- ►diabetesjournals.org HKR Karlsson, M Ahlsén, JR Zierath, H … - Diabetes, 2006 - Am Diabetes Assoc Aberrant insulin signaling and glucose metabolism in skeletal muscle from type 2
diabetic patients may arise from genetic defects and an altered metabolic
milieu. We determined insulin action on signal transduction and glucose ... Cited by 26 - Related articles - BL Direct - All 5 versions
- ►shouxi.net HKR Karlsson, JR Zierath, S Kane, A Krook, … - Diabetes, 2005 - Am Diabetes Assoc AS160 is a newly described substrate for the protein kinase Akt that links
insulin signaling and GLUT4 trafficking. In this study, we determined the
expression of and in vivo insulin action on AS160 in human skeletal muscle. ... Cited by 78 - Related articles - All 5 versions
- ►shouxi.net A Deshmukh, VG Coffey, Z Zhong, AV Chibalin … - Diabetes, 2006 - Am Diabetes Assoc Skeletal muscle contraction stimulates multiple signaling cascades that govern a
variety of metabolic and transcriptional events. Akt/protein kinase B regulates
metabolism and growth/muscle hypertrophy, but contraction effects on this ... Cited by 44 - Related articles - BL Direct - All 5 versions
- ►shouxi.net K Bouzakri, HKR Karlsson, H Vestergaard, S … - Diabetes, 2006 - Am Diabetes Assoc Insulin-dependent diabetic recipients of successful pancreas allografts achieve
self-regulatory insulin secretion and discontinue exogenous insulin therapy;
however, chronic hyperinsulinemia and impaired insulin sensitivity ... Cited by 24 - Related articles - BL Direct - All 5 versions
- ►physiology.org JT Treebak, JB Birk, AJ Rose, B Kiens, EA … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc We investigated time- and intensity-dependent effects of exercise on
phosphorylation of Akt substrate of 160 kDa (AS160) in human skeletal muscle.
Subjects performed cycle exercise for 90 min (67% O 2 peak , n = 8), 20 min ... Cited by 26 - Related articles - BL Direct - All 4 versions
- ►shouxi.net JT Treebak, S Glund, A Deshmukh, DK Klein, … - Diabetes, 2006 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) is a heterotrimeric protein that regulates
glucose transport mediated by cellular stress or pharmacological agonists such
as 5-aminoimidazole-4-carboxamide 1 β-d-ribonucleoside (AICAR). AS160, a ... Cited by 82 - Related articles - BL Direct - All 7 versions
- ►physiology.org C Wilson, M Hargreaves, KF Howlett - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc The subcellular localization of insulin signaling proteins is altered by various
stimuli such as insulin, insulin-like growth factor I, and oxidative stress and
is thought to be an important mechanism that can influence intracellular ... Cited by 15 - Related articles - BL Direct - All 5 versions
[CITATION] Defective signaling through Akt-2 and-3 but not Akt-1 is reduced in insulin-resistant skeletal …
- ►shouxi.net HF Kramer, CA Witczak, EB Taylor, N Fujii, … - Journal of Biological Chemistry, 2006 - ASBMB Insulin and contraction are potent stimulators of GLUT4 translocation and
increase skeletal muscle glucose uptake. We recently identified the Rab
GTPase-activating protein (GAP) AS160 as a putative point of convergence ... Cited by 63 - Related articles - All 6 versions
