MV Li, B Chang, M Imamura, N Poungvarin, L … - Diabetes, 2006 - Am Diabetes Assoc We report here a novel mechanism for glucose-mediated activation of carbohydrate
response element binding protein (ChREBP), a basic helix-loop-helix/leucine
zipper (bHLH/ZIP) transcription factor of Mondo family that binds to ... Cited by 34 - Related articles - BL Direct - All 5 versions
NG Tsatsos, HC Towle - Biochemical and Biophysical Research …, 2006 - Elsevier Carbohydrate response element binding protein (ChREBP) is a transcription factor
that mediates glucose-responsive changes in gene expression in hepatocytes. In
the current model for glucose regulation, inhibition of ChREBP in low ... Cited by 28 - Related articles - All 5 versions
- ►jlr.org G da Silva Xavier, GA Rutter, F Diraison, C … - The Journal of Lipid Research, 2006 - ASBMB Pancreatic ß-cell dysfunction is central to the pathogenesis of type 2 diabetes
and may involve secretory failure through glucolipotoxity. The relative
importance of the transcription factors carbohydrate-responsive element ... Cited by 20 - Related articles - BL Direct - All 3 versions
- ►nih.gov L Ma, YY Sham, KJ Walters, HC Towle - Nucleic acids research, 2007 - Oxford Univ Press The carbohydrate response element (ChoRE) is a cis-acting sequence found in the
promoters of genes induced transcriptionally by glucose. The ChoRE is composed
of two E box-like motifs that are separated by 5 bp and is recognized by ... Cited by 19 - Related articles - BL Direct - All 8 versions
L Ma, LN Robinson, HC Towle - Journal of Biological Chemistry, 2006 - ASBMB In mammals, glucose-regulated gene expression has been best characterized in the
liver, where increased glucose metabolism induces transcription of genes
encoding enzymes involved in de novo lipogenesis. ChREBP and Mlx dimerize ... Cited by 42 - Related articles - All 6 versions
- ►jbc.org AK Stoeckman, L Ma, HC Towle - Journal of Biological Chemistry, 2004 - ASBMB The expression of genes encoding enzymes involved in de novo triglyceride
synthesis (lipogenesis) is transcriptionally induced in the liver in response to
increased glucose metabolism. The carbohydrate response element-binding ... Cited by 71 - Related articles - BL Direct - All 5 versions
- ►physiology.org [PDF] K Iizuka, B Miller, K Uyeda - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc 28 articles, 16 of which you can access free at: This article cites
http://ajpendo.physiology.org/cgi/content/full/291/2/E358#BIBL ... 1 other
HighWire hosted article: This article has been cited by Cited by 27 - Related articles - BL Direct - All 4 versions
H Wang, CB Wollheim - Journal of Biological Chemistry, 2002 - ASBMB There is controversy whether or not upstream stimulatory factors (USF) regulate
the glucose responsiveness of L-pyruvate kinase (L-PK) promoter activity in
hepatocytes. It has been suggested that USF-2 is required for glucose ... Cited by 49 - Related articles - BL Direct - All 6 versions
- ►physiology.org J Jason Collier, P Zhang, KB Pedersen, SJ … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc Increased glucose flux generates metabolic signals that control transcriptional
programs through poorly understood mechanisms. Previously, we demonstrated a
necessity in hepatocytes for c-Myc in the regulation of a prototypical ... Cited by 8 - Related articles - BL Direct - All 9 versions
L Ma, NG Tsatsos, HC Towle - Journal of Biological Chemistry, 2005 - ASBMB Enzymes required for de novo lipogenesis are induced in mammalian liver after a
meal high in carbohydrates. In addition to insulin, increased glucose metabolism
initiates an intracellular signaling pathway that transcriptionally ... Cited by 52 - Related articles - All 8 versions
