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Scholar Results 1 - 10 of about 101 related to Ihm: Effect of donor age on function of isolated human islets. (0.11 sec) 

Effect of donor age on function of isolated human islets

- diabetesjournals.org
SH Ihm, I Matsumoto, T Sawada, M Nakano, HJ Zhang, … - Diabetes, 2006 - Am Diabetes Assoc
This study intended to evaluate the impact of donor age on the function of isolated islets. Analysis
of human islets from cadaveric donors (age 16–70 years) was performed using glucose-stimulated
insulin release (GSIR) (n = 93), islet ATP content (n = 27), diabetic nude mouse bioassay ...
Cited by 22 - Related articles - BL Direct - All 6 versions

Suitability of human juvenile pancreatic islets for clinical use


AN Balamurugan, Y Chang, S Bertera, A Sands, V … - Diabetologia, 2006 - Springer
Page 1. ARTICLE Suitability of human juvenile pancreatic islets for clinical use AN
Balamurugan & Y. Chang & S. Bertera & A. Sands & V. Shankar & M. Trucco & R. Bottino
Received: 6 March 2006 /Accepted: 20 April 2006 / Published ...
Cited by 10 - Related articles - BL Direct - All 3 versions

Kyoto islet isolation method: the optimized one for non-heart-beating donors with …


T Okitsu, S Matsumoto, Y Iwanaga, H Noguchi, H … - Transplantation …, 2005 - Elsevier
The availability of pancreata for clinical cadaveric islet transplantation is restricted to
non-heart-beating donors (NHBDs) in Japan. This forced us to modify the current standard islet
isolation protocol that was made up for brain-dead donors and make it suitable for ...
Cited by 6 - Related articles - All 10 versions

Improvement of pancreatic islet cell isolation for transplantation


S Matsumoto, H Noguchi, B Naziruddin, N … - Proceedings (Baylor …, 2007 - pubmedcentral.nih.gov
Pancreatic islet transplantation is a promising treatment for diabetes but still faces several
challenges. Poor islet isolation efficiency and poor long-term insulin independence are currently
two major issues, although donor shortage and the need for immunosuppressants also ...
Cited by 3 - Related articles - All 10 versions

Pancreatic islet transplantation for treating diabetes

- psu.edu [PDF] 
S Matsumoto, H Noguchi, Y Yonekawa, T … - Expert Opin. Biol. …, 2006 - informahealthcare.com
Pancreatic islet transplantation is one of the options for treating diabetes and has been shown
to improve the quality of life of severe diabetic patients. Since the Edmonton protocol was
announced, islet transplantation have advanced considerably, including islet after kidney ...
Cited by 12 - Related articles - BL Direct - All 8 versions

Successful islet transplantation from nonheartbeating donor pancreata using …


S Matsumoto, T Okitsu, Y Iwanaga, H Noguchi, H … - Transplantation, 2006 - journals.lww.com
Islet transplantation has proven to be highly effective for reversing the diabetic state of patients
with type 1 diabetes (1, 2). Because the number of cadaveric donors is inadequate to treat the
number of qualifying type 1 diabetic patients, the utilization of marginal donor pancreata ...
Cited by 39 - Related articles - BL Direct - All 7 versions

Factors influencing the collagenase digestion phase of human islet isolation


T Kin, PRV Johnson, AMJ Shapiro, JRT Lakey - Transplantation, 2007 - journals.lww.com
Substantial advances in human islet isolation technology have occurred during the past
decade. However, it is still difficult to recover the entire quantity of islets contained in a
pancreas. A major obstacle to successful human islet isolation has been the variability of ...
Cited by 9 - Related articles - BL Direct - All 4 versions

NON-HEART-BEATING ORGAN DONORS: A Potential Source of Islets for …


HA Clayton, SM Swift, JM Turner, RFL James, PRF … - Transplantation, 2000 - journals.lww.com
Skip Navigation Links Home > May 27, 2000 - Volume 69 - Issue 10 > NON-HEART-BEATING
ORGAN DONORS: A Potential Source of Islets... ... 2 Address correspondence to: Dr. Heather
Clayton, Department of General Surgery, Ward 16, Leicester General Hospital, Leicester ...
Cited by 23 - Related articles - BL Direct - All 5 versions

Enhancing the success of human islet isolation through optimization and …


T Kin, X Zhai, TB Murdoch, A Salam, AMJ … - American Journal of …, 2007 - interscience.wiley.com
A major obstacle to successful human islet isolation has been the variability of the enzymatic
digestion phase. The aim of this study was to define optimal enzyme activity ranges normalized
by the pancreas weight and to identify valid parameters for the optimal selection of ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Analysis of donor-and isolation-related variables from non-heart-beating donors ( …


X Liu, S Matsumoto, T Okitsu, Y Iwanaga, H … - Cell …, 2008 - ingentaconnect.com
Recently, we demonstrated that islet transplantation from non-heart-beating donors (NHBDs)
using the Kyoto islet isolation method (KIIM) successfully reversed patients' diabetes state. In
this study, we evaluated the effects of donor- and isolation-related variables on islet ...
Cited by 1 - Related articles - All 4 versions


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