CEN Reiter, X Wu, L Sandirasegarane, M … - Diabetes, 2006 - Am Diabetes Assoc Diabetic retinopathy is characterized by early onset of neuronal cell death. We
previously showed that insulin mediates a prosurvival pathway in retinal neurons
and that normal retina expresses a highly active basal insulin receptor/Akt ... Cited by 33 - Related articles - BL Direct - All 5 versions
- ►jneurosci.org X Yi, M Schubert, NS Peachey, K Suzuma, DJ … - Journal of Neuroscience, 2005 - Soc Neuroscience Insulin receptor substrates (Irs-proteins) integrate signals from the insulin
and insulin-like growth factor-1 (IGF1) receptors with other processes to
control cellular growth, function, and survival. Here, we show that Irs2 ... Cited by 21 - Related articles - All 7 versions
CEN Reiter, X Wu, L Sandirasegarane, M … - DIABETES, 2006 - Am Diabetes Assoc Diabetic retinopathy is characterized by early onset of neuronal cell death. We
previously showed that insulin mediates a prosurvival pathway in retinal neurons
and that normal retina expresses a highly active basal insulin recep- ... Related articles
- ►jbc.org A Rajala, M Tanito, YZ Le, CR Kahn, RVS … - Journal of Biological Chemistry, 2008 - ASBMB Insulin receptor (IR) signaling provides a trophic signal for transformed
retinal neurons in culture, but the role of IR activity in vivo is unknown. We
previously reported that light causes increased tyrosine phosphorylation of ... Cited by 7 - Related articles - All 4 versions
A Rajala, RE Anderson, JX Ma, J Lem, MR Al- … - Journal of Biological Chemistry, 2007 - ASBMB We have shown previously that phosphoinositide 3-kinase in the retina is
activated in vivo through light-induced tyrosine phosphorylation of the insulin
receptor (IR). The light effect is localized to photoreceptor neurons and ... Cited by 7 - Related articles - All 5 versions
- ►physiology.org CEN Reiter, L Sandirasegarane, EB Wolpert, M … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc Insulin receptor (IR) signaling cascades have been studied in many tissues, but
retinal insulin action has received little attention. Retinal IR signaling and
activity were investigated in vivo in rats that were freely fed, fasted, or ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►cjb.net G Li, RE Anderson, H Tomita, R Adler, X Liu, … - Journal of Neuroscience, 2007 - neuro.cjb.net The Akt kinases mediate cell survival through phosphorylation and inactivation
of apoptotic machinery components. Akt signaling provides a trophic signal for
transformed retinal neurons in culture, but the in vivo role of Akt ... Cited by 18 - Related articles - All 4 versions
RVS Rajala, ME McClellan, JD Ash, RE … - Journal of Biological Chemistry, 2002 - ASBMB Recently, we have shown that phosphoinositide 3-kinase (PI3K) in bovine rod
outer segment (ROS) is activated in vitro by tyrosine phosphorylation of the
C-terminal tail of the insulin receptor (Rajala, RVS, and Anderson, RE ... Cited by 36 - Related articles - BL Direct - All 6 versions
RVS Rajala, ME McClellan, MD Chan, L … - Biochemistry, 2004 - pubs.acs.org This work was supported by grants from the National Institutes of Health (Grants
EY00871, EY04149, EY12190, DK59599, and RR17703), Research to Prevent Blindness
Inc., New York, NY, The Foundation Fighting Blindness, Baltimore, MD, and ... Cited by 14 - Related articles - BL Direct - All 4 versions
CEN Reiter, TW Gardner - Progress in retinal and eye research, 2003 - Elsevier Insulin action regulates the metabolic functions of the classically
insulin-responsive tissues: liver, adipose, and skeletal muscle. Evidence also
suggests that insulin acts on neural tissue and can modulate neural ... Cited by 23 - Related articles - All 3 versions
