L Huo, HJ Grill, C Bjørbæk - Diabetes, 2006 - Am Diabetes Assoc Proopiomelanocortin (POMC) neurons in the arcuate nucleus (ARC) of the
hypothalamus are activated by leptin and mediate part of leptin's central
actions to influence energy balance. However, little is known about ... Cited by 33 - Related articles - BL Direct - All 5 versions
- ►endojournals.org KLJ Ellacott, IG Halatchev, RD Cone - Endocrinology, 2006 - Endocrine Soc The central melanocortin system plays a key role in the regulation of energy
homeostasis. Neurons containing the peptide precursor proopiomelanocortin (POMC)
are found at two sites in the brain, the arcuate nucleus of the ... Cited by 30 - Related articles - BL Direct - All 4 versions
- ►endojournals.org L Huo, L Maeng, C Bjorbaek, HJ Grill - Endocrinology, 2007 - Endocrine Soc Leptin reduces food intake by an unspecified mechanism. Studies show that
forebrain ventricular leptin delivery increases the inhibitory effects of
gastrointestinal (GI) stimulation on intake and amplifies the ... Cited by 28 - Related articles - BL Direct - All 4 versions
OI Challenges - Nature neuroscience, 2004 - nature.com Supplementary Fig. 1 (jpg 39K) Feeding activates NTS POMC neurons. (a) c-Fos-IR
neurons in the NTS 60 minutes after food intake (b) POMC-EGFP-IR cells in the
NTS 60 minutes after food intake. (c) Colocalization of c-Fos and POMC in ... Cited by 97 - Related articles - BL Direct - All 5 versions
- ►endojournals.org H Munzberg, L Huo, EA Nillni, AN Hollenberg … - Endocrinology, 2003 - Endocrine Soc Leptin acts on the brain to regulate body weight and neuroendocrine function.
Proopiomelanocortin (POMC) neurons in the hypothalamus are important targets of
leptin. These cells express the leptin receptor ObRb, and leptin can ... Cited by 104 - Related articles - BL Direct - All 3 versions
- ►endojournals.org DL Williams, JM Kaplan, HJ Grill - Endocrinology, 2000 - Endocrine Soc Fourth intracerebroventricular (4th-icv) administration of the melanocortin-3/4
receptor (MC3/4-R) agonist, MTII, reduces food intake; the antagonist, SHU9119,
increases feeding. The dorsal motor nucleus of the vagus nerve (DMX) ... Cited by 73 - Related articles - BL Direct - All 3 versions
- ►nih.gov L Guo, H Munzberg, RC Stuart, EA Nillni, C … - Science's STKE, 2004 - stke.sciencemag.org Abstract: The central melanocortin system is critical in the regulation of
appetite and body weight, and leptin exerts its anorexigenic actions partly by
increasing hypothalamic proopiomelanocortin (POMC) expression. The ... Cited by 28 - Related articles - BL Direct - All 9 versions
- ►cell.com PJ Enriori, AE Evans, P Sinnayah, EE Jobst, … - Cell Metabolism, 2007 - Elsevier Despite high leptin levels, most obese humans and rodents lack responsiveness to
its appetite-suppressing effects. We demonstrate that leptin modulates NPY/AgRP
and α-MSH secretion from the ARH of lean mice. High-fat diet-induced obese ... Cited by 69 - Related articles - All 11 versions
- ►endojournals.org HJ Grill, MW Schwartz, JM Kaplan, JS Foxhall, … - Endocrinology, 2002 - Endocrine Soc Three experiments were performed to investigate the hypothesis that leptin
action within the caudal brain stem (CBS) contributes to its intake inhibitory
effects. The first experiment evaluated the anatomical distribution of ... Cited by 166 - Related articles - BL Direct - All 5 versions
MR Hayes, KP Skibicka, KK Bence, HJ Grill - Endocrinology, 2009 - Endocrine Soc The fuel-sensing enzyme AMP-activated protein kinase (AMPK) has been implicated
in central nervous system control of energy balance. Hypothalamic AMPK activity
is increased by food deprivation, and this elevation is inhibited by ... Cited by 8 - Related articles - All 3 versions
