- ►diabetesjournals.org K Hara, M Horikoshi, H Kitazato, C Ito, M Noda, J … - Diabetes, 2006 - Am Diabetes Assoc Hepatocyte nuclear factor (HNF)-4α is a transcription factor known as a key molecule in the development
and functions of the β-cells. In a previously performed genome-wide scan of Japanese type 2
diabetic sibpairs, we observed linkage of type 2 diabetes to chromosome 20q12-q13, a ... Cited by 25 - Related articles - BL Direct - All 5 versions
DM Lehman, DK Richardson, CP Jenkinson, KJ Hunt, … - Diabetes, 2007 - Am Diabetes Assoc Common and rare variants of the hepatocyte nuclear factor 4α (HNF4A) gene have been associated
with type 2 diabetes and related traits in several populations suggesting the involvement of this
transcription factor in diabetes pathogenesis. Single nucleotide polymorphisms (SNPs) ... Cited by 12 - Related articles - BL Direct - All 5 versions
AM Bagwell, JL Bento, JC Mychaleckyj, BI Freedman, … - Diabetes, 2005 - Am Diabetes Assoc Hepatocyte nuclear factor 4α (HNF4A), the gene for the maturity-onset diabetes of the young
type 1 monogenic form of type 2 diabetes, is within the type 2 diabetes–linked region on chromosome
20q12-q13.1 and, consequently, is a positional candidate gene for type 2 diabetes in the ... Cited by 32 - Related articles - All 5 versions
M Vaxillaire, C Dina, S Lobbens, A Dechaume, V … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 440–444 DOI 10.1007/s00125-004-1665-3 SHORT
COMMUNICATION M. Vaxillaire . C. Dina . S. Lobbens . A. Dechaume . V.
Vasseur-Delannoy . N. Helbecque . G. Charpentier . P. Froguel Effect ... Cited by 27 - Related articles - All 3 versions
- ►diabetesjournals.org YL Muller, AM Infante, RL Hanson, L Love-Gregory, W … - Diabetes, 2005 - Am Diabetes Assoc Single nucleotide polymorphisms (SNPs) within the hepatocyte nuclear factor 4α (HNF4α) gene
are associated with type 2 diabetes in Finns and Ashkenazi Jews. Previous studies in both populations
have reported linkage to type 2 diabetes near the HNF4α locus on chromosome ... Cited by 37 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org CM Damcott, N Hoppman, SH Ott, LJ Reinhart, J Wang, … - Diabetes, 2004 - Am Diabetes Assoc Hepatocyte nuclear factor 4-α (HNF4A) is a transcription factor located on chromosome 20q13
that regulates expression of genes involved in glucose metabolism and homeostasis.
Recently, two groups independently identified single nucleotide polymorphism (SNPs) in ... Cited by 54 - Related articles - BL Direct - All 6 versions
K Wanic, MT Malecki, PP Wolkow, T Klupa, J … - Diabetes and Metabolism, 2006 - Elsevier Recently, several association studies of type 2 diabetes mellitus (T2DM) and the hepatocyte
nuclear factor (HNF)-4α gene were reported with conflicting results. Our aim was to search for
association between two polymorphisms of HNF-4α and T2DM in Polish Caucasians. The ... Cited by 11 - Related articles - All 3 versions
H Ræder, L Bjørkhaug, S Johansson, K Mangseth, JV … - Diabetes, 2006 - Am Diabetes Assoc Variants in hepatocyte nuclear factor (HNF)-4α cause maturity-onset diabetes of the young, type
1 (MODY1) and may also be risk factors for type 2 diabetes. We sequenced the HNF4A gene
of 95 MODY3-negative probands from the Norwegian MODY Registry. We found three ... Cited by 19 - Related articles - BL Direct - All 4 versions
SK Hansen, CS Rose, C Glümer, T Drivsholm, K Borch- … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 452–458 DOI 10.1007/s00125-005-1671-0 ARTICLE SK
Hansen . CS Rose . C. Glümer . T. Drivsholm . K. Borch-Johnsen . T. Jørgensen . O. Pedersen .
T. Hansen Variation near the hepatocyte nuclear factor (HNF)-4α gene ... Cited by 42 - Related articles - All 5 versions
- ►tokushima-u.ac.jp [PDF] T Tanahashi, D Osabe, K Nomura, S Shinohara, H Kato … - Human genetics, 2006 - Springer Abstract Several linkage studies have predicted that human chromosome 20q is closely related
to type 2 diabetes, but there is no clear evidence that certain variant(s) or gene(s) have strong
effects on the disease within this region. To examine disease susceptibility variant in ... Cited by 15 - Related articles - BL Direct - All 5 versions
