- ►diabetesjournals.org DJ Clegg, LM Brown, SC Woods, SC Benoit - Diabetes, 2006 - Am Diabetes Assoc Males have proportionally more visceral fat and are more likely to develop
complications associated with obesity than females, and the male brain is
relatively more sensitive to the catabolic action of insulin and less ... Cited by 83 - Related articles - BL Direct - All 5 versions
DJ Clegg, CA Riedy, KAB Smith, SC Benoit, … - Diabetes, 2003 - Am Diabetes Assoc The distribution of fat in the body differs between the male and female sexes
and is associated with the relative secretion of the two “adiposity”
hormones leptin and insulin. We now report that the brains of male and ... Cited by 82 - Related articles - BL Direct - All 5 versions
L Asarian, N Geary - Hormones and Behavior, 2002 - Elsevier Hypothalamic–pituitary–gonadal axis function strongly influences feeding and
body weight in cycling females in many species. To test the sufficiency of
cyclic variations in plasma estradiol to reproduce normal patterns of ... Cited by 67 - Related articles - BL Direct - All 4 versions
DJ Clegg, LM Brown, JM Zigman, CJ Kemp, AD … - Diabetes, 2007 - Am Diabetes Assoc Ghrelin, the only known orexigenic gut hormone, is secreted mainly from the
stomach, increases with fasting and before meal initiation in humans and rats,
and increases food intake after central or peripheral administration. To ... Cited by 25 - Related articles - BL Direct - All 14 versions
Q Gao, G Mezei, Y Nie, Y Rao, CS Choi, I … - Nature medicine, 2006 - nature.com Metabolic hormones, such as leptin, alter the input organization of hypothalamic
circuits 1, 2, 3 , resulting in increased pro-opiomelanocortin (POMC) tone,
followed by decreased food intake and adiposity. The gonadal steroid ... Cited by 52 - Related articles - BL Direct - All 4 versions
L Asarian, N Geary - Philosophical Transactions of the Royal Society B: …, 2006 - rstb.royalsocietypublishing.org Several sex differences in eating, their control by gonadal steroid hormones and
their peripheral and central mediating mechanisms are reviewed. Adult female
rats and mice as well as women eat less during the peri-ovulatory phase of ... Cited by 54 - Related articles - BL Direct - All 8 versions
M Hallschmid, C Benedict, B Schultes, HL … - Diabetes, 2004 - Am Diabetes Assoc Insulin acts in the central nervous system to reduce food intake and body weight
and is considered a major adiposity signal. After intranasal administration,
insulin enters the cerebrospinal fluid compartment and alters brain ... Cited by 59 - Related articles - BL Direct - All 10 versions
- ►ebmonline.org SC Woods, K Gotoh, DJ Clegg - Experimental Biology and Medicine, 2003 - SEBM The world is experiencing an epidemic of obesity and its concomitant health
problems. One implication is that the normally robust negative feedback system
that controls energy homeostasis must be responding to different inputs ... Cited by 51 - Related articles - BL Direct - All 3 versions
S Diano, SP Kalra, H Sakamoto, TL Horvath - Brain research, 1998 - Elsevier This study was undertaken to reveal whether integration of the peripheral
signals, leptin and estradiol, that convey information on the metabolic state
and gonadal function, respectively, might occur in the same hypothalamic ... Cited by 41 - Related articles - All 4 versions
BJ Hrupka, GP Smith, N Geary - Physiology & behavior, 2002 - ncbi.nlm.nih.gov To investigate further the site where estradiol (E(2)) inhibits food intake, we
tested the effects on feeding of subcutaneous and intrahypothalamic implants of
10% E(2) benzoate in cholesterol (CHOL) or CHOL alone. E(2) was implanted ... Cited by 14 - Related articles - All 3 versions
