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Scholar Results 1 - 10 of about 101 related to Bouatia-Naji: ACDC/adiponectin polymorphisms are associated with severe childhood and adult obesity. (0.15 sec) 

ACDC/adiponectin polymorphisms are associated with severe childhood and adult …

- geno-type.com [PDF] 
N Bouatia-Naji, D Meyre, S Lobbens, K Séron, F … - Diabetes, 2006 - Am Diabetes Assoc
Common single nucleotide polymorphisms (SNPs) in the ACDC adiponectin encoding gene
have been associated with insulin resistance and type 2 diabetes in several populations.
Here, we investigate the role of SNPs –11,377C>G, –11,391G>A, +45T>G, and +276G>T ...
Cited by 48 - Related articles - BL Direct - All 7 versions

Hypoadiponectinaemia and high risk of type 2 diabetes are associated with …

- pubget.com [PDF] 
F Vasseur, N Helbecque, S Lobbens, V Vasseur- … - Diabetologia, 2005 - Springer
Abstract Aims/hypothesis: Morbid obesity (BMI>40 kg/ m 2 ) affecting 0.5–5% of the adult population
worldwide is a major risk factor for type 2 diabetes. We aimed to elu- cidate the genetic bases
of diabetes associated with obesity (diabesity), and to analyse the impact of corpulence ...
Cited by 53 - Related articles - All 4 versions

The Promoter Region of the Adiponectin Gene Is a Determinant in Modulating …


A Petrone, S Zavarella, A Caiazzo, G Leto, M Spoletini, … - Obesity, 2006 - nature.com
* Endocrinology, Department of Clinical Sciences, La Sapienza University, Rome, Italy. ... † Center
for Nutrition and Dietetics of the Department of Pediatrics, La Sapienza University, Rome,
Italy. ... ‡ Department of Public Health Sciences, La Sapienza University, Rome, Italy.
Cited by 11 - Related articles - All 3 versions

Genetic architecture of the APM1 gene and its influence on adiponectin plasma …


IM Heid, SA Wagner, H Gohlke, B Iglseder, JC Mueller, … - Diabetes, 2006 - Am Diabetes Assoc
The associations of the adiponectin (APM1) gene with parameters of the metabolic syndrome
are inconsistent. We performed a systematic investigation based on fine-mapped single nucleotide
polymorphisms (SNPs) highlighting the genetic architecture and their role in modulating ...
Cited by 53 - Related articles - BL Direct - All 6 versions

Multigenic control of serum adiponectin levels: evidence for a role of the APM1 …

- physiology.org
C Menzaghi, T Ercolino, L Salvemini, A … - Physiological …, 2004 - Am Physiological Soc
Adiponectin is a circulating enhancer of insulin action that is secreted by the adipose tissue.
In epidemiological studies, serum levels of this protein predict the risk of type 2 diabetes and
cardiovascular events. Serum adiponectin levels have been associated with variants at ...
Cited by 35 - Related articles - All 4 versions

[PDF] ACDC/Adiponectin and PPAR-g Gene Polymorphisms: Implications for Features of …


LB Tankó, A Siddiq, C Lecoeur, PJ Larsen, C … - Obesity research, 2005 - geno-type.com
László B. Tankó,* Afshan Siddiq,† Cécile Lecoeur,† Philip J. Larsen,‡ Claus Christiansen,* Andrew
Walley,† and Philippe Froguel†§ ... Abstract TANKO´, LA´SZLO´ B., AFSHAN SIDDIQ, CE´CILE
LECOEUR, PHILIP J. LARSEN, CLAUS ... CHRISTIANSEN, ANDREW WALLEY, AND ...
Cited by 25 - Related articles - View as HTML - BL Direct - All 4 versions

Hypoadiponectinemia is associated with progression toward type 2 diabetes and …

- diabetesjournals.org
PEH Schwarz, GW Towers, S Fischer, S … - Diabetes Care, 2006 - Am Diabetes Assoc
RESULTS—Tertiles of the adjusted adiponectin levels were associated with single nucleotide
polymorphism −11391G>A and −11377C>G haplotypes (P < 0.0001). Carriers of the
intermediate/high-level haplotype combination showed a bisected diabetes risk at the ...
Cited by 27 - Related articles - BL Direct - All 5 versions

Genetics of the APM1 locus and its contribution to type 2 diabetes susceptibility in …


F Gibson, P Froguel - Diabetes, 2004 - Am Diabetes Assoc
We have carried out a detailed reexamination of the genetics of the APM1 locus and its contribution
to the genetic basis of type 2 diabetes susceptibility in the French Caucasian population. The
G allele of single nucleotide polymorphism −11426 in the APM1 promoter showed ...
Cited by 37 - Related articles - BL Direct - All 4 versions

Common polymorphisms in the adiponectin gene ACDC are not associated with …


V de Courten… - Diabetes, 2005 - Am Diabetes Assoc
Adiponectin is an abundant adipose tissue-derived protein with important metabolic effects. Plasma
adiponectin levels are decreased in obese individuals, and low adiponectin levels predict insulin
resistance and type 2 diabetes. Two variants in the adiponectin gene ACDC have been ...
Cited by 39 - Related articles - All 6 versions

Adiponectin polymorphisms, adiposity and insulin metabolism: HERITAGE family …


O Ukkola, M Santaniemi, T Rankinen, AS Leon … - Annals of …, 2005 - informahealthcare.com
Abstract Aims/hypothesis. Adiponectin is an adipocytokine with lowered blood levels in obesity
and Type 2 diabetes mellitus. We sought to define the specific effects of different alleles of the
gene encoding adiponectin. Methods. We studied the associations of adiponectin gene ...
Cited by 17 - Related articles - All 8 versions


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