L Pereira, J Matthes, I Schuster, HH Valdivia, S Herzig, … - Diabetes, 2006 - Am Diabetes Assoc Cardiovascular disease is the leading cause of death in the diabetic population. However, molecular
mechanisms underlying diabetic cardiomyopathy remain unclear. We analyzed Ca 2+ -induced
Ca 2+ release and excitation-contraction coupling in db/db obese type 2 diabetic mice ... Cited by 43 - Related articles - BL Direct - All 6 versions
L Pereira, J Matthes, I Schuster, HH Valdivia, S Herzig, … - DIABETES, 2006 - Am Diabetes Assoc Cardiovascular disease is the leading cause of death in the diabetic population. However, molecular
mechanisms under- lying diabetic cardiomyopathy remain unclear. We analyzed Ca 2 -induced
Ca 2 release and excitation-contraction cou- pling in db/db obese type 2 diabetic mice ... Related articles
- ►diabetesjournals.org DD Belke, EA Swanson, WH Dillmann - Diabetes, 2004 - Am Diabetes Assoc Although it is known that insulin-dependent (type 1) diabetes results in depressed contractile
performance associated with diminished sarcoendoplasmic reticular Ca 2+ -ATPase
(SERCA2a) activity, findings in insulin-resistant (type 2) diabetes suggest a less clear ... Cited by 53 - Related articles - BL Direct - All 6 versions
- ►physiology.org N Yaras, A Bilginoglu, G Vassort, B … - American Journal of …, 2007 - Am Physiological Soc Stimulation of local renin-angiotensin system and increased levels of oxidants characterize the
diabetic heart. Downregulation of ANG II type 1 receptors (AT 1 ) and enhancement in PKC activity
in the heart point out the role of AT 1 blockers in diabetes. The purpose of this study was ... Cited by 14 - Related articles - BL Direct - All 5 versions
X Liu, H Suzuki, R Sethi, PS Tappia, N … - ANNALS-NEW …, 2006 - interscience.wiley.com Abstract: Although the defects in the sarcolemma (SL) and sarcoplasmic reticulum (SR) membranes
are known to be associated with cardiac dysfunction in chronic diabetes, very little information
regarding the mechanisms of these membrane abnormalities is available in the literature. ... Cited by 8 - Related articles - BL Direct - All 6 versions
- ►physiology.org VA Lacombe, S Viatchenko-Karpinski, D … - American Journal of …, 2007 - Am Physiological Soc Isolated diastolic dysfunction is found in almost half of asymptomatic patients with well-controlled
diabetes and may precede diastolic heart failure. However, mechanisms that underlie diastolic
dysfunction during diabetes are not well understood. We tested the hypothesis that ... Cited by 10 - Related articles - All 4 versions
XY Zhao, SJ Hu, J Li, Y Mou, BP Chen, Q … - Journal of physiology and …, 2006 - ncbi.nlm.nih.gov Diabetic cardiomyopathy is characterized by reduced cardiac contractility due to direct changes
in myocardium function independent of vascular disease. This study is to investigate the alterations
of cardiac sarcoplasmic reticulum Ca2+ -ATPase activity and cardiac function in ... Cited by 12 - Related articles - BL Direct - All 3 versions
- ►physiology.org AD Hafstad, AM Khalid, OJ How, TS … - American Journal of …, 2007 - Am Physiological Soc Hearts from type 2 diabetic (db/db) mice demonstrate altered substrate utilization with high rates
of fatty acid oxidation, decreased functional recovery following ischemia, and reduced cardiac
efficiency. Although db/db mice show overall insulin resistance in vivo, we recently ... Cited by 16 - Related articles - BL Direct - All 5 versions
CH Shao, GJ Rozanski, KP Patel, KR Bidasee - Journal of molecular and …, 2007 - Elsevier Using biochemical/pharmacological approaches, we previously showed that type 2 ryanodine
receptors (RyR2) become dysfunctional in hearts of streptozotocin-induced type 1 diabetic
rats. However, the functional consequence of this observation remains incompletely ... Cited by 9 - Related articles - All 15 versions
- ►physiology.org EE Jweied, RD McKinney, LA Walker, I … - American Journal of …, 2005 - Am Physiological Soc Diabetes mellitus is associated with a distinct cardiomyopathy. Whether cardiac myofilament
function is altered in human diabetes mellitus is unknown. Myocardial biopsies were obtained
from seven diabetic patients and five control, nondiabetic patients undergoing coronary ... Cited by 21 - Related articles - BL Direct - All 4 versions
