- ►diabetesjournals.org F Ranta, D Avram, S Berchtold, M Düfer, G … - Diabetes, 2006 - Am Diabetes Assoc Glucocorticoid excess induces hyperglycemia, which may result in diabetes. The
present experiments explored whether glucocorticoids trigger apoptosis in
insulin-secreting cells. Treatment of mouse β-cells or INS-1 cells with ... Cited by 31 - Related articles - BL Direct - All 6 versions
- ►shouxi.net S Ullrich, S Berchtold, F Ranta, G Seebohm, … - Diabetes, 2005 - Am Diabetes Assoc Glucocorticoid excess predisposes to the development of diabetes, at least in
part through impairment of insulin secretion. The underlying mechanism has
remained elusive. We show here that dexamethasone upregulates transcription ... Cited by 50 - Related articles - All 5 versions
- ►highwire.org WY Almawi, OK Melemedjian, MMA Jaoude - Journal of leukocyte biology, 2004 - jleuk.highwire.org As immunosuppressive agents, glucocorticoids (GCs) act by inhibiting the
expression of cytokines and adhesion molecules at the transcriptional and
post-transcriptional levels. In addition, GCs exerted their effects by ... Cited by 17 - Related articles - BL Direct - All 7 versions
D Hamamdzic, E Duzic, JD Sherlock, SM … - American Journal of Physiology- Endocrinology And …, 1995 - Am Physiological Soc Activation of az-adrenergic receptors &-AR> in pancreatic P-cells inhibits
insulin secretion in response to various stimuli, and acute or long-term
regulation of (x2-AR receptor-mediated effects may influence the tissue ... Cited by 21 - Related articles - BL Direct - All 3 versions
KH Yew, KL Prasadan, BL Preuett, MJ Hembree … - Diabetes, 2004 - Am Diabetes Assoc The differentiation of pancreatic exocrine AR42J cells into insulin-expressing
endocrine cells has served as an important model for both endogenous in vivo
β-cell differentiation as well as potential application to β-cell ... Cited by 11 - Related articles - BL Direct - All 4 versions
- ►endojournals.org AJ Weinhaus, NV Bhagroo, TC Brelje, RL … - Endocrinology, 2000 - Endocrine Soc Islets undergo a number of up-regulatory changes to meet the increased demand
for insulin during pregnancy, including increased insulin secretion and ß-cell
proliferation. It has been shown that elevated lactogenic hormone is ... Cited by 26 - Related articles - BL Direct - All 3 versions
- ►shouxi.net Y Fujinaka, K Takane, H Yamashita, RC … - Journal of Biological Chemistry, 2007 - ASBMB One of the goals in the treatment for diabetes is to enhance pancreatic beta
cell function, proliferation, and survival. This study explores the role of
lactogenic hormones, prolactin (PRL) and placental lactogen (PL), in beta ... Cited by 14 - Related articles - All 4 versions
M Ferdaoussi, S Abdelli, JY Yang, M Cornu, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Ex-4 inhibited induction of the JNK pathway elicited by IL-1β. This
effect was mimicked with the use of cAMP-raising agents isobutylmethylxanthine
and forskolin and required activation of the protein kinase A. Inhibition ... Cited by 14 - Related articles - BL Direct - All 3 versions
IK Jeong, SH Oh, BJ Kim, JH Chung, YK Min, … - Diabetes research and clinical practice, 2001 - Elsevier Complex results concerning the effect of glucocorticoids on insulin secretion
have been reported. The aim of this study is to clarify the direct effects of
glucocorticoids on pancreatic islets and to determine whether the effect of ... Cited by 19 - Related articles - All 5 versions
- ►endocrinology-journals.org MJ Kim, JH Kang, YG Park, GR Ryu, SH Ko, … - Journal of Endocrinology, 2006 - Soc Endocrinology Glucagon-like peptide-1 (GLP-1) and its analog exendin-4 (EX) have been
considered as a growth factor implicated in pancreatic islet mass increase and
ß-cell proliferation. This study aimed to investigate the effect of EX on ... Cited by 19 - Related articles - BL Direct - All 6 versions
