- ►diabetesjournals.org MD López-Avalos, VF Duvivier-Kali, G Xu, S Bonner- … - Diabetes, 2006 - Am Diabetes Assoc The ubiquitin-proteasome pathway is crucial for protein turnover. Part of the pathway involves
deubiquitination, which is carried out by cystein proteases known as ubiquitin COOH-terminal
hydrolases. The isoform Uch-L1 was found to be present in large amounts in rat islets by ... Cited by 9 - Related articles - BL Direct - All 4 versions
- ►jbc.org M Kawaguchi, K Minami, K Nagashima, S Seino - Journal of Biological …, 2006 - ASBMB Insulin secretion from pancreatic -cells occurs by sequential cellular processes, including glucose
metabolism, electrical activity, Ca 2+ entry, and regulated exocytosis. Abnormalities in any of
these functions can impair insulin secretion. In the present study, we demonstrate that ... Cited by 8 - Related articles - BL Direct - All 6 versions
- ►physiology.org FF Yan, CW Lin, EA Cartier, SL … - American Journal of …, 2005 - Am Physiological Soc ATP-sensitive potassium (K ATP ) channels of pancreatic -cells mediate glucose-induced insulin
secretion by linking glucose metabolism to membrane excitability. The number of plasma membrane
K ATP channels determines the sensitivity of -cells to glucose stimulation. The K ATP ... Cited by 16 - Related articles - BL Direct - All 6 versions
- ►jbc.org K Kitiphongspattana, CE Mathews, EH Leiter, HR … - Journal of Biological …, 2005 - ASBMB Metabolic labeling studies were conducted in freshly isolated mouse islets and a -cell line
(MIN6) to examine the effects of proteasome inhibition on glucose-stimulated (pro)insulin synthesis
and secretion. Glucose-stimulated (pro)insulin synthesis, as determined by the ... Cited by 27 - Related articles - All 5 versions
C IONESCU-TÎRGOVIŞTE, C GUJA - paulescu.ro Based on our clinical and epidemiological data, we have sustained for a long time the unitary
character of the various phenotypes of the diabetic syndrome. In this paper, we add several arguments
sustaining that the unitary character of diabetes is related to a common primary defect in ... Related articles - View as HTML - All 2 versions
Z Ma - diss.kib.ki.se This thesis attempts to further clarify mechanisms behind the negative effects of over- stimulation
and the beneficial effect of ß-cell rest. For this purpose diazoxide - opener of K+-ATP
channels, which reversibly inhibits glucose-induced insulin secretion, was used as a ... Related articles
T Hartley, J Brumell, A Volchuk - American Journal of Physiology- …, 2009 - Am Physiological Soc Protein degradation in eukaryotic cells is mediated primarily by the ubiquitin-proteasome system
and autophagy. Turnover of protein aggregates and other cytoplasmic components, including
organelles, is another function attributed to autophagy. The ubiquitin-proteasome system ... Cited by 1 - Related articles - All 3 versions
