D Liu, W Zhen, Z Yang, JD Carter, H Si, KA Reynolds - Diabetes, 2006 - Am Diabetes Assoc Although genistein, a soy isoflavone, has beneficial effects on various tissues, it is unclear whether
it plays a role in physiological insulin secretion. Here, we present evidence that genistein increases
rapid glucose-stimulated insulin secretion (GSIS) in both insulin-secreting cell lines ... Cited by 34 - Related articles - BL Direct - All 6 versions
T Szkudelski, L Nogowski, E Pruszyńska-Oszmałek, … - Journal of steroid …, 2005 - Elsevier The isoflavones – genistein and daidzein – compounds found in high concentrations in soy play
an important role in prevention of many diseases and affect some metabolic pathways. In the
performed experiment it was demonstrated that genistein (5 mg/kg bw) administered ... Cited by 21 - Related articles - All 3 versions
P Mackowiak, L Nogowski, KW … - Journal of Receptors and …, 1999 - informahealthcare.com The experiments were carried out on ovariectomized Wistar rats Their livers were perhsed with
lbasic perhsion medium (BPM) or BPM supplemented with isoflavone genistein. insulin or combination
of the two factors. The obtained results support the hypothesis that genistein influences ... Cited by 14 - Related articles - BL Direct - All 4 versions
RL Sorenson, TC Brelje, C Roth - Endocrinology, 1994 - Endocrine Soc Page 1. 0013-7227/94/1344-1975$03.co/O Endocrinology Copyright 0 1994 by The Endoerine
Society Vol. 134, No. 4 Printed in USA Effect of Tyrosine Kinase Inhibitors on Islets of Langerhans:
Evidence for Tyrosine Kinases in the Regulation of Insulin Secretion* ... Cited by 54 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] JC Jonas, TD Plant, P Gilon, P Detimary, … - British journal of …, 1995 - pubmedcentral.nih.gov 1 Islets from normal mice were used to test the acute effects of genistein, a potent tyrosine kinase
inhibitor, on stimulus-secretion couplingin pancreatic P-cells. 2 Genistein produced a
concentration-dependent (10-100I1M), reversible, increase of insulin release. This effect ... Cited by 45 - Related articles - BL Direct - All 5 versions
KM Burvall, L Palmberg, K Larsson - Molecular and cellular biochemistry, 2002 - Springer Genistein is often used as an inhibitor of tyrosine kinases. A less studied side effect of genistein
is an inhibition of cyclic AMP- phosphodiesterase (cAMP-PDE) activity resulting in increased
cAMP accumulation. The effect of genistein on intracellular cAMP-levels, basal and ... Cited by 13 - Related articles - BL Direct - All 4 versions
JS Lee - Life sciences, 2006 - Elsevier In the current study, the effect of soy protein and genistein, one of the main isoflavones in
soybeans, on blood glucose, lipid profile, and antioxidant enzyme activities in streptozotocin
(STZ)-induced diabetic rats was investigated. Male Sprague–Dawley rats were divided ... Cited by 39 - Related articles - All 7 versions
K Szkudelska, L Nogowski, T Szkudelski - Journal of Steroid Biochemistry and …, 2000 - Elsevier Genistein is a phytoestrogen found in several plants eaten by humans and food-producing animals
and exerting a wide spectrum of biological activity. In this experiment, the impact of genistein
on lipogenesis and lipolysis was studied in isolated rat adipocytes. Incubation of the cells ( ... Cited by 51 - Related articles - BL Direct - All 5 versions
E de Arruda Oliveira, LM Gomes Cheim, RV Veloso, … - Nutrition, 2008 - Elsevier Rats fed a soybean flour diet had a lower final body weight, epididymal fat pad, carcass fat
content, and liver glycogen level. The serum glucose concentrations in the basal and fed states
and the area under the glucose curves during the glucose tolerance test were not ... Cited by 3 - Related articles - All 12 versions
