ED Labonté, RJ Kirby, NM Schildmeyer, AM Cannon, … - Diabetes, 2006 - Am Diabetes Assoc Postprandial hyperglycemia is an early indicator of abnormality in glucose metabolism leading
to type 2 diabetes. However, mechanisms that contribute to postprandial hyperglycemia have
not been identified. This study showed that mice with targeted inactivation of the group 1B ... Cited by 15 - Related articles - BL Direct - All 6 versions
M Rouault, C Le Calvez, E Boilard, F Surrel, A … - Biochemistry, 2007 - faculty.washington.edu ABSTRACT: To date, 12 secreted phospholipases A2 (sPLA2s) have been identified in the mouse
species and divided into three structural collections (I/II/V/X, III, and XII). On the basis of their
different molecular properties and tissue distributions, each sPLA2 is likely to exert ... Cited by 15 - Related articles - View as HTML - All 5 versions
- ►physiology.org KW Huggins, AC Boileau, DY Hui - American Journal of …, 2002 - Am Physiological Soc Group 1B phospholipase A 2 (PLA 2 ) is an abundant lipolytic enzyme that is well characterized
biochemically and structurally. Because of its high level of expression in the pancreas, it has
been presumed that PLA 2 plays a role in the digestion of dietary lipids, but in vivo data ... Cited by 33 - Related articles - BL Direct - All 5 versions
- ►nih.gov I Munoz-Sanjuan, AH Brivanlou - Molecular and Cellular Biology, 2005 - Am Soc Microbiol The secreted phospholipases A 2 (sPLA 2 s) comprise a family of small secreted proteins with
the ability to catalyze the generation of bioactive lipids through glycophospholipid
hydrolysis. Recently, a large number of receptor proteins and extracellular binding ... Cited by 7 - Related articles - All 5 versions
- ►jbc.org M Ohtsuki, Y Taketomi, S Arata, S Masuda, Y … - Journal of Biological …, 2006 - ASBMB In an effort to elucidate the functions of secreted phospholipase A 2 (sPLA 2 ) enzymes in
vivo, we generated transgenic (Tg) mice for group V sPLA 2 (sPLA 2 -V) and group X sPLA 2
(sPLA 2 -X), which act potently on phosphatidylcholine in vitro.We found that sPLA 2 -V ... Cited by 17 - Related articles - All 7 versions
S Masuda, K Yamamoto, T Hirabayashi, Y … - The Biochemical …, 2008 - ncbi.nlm.nih.gov Human sPLA2-III [group III secreted PLA2 (phospholipase A2)] is an atypical sPLA2 isoenzyme
that consists of a central group III sPLA2 domain flanked by unique N- and C-terminal
domains. In the present study, we found that sPLA2-III is expressed in neuronal cells, ... Cited by 10 - Related articles - BL Direct - All 5 versions
M Kimura-Matsumoto, Y Ishikawa, K Komiyama, T … - Atherosclerosis, 2008 - Elsevier Secretory phospholipase A2s (sPLA2s) contribute to the hydrolysis of phospholipid. Among
them, sPLA2-IIA, -V, and -X have been regarded as enhancers of lipid accumulation in arterial
intima. However, the distribution and production of the other types of sPLA2 in human ... Cited by 12 - Related articles - All 11 versions
- ►jbc.org B Balestrieri, VW Hsu, H Gilbert, CC Leslie, WK … - Journal of Biological …, 2006 - ASBMB We have previously reported that group V secretory phospholipase A 2 (sPLA 2 ) amplifies the
action of cytosolic phospholipase A 2 (cPLA 2 ) in regulating eicosanoid biosynthesis by mouse
peritoneal macrophages stimulated with zymosan (Satake, Y., Diaz, BL, Balestrieri, B., ... Cited by 36 - Related articles - BL Direct - All 6 versions
- ►jbc.org M Murakami, S Masuda, S Shimbara, Y Ishikawa, T … - Journal of Biological …, 2005 - ASBMB Human group III secreted phospholipase A 2 (sPLA 2 -III) consists of a central group III sPLA
2 domain flanked by unique N- and C-terminal domains. We found that the sPLA 2 domain alone
was sufficient for its catalytic activity and for its prostaglandin E 2 (PGE 2 )-generating ... Cited by 24 - Related articles - All 6 versions
C Deregnaucourt, J Schrevel - Journal of Biological Chemistry, 2000 - ASBMB Secreted phospholipases A 2 (sPLA 2 s) from snake and insect venoms and from mammalian
pancreas are structurally related enzymes that have been associated with several toxic,
pathological, or physiological processes. We addressed the issue of whether toxic sPLA 2 ... Cited by 14 - Related articles - BL Direct - All 3 versions