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Scholar Results 1 - 10 of about 101 related to Aly: Multi-SNP Analysis of MHC Region. (0.12 sec) 

Multi-SNP Analysis of MHC Region

- diabetesjournals.org
TA Aly, E Eller, A Ide, K Gowan, SR Babu, HA … - Diabetes, 2006 - Am Diabetes Assoc
Technology has become available to cost-effectively analyze thousands of single
nucleotide polymorphisms (SNPs). We recently confirmed by genotyping a small
series of class I alleles and microsatellite markers that the extended ...
Cited by 25 - Related articles - BL Direct - All 6 versions

The haplotype structure of the human major histocompatibility complex

- harvard.edu [PDF] 
CA Alper, CE Larsen, DP Dubey, ZL Awdeh, DA … - Human immunology, 2006 - Elsevier
There is great interest in the use of single-nucleotide polymorphisms (SNPs) and
linkage disequilibrium (LD) analysis to localize human disease genes. The
results suggest that the human genome, including the major ...
Cited by 25 - Related articles - All 6 versions

[PDF] Conserved extended haplotypes discriminate HLA-DR3-homozygous Basque patients with …


JR Bilbao, B Calvo, AM Aransay, A Martin- … - Genes and immunity, 2006 - idi.harvard.edu
JR Bilbao1,2,9, B Calvo1,9, AM Aransay3, A Martin-Pagola1, G Pérez de
Nanclares1, TA Aly4, I Rica1, JC Vitoria1,5, S Gaztambide1,6, J Noble7, PR
Fain4, ZL Awdeh8, CA Alper8 and L Castan˜o1,5 1Endocrinology and Diabetes ...
Cited by 10 - Related articles - View as HTML - BL Direct - All 5 versions

Toward understanding MHC disease associations: partial resequencing of 46 distinct HLA …


WP Smith, Q Vu, SS Li, JA Hansen, LP Zhao, … - Genomics, 2006 - Elsevier
We carried out a resequencing project that examined 552 kb of sequence from each
of 46 individual HLA haplotypes representing a diversity of HLA allele types,
generating nearly 27 Mb of fully phased genomic sequence. Haplotype blocks ...
Cited by 22 - Related articles - All 4 versions

Genetic fixity in the human major histocompatibility complex and block size diversity in the …


V Romero, CE Larsen, JS Duke-Cohan, EA Fox, … - BMC genetics, 2007 - biomedcentral.com
Here, we present HLA-E allele haplotype association and population linkage
disequilibrium (LD) analysis within the ~1.3 Mb bounded by HLA-B/Cw and HLA-A to
increase the resolution of identified class I haplotypes. Through local ...
Cited by 7 - Related articles - Cached - All 7 versions

Analysis of single nucleotide polymorphisms identifies major type 1A diabetes locus …

- diabetesjournals.org
TA Aly, EE Baschal, MM Jahromi, MS Fernando … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—We found evidence for an association with type 1A diabetes (rs1233478,
P = 1.6 × 10 −23 , allelic odds ratio 2.0) in the UBD/MAS1L region, telomeric
of the classic MHC. We also observed over 99% conservation for up to 9 ...
Cited by 10 - Related articles - BL Direct - All 3 versions

HLA-DPB1* 0402 protects against type 1A diabetes autoimmunity in the highest risk …

- shouxi.net
EE Baschal, TA Aly, SR Babu, MS Fernando, L … - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE— A major goal in genetic studies of type 1A diabetes is prediction
of anti-islet autoimmunity and subsequent diabetes in the general population, as
>85% of patients do not have a first-degree relative with type 1A diabetes. ...
Cited by 15 - Related articles - BL Direct - All 5 versions

Human leukocyte antigen class IB and C loci contribute to type 1 diabetes (T1D) …


AM Valdes, HA Erlich, JA Noble - Human immunology, 2005 - Elsevier
Alleles of human leukocyte antigen (HLA) class II genes are well known to affect
susceptibility to type 1 diabetes (T1D), but less is known about the
contribution of HLA class I alleles to T1D susceptibility. In this study, ...
Cited by 36 - Related articles - All 3 versions

[CITATION] Extended


A Ide, SR Babu, DT Robles, T Wang, HA … - A1, B
Cited by 7 - Related articles

DPB1 alleles are associated with type 1 diabetes susceptibility in multiple ethnic groups

- diabetesjournals.org
TD Cruz, AM Valdes, A Santiago, T Frazer de … - Diabetes, 2004 - Am Diabetes Assoc
Genetic associations between type 1 diabetes and alleles at the HLA class II
locus DPB1 have been previously reported. Observed associations could be due to
variation in the DPB1 locus itself or to linkage disequilibrium (LD) ...
Cited by 17 - Related articles - BL Direct - All 4 versions


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