- ►diabetesjournals.org SH Ihm, I Matsumoto, T Sawada, M Nakano, HJ Zhang, … - Diabetes, 2006 - Am Diabetes Assoc This study intended to evaluate the impact of donor age on the function of isolated islets. Analysis
of human islets from cadaveric donors (age 16–70 years) was performed using glucose-stimulated
insulin release (GSIR) (n = 93), islet ATP content (n = 27), diabetic nude mouse bioassay ... Cited by 22 - Related articles - BL Direct - All 6 versions
AN Balamurugan, Y Chang, S Bertera, A Sands, V … - Diabetologia, 2006 - Springer Page 1. ARTICLE Suitability of human juvenile pancreatic islets for clinical use AN
Balamurugan & Y. Chang & S. Bertera & A. Sands & V. Shankar & M. Trucco & R. Bottino
Received: 6 March 2006 /Accepted: 20 April 2006 / Published ... Cited by 10 - Related articles - BL Direct - All 3 versions
T Okitsu, S Matsumoto, Y Iwanaga, H Noguchi, H … - Transplantation …, 2005 - Elsevier The availability of pancreata for clinical cadaveric islet transplantation is restricted to
non-heart-beating donors (NHBDs) in Japan. This forced us to modify the current standard islet
isolation protocol that was made up for brain-dead donors and make it suitable for ... Cited by 6 - Related articles - All 10 versions
S Matsumoto, H Noguchi, B Naziruddin, N … - Proceedings (Baylor …, 2007 - pubmedcentral.nih.gov Pancreatic islet transplantation is a promising treatment for diabetes but still faces several
challenges. Poor islet isolation efficiency and poor long-term insulin independence are currently
two major issues, although donor shortage and the need for immunosuppressants also ... Cited by 3 - Related articles - All 10 versions
- ►psu.edu [PDF] S Matsumoto, H Noguchi, Y Yonekawa, T … - Expert Opin. Biol. …, 2006 - informahealthcare.com Pancreatic islet transplantation is one of the options for treating diabetes and has been shown
to improve the quality of life of severe diabetic patients. Since the Edmonton protocol was
announced, islet transplantation have advanced considerably, including islet after kidney ... Cited by 12 - Related articles - BL Direct - All 8 versions
S Matsumoto, T Okitsu, Y Iwanaga, H Noguchi, H … - Transplantation, 2006 - journals.lww.com Islet transplantation has proven to be highly effective for reversing the diabetic state of patients
with type 1 diabetes (1, 2). Because the number of cadaveric donors is inadequate to treat the
number of qualifying type 1 diabetic patients, the utilization of marginal donor pancreata ... Cited by 39 - Related articles - BL Direct - All 7 versions
T Kin, PRV Johnson, AMJ Shapiro, JRT Lakey - Transplantation, 2007 - journals.lww.com Substantial advances in human islet isolation technology have occurred during the past
decade. However, it is still difficult to recover the entire quantity of islets contained in a
pancreas. A major obstacle to successful human islet isolation has been the variability of ... Cited by 9 - Related articles - BL Direct - All 4 versions
HA Clayton, SM Swift, JM Turner, RFL James, PRF … - Transplantation, 2000 - journals.lww.com Skip Navigation Links Home > May 27, 2000 - Volume 69 - Issue 10 > NON-HEART-BEATING
ORGAN DONORS: A Potential Source of Islets... ... 2 Address correspondence to: Dr. Heather
Clayton, Department of General Surgery, Ward 16, Leicester General Hospital, Leicester ... Cited by 23 - Related articles - BL Direct - All 5 versions
T Kin, X Zhai, TB Murdoch, A Salam, AMJ … - American Journal of …, 2007 - interscience.wiley.com A major obstacle to successful human islet isolation has been the variability of the enzymatic
digestion phase. The aim of this study was to define optimal enzyme activity ranges normalized
by the pancreas weight and to identify valid parameters for the optimal selection of ... Cited by 12 - Related articles - BL Direct - All 4 versions
X Liu, S Matsumoto, T Okitsu, Y Iwanaga, H … - Cell …, 2008 - ingentaconnect.com Recently, we demonstrated that islet transplantation from non-heart-beating donors (NHBDs)
using the Kyoto islet isolation method (KIIM) successfully reversed patients' diabetes state. In
this study, we evaluated the effects of donor- and isolation-related variables on islet ... Cited by 1 - Related articles - All 4 versions