- ►diabetesjournals.org W Zhang, L Lilja, SA Mandic, J Gromada, K … - Diabetes, 2006 - Am Diabetes Assoc Tomosyn, a syntaxin-binding protein, is capable of dissociating mammalian
homolog of the Caenorhabditis elegans unc-18 gene from syntaxin and is involved
in the regulation of exocytosis. We have investigated the expression, ... Cited by 15 - Related articles - BL Direct - All 5 versions
- ►rupress.org T Baba, T Sakisaka, S Mochida, Y Takai - Journal of Cell Biology, 2005 - jcb.rupress.org Neurotransmitter is released from nerve terminals by Ca 2+ -dependent exocytosis
through many steps. SNARE proteins are key components at the priming and fusion
steps, and the priming step is modulated by cAMP-dependent protein kinase ... Cited by 27 - Related articles - BL Direct - All 11 versions
- ►biologists.org S Cheviet, P Bezzi, R Ivarsson, E Renstrom, D … - Journal of Cell Science, 2006 - jcs.biologists.org Although the assembly of a ternary complex between the SNARE proteins
syntaxin-1, SNAP25 and VAMP2 is known to be crucial for insulin exocytosis, the
mechanisms controlling this key event are poorly understood. We found that ... Cited by 13 - Related articles - BL Direct - All 5 versions
EP Kwan, HY Gaisano - Diabetes Obes Metab, 2007 - interscience.wiley.com Exocytosis of insulin vesicles in the pancreatic β-cell involves a sequence of
regulated events, whose normal function and efficient adaptation to increased
demand are essential for the maintenance of glucose homeostasis. These ... Cited by 4 - Related articles - All 2 versions
M Dybbs, J Ngai, JM Kaplan - PLoS Genet, 2005 - genetics.plosjournals.org Forward genetic screens have been used as a powerful strategy to dissect complex
biological pathways in many model systems. A significant limitation of this
approach has been the time-consuming and costly process of positional ... Cited by 19 - Related articles - Cached - All 10 versions
- ►jbc.org SE Gladycheva, AD Lam, J Liu, M D'Andrea- … - Journal of Biological Chemistry, 2007 - ASBMB Tomosyn, a soluble R-SNARE protein identified as a binding partner of the
Q-SNARE syntaxin 1A, is thought to be critical in setting the level of
fusion-competent SNARE complexes for neurosecretion. To date, there has ... Cited by 6 - Related articles - All 6 versions
- ►physoc.org EO Gracheva, AO Burdina, D Touroutine, M … - The Journal of Physiology, 2007 - Physiological Soc The SNARE proteins, syntaxin, SNAP-25 and synaptobrevin form a tertiary complex
essential for vesicle fusion. Proteins that influence SNARE complex assembly are
therefore likely to be important regulators of fusion events. In this study ... Cited by 5 - Related articles - BL Direct - All 6 versions
AJA Groffen, L Jacobsen, D Schut, M Verhage - Journal of neurochemistry, 2005 - interscience.wiley.com Tomosyn was previously identified as a syntaxin-binding protein that inhibits
soluble NSF (n-ethylmaleimide-sensitive fusion protein) attachment protein
receptor (SNARE)-mediated secretion. We set out to investigate the ... Cited by 14 - Related articles - All 4 versions
EO Gracheva, AO Burdina, AM Holgado, M … - PLoS Biol, 2006 - biology.plosjournals.org Caenorhabditis elegans TOM-1 is orthologous to vertebrate tomosyn, a cytosolic
syntaxin-binding protein implicated in the modulation of both constitutive and
regulated exocytosis. To investigate how TOM-1 regulates exocytosis of ... Cited by 28 - Related articles - Cached - All 10 versions
- ►nih.gov O Yizhar, U Matti, R Melamed, Y Hagalili, D … - Proceedings of the National Academy of Sciences of …, 2004 - National Acad Sciences Neurotransmitter release is a multistep process that is coordinated by a large
number of synaptic proteins and depends on proper protein–protein
interactions. Using morphological, capacitance, and amperometric ... Cited by 46 - Related articles - BL Direct - All 8 versions
