- ►diabetesjournals.org N Warwar, S Efendic, CG Östenson, EP Haber, E … - Diabetes, 2006 - Am Diabetes Assoc Glucose metabolism affects most major signal pathways in pancreatic β-cells. Multiple protein
kinases, including protein kinase C (PKC) isoenzymes, are involved in these effects; however, their
role is poorly defined. Moreover, ... Cited by 19 - Related articles - BL Direct - All 5 versions
L Carpenter, CJ Mitchell, ZZ Xu, P Poronnik, GW Both, … - Diabetes, 2004 - Am Diabetes Assoc The role of protein kinase C (PKC) in glucose-stimulated insulin secretion (GSIS) is controversial.
Using recombinant adenoviruses for overexpression of PKCα and PKCδ, in both wild-type (WT) and
kinase-dead (KD) forms, we here ... Cited by 13 - Related articles - BL Direct - All 5 versions
N Warwar, S Efendic, CG Ostenson, EP Haber, E … - DIABETES, 2006 - Am Diabetes Assoc Glucose metabolism affects most major signal pathways in pancreatic -cells. Multiple protein
kinases, including pro- tein kinase C (PKC) isoenzymes, are involved in these effects; however,
their role is poorly defined. ... Related articles
N Warwar, S Efendic - 糖尿病学杂志, 2006 - journal.shouxi.net Glucose metabolism affects most major signal pathways in pancreatic -cells. Multiple protein
kinases, including protein kinase C (PKC) isoenzymes, are involved in these effects; however, their
role is poorly defined. Moreover, ... Related articles - Cached
H Zhang, M Nagasawa, S Yamada, H … - The Journal of …, 2004 - Physiological Soc The present study was conducted to evaluate the role of conventional protein kinase C (PKC) in
calcium-evoked insulin secretion. In rat β cells transfected with green fluorescent protein-tagged
PKC-α (PKC-α–EGFP), a ... Cited by 13 - Related articles - All 7 versions
WS Zawalich, KC Zawalich - Molecular and Cellular Endocrinology, 2001 - Elsevier The contribution of protein kinase C (PKC) to the regulation of insulin release from perifused
islets was explored using staurosporine or Gö 6976 to inhibit the enzyme. Phorbol 12-myristate
13-acetate (PMA, 500 nM) addition ... Cited by 23 - Related articles - All 4 versions
AM Hennige, A Fritsche, V Strack, C Weigert, H … - … and Biophysical Research …, 2002 - Elsevier Protein kinase C seems to be linked to the regulation of insulin secretion as well as mitogenic
signaling in pancreatic β cells. To study the impact of different PKC isoforms on insulin secretion
and mitogenic activity we stably ... Cited by 17 - Related articles - BL Direct - All 8 versions
[CITATION] Oriente F, Paturzo F, Andreozzi F, Zabatta A, Troncone G, Bosch F, Pujol A, …
RC Vasavada, L Wang, Y Fujinaka, KK Takane, TC … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE— Diabetes results from a deficiency of functional β-cells. Previous studies have
identified hepatocyte growth factor (HGF) and parathyroid hormone–related protein (PTHrP) as two
potent β-cell mitogens. The ... Cited by 7 - Related articles - BL Direct - All 3 versions
Y Sawada, B Zhang, F Okajima, T Izumi, T … - Molecular and Cellular …, 2001 - Elsevier Parathyroid hormone-related protein (PTHrP) is reportedly produced in normal islets and insulinomas.
PTHrP induces differentiation in some cell-types and growth in others. We examined whether PTHrP
production is greater in well- ... Cited by 8 - Related articles - All 3 versions
