PA Goldberg, R Weiss, RJ McCrimmon, EV Hintz, JD … - Diabetes, 2006 - Am Diabetes Assoc Hypoglycemia-associated autonomic failure (HAAF) occurs commonly in patients with longstanding
diabetes, placing affected patients at increased risk for severe hypoglycemia. Previous studies
have suggested that hypoglycemia-induced hypercortisolemia may be responsible for ... Cited by 11 - Related articles - BL Direct - All 6 versions
B Raju, VP McGregor, PE Cryer - Diabetes, 2003 - Am Diabetes Assoc The concept of hypoglycemia-associated autonomic failure (HAAF) in diabetes posits that recent
antecedent iatrogenic hypoglycemia causes both defective glucose counterregulation (by reducing
the epinephrine response in the setting of an absent glucagon response) and ... Cited by 22 - Related articles - BL Direct - All 4 versions
- ►nih.gov RJ McCrimmon, Z Song, H Cheng, EC … - Journal of Clinical …, 2006 - Am Soc Clin Investig Recurrent episodes of hypoglycemia impair sympathoadrenal counterregulatory responses
(CRRs) to a subsequent episode of hypoglycemia. For individuals with type 1 diabetes, this markedly
increases (by 25-fold) the risk of severe hypoglycemia and is a major limitation to optimal ... Cited by 29 - Related articles - BL Direct - All 11 versions
CG Fanelli, S Pampanelli, F Porcellati - Diabetes, nutrition & metabolism(Testo …, 2002 - cat.inist.fr Cognitive function in hypoglycaemia. CG FANELLI, S PAMPANELLI, F PORCELLATI
Diabetes, nutrition & metabolism(Testo stampato) 15:55, 367-372, Kurtis, 2002.
Système nerveux central pathologie; Central nervous system ... Cited by 3 - Related articles - BL Direct - All 2 versions
DA Sandoval, L Ping, RA Neill, S Morrey, SN Davis - Diabetes, 2004 - Am Diabetes Assoc We previously determined that both antecedent hypoglycemia and elevated cortisol levels blunt
neuroendocrine and metabolic responses to subsequent hypoglycemia in conscious, unrestrained
rats. The adrenal steroid dehydroepiandrosterone sulfate (DHEA-S) has been shown in ... Cited by 5 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org DE Flanagan, T Keshavarz, ML Evans, S Flanagan, X … - Diabetes, 2003 - Am Diabetes Assoc We have explored the role of individual elements of the hypothalamic pituitary adrenal axis on
the pathogenesis of hypoglycemia-associated autonomic failure. Five groups of male
Sprague-Dawley rats were used. Control animals had 3 days of sham treatment followed ... Cited by 39 - Related articles - BL Direct - All 6 versions
- ►physiology.org KE Inouye, O Chan, JTY Yue, SG … - American Journal of …, 2005 - Am Physiological Soc Epinephrine, norepinephrine, and corticosterone responses to hypoglycemia are impaired in
diabetic rats. Recurrent hypoglycemia further diminishes epinephrine responses. This study
examined the sympathoadrenal system and hypothalamo-pituitary-adrenal axis for ... Cited by 14 - Related articles - All 4 versions
- ►physiology.org DA Sandoval, L Ping, RA Neill, B Gong, K … - American Journal of …, 2005 - Am Physiological Soc The aim of this study was to determine whether activation of central type II glucocorticoid receptors
can blunt autonomic nervous system counterregulatory responses to subsequent
hypoglycemia. Sixty conscious unrestrained Sprague-Dawley rats were studied during 2- ... Cited by 14 - Related articles - All 4 versions
- ►endojournals.org KE Inouye, JTY Yue, O Chan, T Kim, EM Akirav, E Park, … - Endocrinology, 2006 - Endocrine Soc Untreated diabetic rats show impaired counterregulation against hypoglycemia. The blunted
epinephrine responses are associated with reduced adrenomedullary tyrosine hydroxylase
(TH) mRNA levels. Recurrent hypoglycemia further impairs epinephrine ... Cited by 6 - Related articles - BL Direct - All 4 versions
AM Robinson, HM Parkin, IA Macdonald, RB … - Clinical science(1979), 1995 - cat.inist.fr 1. Recent hypoglycaemia reduces the counter-regulatory and symptomatic response to the next
episode of hypoglycaemia. This study was designed to determine whether antecedent
hypoglycaemia(a) affected the sympathoadrenal response to other stimuli(postural ... Cited by 8 - Related articles - BL Direct - All 9 versions
