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Scholar Results 1 - 10 of about 101 related to Shinohara: Phosphatidylinositol 3-Kinase–Dependent Activation of Akt, an Essential Signal.... (0.09 sec) 

Phosphatidylinositol 3-Kinase–Dependent Activation of Akt, an Essential Signal for …

- diabetesjournals.org
T Shinohara, N Takahashi, T Ooie, M Hara, … - Diabetes, 2006 - Am Diabetes Assoc
We tested the hypothesis that phosphatidylinositol 3-kinase (PI
3-kinase)-dependent activation of Akt is essential for the expression of cardiac
heat-shock protein 72 (HSP72) and that this pathway is impaired in the ...
Cited by 20 - Related articles - BL Direct - All 4 versions

Phosphatidylinositol 3-KinaseeCDependent Activation of Akt, an Essential Signal for …


T Shinohara, N Takahashi, T Ooie, M Hara, … - 糖尿病学杂志, 2006 - journal.shouxi.net
We tested the hypothesis that phosphatidylinositol 3-kinase (PI
3-kinase)-dependent activation of Akt is essential for the expression of cardiac
heat-shock protein 72 (HSP72) and that this pathway is impaired in the ...
Related articles - Cached

Pioglitazone but not glibenclamide improves cardiac expression of heat shock protein 72 and …


Y Taniguchi, T Ooie, N Takahashi, T … - Diabetes, 2006 - Am Diabetes Assoc
We tested the hypothesis that pioglitazone could restore expression of heat
shock protein (HSP)72 in insulin-resistant rat heart. At 12 weeks of age, male
Otsuka Long-Evans Tokushima Fatty (OLETF) rats and control (LETO) rats were ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Mitochondria are targets for geranylgeranylacetone-induced cardioprotection against …

- physiology.org
T Shinohara, N Takahashi, H Kohno, K … - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc
It has been shown that orally administered geranylgeranylacetone (GGA), an
anti-ulcer drug, induces expression of heat shock protein 72 (HSP72) and
provides protection against ischemia-reperfusion in rat hearts. The ...
Cited by 13 - Related articles - BL Direct - All 3 versions

Role of protein kinase C in geranylgeranylacetone-induced expression of heat-shock protein …


K Yamanaka, N Takahashi, T Ooie, K Kaneda, … - Journal of molecular and cellular cardiology, 2003 - Elsevier
We recently demonstrated that oral administration of geranylgeranylacetone
(GGA), an antiulcer agent, induces heat-shock protein 72 (HSP72) in the rat
heart and renders cardioprotection against ischemia/reperfusion injury. ...
Cited by 41 - Related articles - All 8 versions

Estrogen inhibits hyperthermia-induced expression of heat-shock protein 72 and …


T Shinohara, N Takahashi, T Ooie, M … - Journal of molecular and cellular cardiology, 2004 - Elsevier
There is still controversy as to whether estrogen inhibits or enhances
heat-shock protein (HSP72) expression in the heart. To evaluate the gender
difference, whole-body hyperthermia (HT, 43 °C for 20 min) or normothermia ...
Cited by 25 - Related articles - All 6 versions

Loss of defense against stress: diabetes and heat shock proteins

- hspsanddiabetes.com [PDF] 
PL Hooper, JJ Hooper - Diabetes Technology & Therapeutics, 2005 - liebertonline.com
W E PROPOSE THAT DIABETES produces a vul- nerable condition with impaired de-
fenses against stress, resulting in widespread unprotected organ systems. More
specifi- cally, the ultimate natural history of diabetes and its ...
Cited by 16 - Related articles - All 4 versions

[CITATION] BGP-15, a new type of insulin sensitizer


A Kolonics, B Peitl, A Bajza, L Jaszlits, L … - Diabetes, 2006
Cited by 4 - Related articles

Comparison of the extrapancreatic action of BRX-220 and pioglitazone in the high-fat diet- …


E ŠEBÖKOVÁ, M KÜRTHY, T Mogyorosi, K … - Annals of the New York Academy of Sciences, 2002 - interscience.wiley.com
Abstract: A new Biorex molecule, BRX-220, has been shown to be effective in
animal models of diabetic neuro- and retinopathy. Recent in vitro studies showed
that it might also have an insulin-sensitizing action. Therefore, the ...
Cited by 4 - Related articles - BL Direct - All 5 versions

Phosphorylated heat shock protein 27 is involved in enhanced heart tolerance to ischemia in …


H Chen, XJ Wu, XY Lu, L Zhu, LP Wang, HT … - Acta Pharmacol Sin, 2005 - chinaphar.com
It is well known that cardiovascular disease is the major cause of morbidity and
mortality in diabetic patients. However, there exists considerable debate over
the causal relationship between diabetes per se and cardiovascular disease ...
Cited by 16 - Related articles - Cached - All 8 versions


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