- ►diabetesjournals.org R Marfella, MD'Amico, K Esposito, A Baldi, C Di Filippo, … - Diabetes, 2006 - Am Diabetes Assoc The role of ubiquitin-proteasome system in the accelerated atherosclerotic progression of diabetic
patients is unclear. We evaluated ubiquitin-proteasome activity in carotid plaques of asymptomatic
diabetic and nondiabetic patients, as well as the effect of rosiglitazone, a peroxisome ... Cited by 57 - Related articles - BL Direct - All 7 versions
R Marfella, MD'Amico, K Esposito, A Baldi, C Di Filippo, … - pathways, 2006 - Am Diabetes Assoc Page 1. Original Article The Ubiquitin-Proteasome System and Inflammatory Activity in Diabetic
Atherosclerotic Plaques Effects of Rosiglitazone Treatment Raffaele Marfella, 1,2 Michele D'Amico,
2,3 Katherine Esposito, 1,2 Alfonso Baldi, 4 Clara Di Filippo, 2,3 ... Related articles
- ►onlinejacc.org R Marfella, M D'Amico, C Di Filippo, A Baldi, M … - Journal of the American …, 2006 - Elsevier Plaques were obtained from 40 symptomatic and 38 asymptomatic patients undergoing carotid
endarterectomy. Symptomatic patients received 8 mg rosiglitazone (n = 20) or placebo (n =
20) for 4 months before scheduled endarterectomy. Plaques were analyzed for ... Cited by 38 - Related articles - BL Direct - All 25 versions
- ►ahajournals.org J Xu, Y Wu, P Song, M Zhang, S Wang, MH Zou - Circulation, 2007 - Am Heart Assoc Methods and Results— Exposure of human umbilical vein endothelial cells to high glucose concentrations
(30 mmol/L D-glucose) but not to high osmotic conditions (25 mmol/L L-glucose plus 5
mmol/L D-glucose) significantly lowered the levels of both GTPCH protein and BH4. In ... Cited by 21 - Related articles - All 5 versions
- ►onlinejacc.org J Herrmann, WD Edwards, DR Holmes, KL … - Journal of the American …, 2002 - Elsevier The ubiquitin system has been identified as the nonlysosomal pathway of protein
degradation; it is involved in a number of biologic processes crucial to cell and tissue integrity
and therefore, might be potentially involved in the rupture of unstable coronary plaques. Cited by 28 - Related articles - BL Direct - All 10 versions
- ►cardiovascres.org J Herrmann, A Ciechanover, LO Lerman, A … - Cardiovascular …, 2004 - cardiovascres.org During recent years, the ubiquitin–proteasome system has become known as the major pathway
of non-lysosomal degradation of intracellular proteins, involving two sequential steps. In the first
step, multiple moieties of ubiquitin are covalently bound to target proteins to be ... Cited by 80 - Related articles - All 6 versions
- ►ahajournals.org J Kikuchi, Y Furukawa, N Kubo, A Tokura, N … - … , and vascular biology, 2000 - Am Heart Assoc Abstract—Recently, we have found that aggregated low density lipoprotein (agLDL) inhibits apoptosis
of lipid-bearing macrophages, thereby facilitating foam cell formation and atherosclerosis. To
clarify the mechanisms by which agLDL inhibits apoptosis of macrophages, we isolated ... Cited by 31 - Related articles - BL Direct - All 5 versions
- ►onlinejacc.org J Herrmann, SM Soares, LO Lerman, A … - Journal of the American …, 2008 - Am Coll Cardio Found Misfolded or damaged proteins are recognized intracellularly by protein quality
mechanisms. These include chaperones and the ubiquitin-proteasome system, which aim at
restoration of protein function and protein removal, respectively. A number of studies have ... Cited by 9 - Related articles - All 12 versions
- ►nih.gov SZ Duan, CY Ivashchenko, SE Whitesall, … - Journal of Clinical …, 2007 - Am Soc Clin Investig 1 Department of Molecular and Integrative Physiology and 2 Department of Surgery, University
of Michigan Medical School, Ann Arbor, Michigan, USA. 3 Department of Surgery, William Beaumont
Hospital, Royal Oak, Michigan, USA. 4 Department of Internal Medicine, Nephrology ... Cited by 38 - Related articles - BL Direct - All 9 versions
BA Game, A Maldonado, L He, Y Huang - Atherosclerosis, 2005 - Elsevier Antidiabetic drug thiazolidinedione (TZD) also has anti-atherogenic effects. Among these
effects, inhibition of smooth muscle cell (SMC) migration is considered to be essential.
However, the mechanism whereby TZD inhibits SMC migration is not well understood. ... Cited by 13 - Related articles - All 11 versions
