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Scholar Results 1 - 10 of about 101 related to Schoenborn: The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes. (0.11 sec) 

The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes

- shouxi.net
V Schoenborn, IM Heid, C Vollmert, A … - Diabetes, 2006 - Am Diabetes Assoc
Adipose triglyceride lipase (ATGL) was recently described to predominantly
perform the initial step in triglyceride hydrolysis and therefore seems to play
a pivotal role in the lipolytic catabolism of stored fat in adipose tissue. ...
Cited by 44 - Related articles - BL Direct - All 5 versions

Human adipose triglyceride lipase (PNPLA2) is not regulated by obesity and exhibits low in …


A Mairal, D Langin, P Arner, J Hoffstedt - Diabetologia, 2006 - Springer
Page 1. Diabetologia (2006) 49: 1629–1636 DOI 10.1007/s00125-006-0272-
x ARTICLE A. Mairal . D. Langin . P. Arner . J. Hoffstedt ...
Cited by 38 - Related articles - BL Direct - All 5 versions

The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-{ …

- physiology.org
JY Kim, K Tillison, JH Lee, DA Rearick, CM … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
The minimal adipose phenotype of hormone-sensitive lipase (HSL)-null mice
suggested that other hormonally responsive lipase(s) were present in adipocytes.
Recent studies have characterized a new adipose tissue triglyceride lipase, ...
Cited by 42 - Related articles - BL Direct - All 4 versions

Adipose Triglyceride Lipase

- diabetesjournals.org
EE Kershaw, JK Hamm, LAW Verhagen, O … - Diabetes, 2006 - Am Diabetes Assoc
Adipose triglyceride lipase (ATGL) is a recently described adipose-enriched
protein with triglyceride-specific lipase activity. ATGL shares the greatest
sequence homology with adiponutrin, a nutritionally regulated protein of ...
Cited by 77 - Related articles - BL Direct - All 6 versions

Isoproterenol, TNFα, and insulin downregulate adipose triglyceride lipase in 3T3-L1 …


S Kralisch, J Klein, U Lossner, M Bluher, R … - Molecular and Cellular Endocrinology, 2005 - Elsevier
Recently, adipose triglyceride lipase (ATGL, also called desnutrin and
calcium-independent phospholipase A2 [iPLA 2 ] ζ) was isolated as a novel
adipose-expressed triglyceride lipase which is downregulated in obesity and ...
Cited by 46 - Related articles - All 3 versions

Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members

- jlr.org
AC Lake, Y Sun, JL Li, JE Kim, JW Johnson, D … - The Journal of Lipid Research, 2005 - ASBMB
Adiponutrin and a related protein, adipocyte triglyceride lipase (ATGL; also
known as Desnutrin), were recently described as adipocyte-specific proteins with
lipid hydrolase activity. Using bioinformatics, we identified three ...
Cited by 65 - Related articles - BL Direct - All 7 versions

Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced …

- 166.111.30.161 [PDF] 
JA Villena, S Roy, E Sarkadi-Nagy, KH Kim, … - Journal of Biological Chemistry, 2004 - ASBMB
We have used rat cDNA microarrays to identify adipocyte-specific genes that
could play an important role in adipocyte differentiation or function. Here, we
report the cloning and identification of a 2.0-kb mRNA coding for a ...
Cited by 169 - Related articles - BL Direct - All 6 versions

Adipocyte lipases and defect of lipolysis in human obesity

- diabetesjournals.org
D Langin, A Dicker, G Tavernier, J Hoffstedt, … - Diabetes, 2005 - Am Diabetes Assoc
The mobilization of fat stored in adipose tissue is mediated by
hormone-sensitive lipase (HSL) and the recently characterized adipose
triglyceride lipase (ATGL), yet their relative importance in lipolysis is ...
Cited by 88 - Related articles - BL Direct - All 5 versions

ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells


E Smirnova, EB Goldberg, KS Makarova, L … - EMBO reports, 2006 - pubmedcentral.nih.gov
Lipid droplets (LDs), also called adiposomes, are found in many eukaryotic
cells, and are highly upregulated in lipid-storage cells, such as adipocytes.
The mechanism by which adiposomes and their component neutral lipids are ...
Cited by 53 - Related articles - BL Direct - All 5 versions

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

- meduni-graz.at [PDF] 
G Haemmerle, A Lass, R Zimmermann, G … - Science, 2006 - sciencemag.org
Fat tissue is the most important energy depot in vertebrates. The release of
free fatty acids (FFAs) from stored fat requires the enzymatic activity of
lipases. We showed that genetic inactivation of adipose triglyceride lipase ...
Cited by 169 - Related articles - BL Direct - All 11 versions


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