M Bjursell, AK Gerdin, K Ploj, D Svensson, L Svensson, … - Diabetes, 2006 - Am Diabetes Assoc The hypothalamic peptide melanin-concentrating hormone (MCH) plays important roles in energy
homeostasis. Animals overexpressing MCH develop hyperphagia, obesity, and insulin
resistance. In this study, mice lacking both the MCH receptor-1 (MCHr1 knockout) and ... Cited by 14 - Related articles - BL Direct - All 5 versions
MD McBriar, H Guzik, S Shapiro, J Paruchova, … - Journal of medicinal …, 2006 - ncbi.nlm.nih.gov Melanin-concentrating hormone (MCH) is a cyclic, nonadecapeptide expressed in the CNS of
all vertebrates that regulates feeding behavior and energy homeostasis via interaction with the
central melanocortin system. Regulation of this interaction results in modulation of food ... Cited by 18 - Related articles - All 5 versions
R Sakamaki, M UEMOTO, A INUI, A ASAKAWA, N … - International journal of …, 2005 - cat.inist.fr Melanin-concentrating hormone(MCH) is known to be an important regulator for feeding and
energy balance. MCH was recently reported to stimulate water intake independent of food
intake. The purpose of the present study isto examine the dipsogenic response of MCH ... Cited by 4 - Related articles - All 5 versions
B Guesdon, E Paradis, P Samson, D … - American Journal of …, 2009 - Am Physiological Soc The brain melanin-concentrating hormone (MCH) system represents an anabolic system involved
in energy balance regulation through influences exerted on the homeostatic and nonhomeostatic
controls of food intake and energy expenditure. The present study was designed to further ... Cited by 4 - Related articles - All 3 versions
AK Gerdin, VV Surve, M Jönsson, M Bjursell, M … - … and Biophysical Research …, 2006 - Elsevier Using the mouse as a model organism in pharmaceutical research presents unique advantages
as its physiology in many ways resembles the human physiology, it also has a relatively short
generation time, low breeding and maintenance costs, and is available in a wide variety ... Cited by 6 - Related articles - All 6 versions
- ►diabetesjournals.org JY Jeon, RL Bradley, EG Kokkotou, FE Marino, X Wang … - Diabetes, 2006 - Am Diabetes Assoc Ablation of the hypothalamic peptide, melanin-concentrating hormone (MCH), leads to a lean
phenotype and resistance to diet-induced obesity. Observation of MCH −/− mice at older ages
suggested that these effects persist in mice >1 year old. Leanness secondary to caloric ... Cited by 14 - Related articles - BL Direct - All 4 versions
BE Hawes, B Green, K O'Neill, S Fried, MG Arreaza, … - Obesity research, 2004 - ncbi.nlm.nih.gov OBJECTIVE: To identify and functionally characterize single-nucleotide polymorphisms
(SNPs) in melanin-concentrating hormone (MCH)-R1 and -R2. RESEARCH METHODS AND
PROCEDURES: The entire coding regions and intron/exon splice junction regions of ... Cited by 5 - Related articles - BL Direct - All 3 versions
Y Saito, H Nagasaki - Results and problems in cell differentiation, 2008 - ncbi.nlm.nih.gov Melanin-concentrating hormone (MCH) is a neuropeptide that was originally isolated from salmon
pituitary where it causes pigment aggregation. MCH is also abundantly present in mammalian
neurons and expressed in the lateral hypothalamus and zona incerta, brain regions that ... Cited by 7 - Related articles
M Bjursell, E Egecioglu, AK Gerdin, L Svensson, J … - … and Biophysical Research …, 2005 - Elsevier The hypothalamic peptide melanin-concentrating hormone (MCH) and the gastric hormone ghrelin
take part in the regulation of energy homeostasis and stimulate food intake. In the present
study, ghrelin was administered centrally to MCH-receptor knockout (MCHr KO) mice. ... Cited by 20 - Related articles - All 4 versions
