BL Direct - All 5 versions
- ►endojournals.org J Buchanan, PK Mazumder, P Hu, G … - Endocrinology, 2005 - Endocrine Soc Hyperglycemia is associated with altered myocardial substrate use, a condition
that has been hypothesized to contribute to impaired cardiac performance. The
goals of this study were to determine whether changes in cardiac ... Cited by 69 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org S Boudina, S Sena, BT O'Neill, P Tathireddy, … - Circulation, 2005 - Am Heart Assoc Methods and Results— Cardiac function, M O 2 , mitochondrial respiration, and
ATP synthesis were measured in 9-week-old ob/ob and control mouse hearts.
Contractile function and M O 2 in glucose-perfused ob/ob hearts were ... Cited by 75 - Related articles - All 10 versions
- ►physiology.org S Boudina, ED Abel - Physiology, 2006 - Am Physiological Soc Diabetes is a worldwide epidemic (112). Cardiovascular disease remains the major
cause of morbidity and mortality in people with diabetes. Epidemiological
studies suggest that the prevalence of heart failure exceeds that which can ... Cited by 39 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org E Aasum, AD Hafstad, DL Severson, TS … - Diabetes, 2003 - Am Diabetes Assoc Glucose and palmitate metabolism and contractile function were measured with ex
vivo perfused working hearts from control (db/+) and diabetic (db/db) female
mice at 6, 10–12, and 16–18 weeks of age. Palmitate oxidation was ... Cited by 102 - Related articles - BL Direct - All 4 versions
PK Mazumder, BT O'Neill, MW Roberts, J … - Diabetes, 2004 - Am Diabetes Assoc Diabetes alters cardiac substrate metabolism. The cardiac phenotype in
insulin-resistant states has not been comprehensively characterized. The goal of
these studies was to determine whether the hearts of leptin-deficient ... Cited by 99 - Related articles - BL Direct - All 6 versions
- ►physiology.org OJ How, E Aasum, S Kunnathu, DL Severson, … - American Journal of Physiology- Heart and Circulatory …, 2005 - Am Physiological Soc In the present study, we tested the reliability of measurements of
pressure-volume area (PVA) and oxygen consumption (M O 2 ) in ex vivo mouse
hearts, combining the use of a miniaturized conductance catheter and a ... Cited by 38 - Related articles - All 4 versions
AJ Murray, M Panagia, D Hauton, GF Gibbons, … - Diabetes, 2005 - Am Diabetes Assoc Diabetic patients have abnormal cardiac energy metabolism associated with high
plasma free fatty acid (FFA) concentrations. We investigated whether high plasma
FFAs increase mitochondrial uncoupling protein (UCP) levels in the mouse ... Cited by 53 - Related articles - BL Direct - All 5 versions
A Ellen, C Marie - Canadian journal of physiology and pharmacology, 2005 - ingentaconnect.com Abstract: Peroxisome proliferator-activated receptor-α (PPARα) regulates the
expression of fatty acid (FA) oxidation genes in liver and heart. Although
PPARα ligands increased FA oxidation in cultured cardiomyocytes, the ... Cited by 24 - Related articles - All 7 versions
- ►physiology.org P Yue, T Arai, M Terashima, AY Sheikh, F … - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc The db/db mouse is a well-established model of diabetes. Previous reports have
documented contractile dysfunction (ie, cardiomyopathy) in these animals,
although the extant literature provides limited insights into cardiac ... Cited by 20 - Related articles - BL Direct - All 4 versions
