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Scholar Results 1 - 10 of about 101 related to Chida: Combined interleukin-6 and interleukin-1 deficiency causes obesity in young mice. (0.09 sec) 

Combined interleukin-6 and interleukin-1 deficiency causes obesity in young mice


D Chida, T Osaka, O Hashimoto, Y Iwakura - Diabetes, 2006 - Am Diabetes Assoc
Proinflammatory cytokines including interleukin (IL)-1 and IL-6 exert
pleiotropic effects on the neuro-immuno-endocrine system. Previously, we showed
that IL-1 receptor antagonist–deficient (IL-1Ra −/− ) mice show a ...
Cited by 25 - Related articles - BL Direct - All 5 versions

Mature-onset obesity in interleukin-1 receptor I knockout mice

- shouxi.net
MC García, I Wernstedt, A Berndtsson, M Enge … - Diabetes, 2006 - Am Diabetes Assoc
Interleukin-1 (IL-1) is a major mediator of inflammation that exerts its
biological activities through the IL-1 type I receptor (IL-1RI). The body
weights of IL-1RI −/− mice of both sexes started to deviate from those ...
Cited by 36 - Related articles - BL Direct - All 7 versions

Interleukin-1 system gene polymorphisms are associated with fat mass in young men

- endojournals.org
L Strandberg, M Lorentzon, A Hellqvist, S … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc
Context: There is growing evidence for interactions between the regulation of
body fat and the immune system. Studies of knockout mice indicate that IL-1 has
an antiobesity effect. ... Objective: The objective of the study was to ...
Cited by 12 - Related articles - BL Direct - All 9 versions

Combined Interleukin-6 and Interleukin-1 Deficiency Causes Obesity in Young Mice


TO Dai Chida, O Hashimoto, Y Iwakura - 糖尿病学杂志, 2006 - journal.shouxi.net
Proinflammatory cytokines including interleukin (IL)-1 and IL-6 exert
pleiotropic effects on the neuro-immuno-endocrine system. Previously, we showed
that IL-1 receptor antagonisteCdeficient (IL-1RaeC/eC) mice show a lean ...
Related articles - Cached

Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency

- pnas.org
EP Zorrilla, M Sanchez-Alavez, S Sugama, M … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences
Circulating levels of the cytokine interleukin 18 (IL-18) are elevated in
obesity. Here, we show that administration of IL-18 suppresses appetite, feed
efficiency, and weight regain in food-deprived male and female C57BL/6J ...
Cited by 16 - Related articles - BL Direct - All 8 versions

Decreased Fat Mass in Interleukin-1 Receptor Antagonist–Deficient Mice


E Somm, E Henrichot, A Pernin, CE Juge- … - Diabetes, 2005 - Am Diabetes Assoc
Interleukin (IL)-1 is a regulator of inflammation but is also implicated in the
control of energy homeostasis. Because the soluble IL-1 receptor antagonist
(IL-1Ra) is markedly increased in the serum of obese patients and is ...
Cited by 30 - Related articles - BL Direct - All 5 versions

GM-CSF action in the CNS decreases food intake and body weight

- nih.gov
JA Reed, DJ Clegg, KB Smith, EG Tolod-Richer … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig
Many proinflammatory cytokines, such as leptin, play key roles in dynamic
regulation of energy expenditure and food intake. The present work tested a role
for the proinflammatory cytokine GM-CSF. Central but not peripheral ...
Cited by 17 - Related articles - BL Direct - All 10 versions

[PDF] Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance


MG Netea, LAB Joosten, E Lewis, DR Jensen, … - Nature - 140.116.93.232
Here we report the presence of hyperphagia, obesity and insulin resistance in
knockout mice deficient in IL-18 or IL-18 receptor, and in mice transgenic for
expression of IL-18 binding protein. Obesity of Il18Ā/Ā mice resulted ...
Cited by 59 - Related articles - View as HTML - BL Direct - All 14 versions

IL-1 plays an important role in lipid metabolism by regulating insulin levels under …

- rupress.org
T Matsuki, R Horai, K Sudo, Y Iwakura - Journal of Experimental Medicine, 2003 - jem.rupress.org
IL-1 is a proinflammatory cytokine that plays important roles in inflammation.
However, the role of this cytokine under physiological conditions is not known
completely. In this paper, we analyzed the role of IL-1 in maintaining body ...
Cited by 80 - Related articles - BL Direct - All 6 versions

IL6 and IL1B polymorphisms are associated with fat mass in older men: the MrOS Study …


L Strandberg, D Mellström, Ö Ljunggren, E … - Obesity, 2008 - nature.com
There is growing evidence that immune functions are linked to the regulation of
body fat. Our studies of knockout mice indicate that both endogenous interleukin
(IL)-6 and IL-1 can suppress mature-onset obesity. We now investigated ...
Cited by 6 - Related articles - All 2 versions


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