- ►shouxi.net DR Gable, JW Stephens, JA Cooper, GJ … - Diabetes, 2006 - Am Diabetes Assoc The impact of the UCP2 −866G>A and UCP3 −55C>T variants on prospective risk
of type 2 diabetes was examined over 15 years in 2,936 healthy middle-aged men
(mean age 56 years). Conversion to diabetes (n = 169) was associated with ... Cited by 39 - Related articles - BL Direct - All 6 versions
A Meirhaeghe, P Amouyel, N Helbecque, D … - Diabetologia, 2000 - Springer Aims/hypothesis. The UCP2-UCP3 gene region has been previously associated with
obesity and diabetes. In a large representative cohort of Northern France
(MONICA project), we studied the effect of a recent- ly reported C/T ... Cited by 40 - Related articles - BL Direct - All 3 versions
- ►physiology.org YJ Liu, PY Liu, J Long, Y Lu, L Elze, RR … - Physiological Genomics, 2005 - Am Physiological Soc Uncoupling protein 3 (UCP3) uncouples ATP production from mitochondrial
respiration, thereby dissipating energy as heat and affecting the efficiency of
energy metabolism. Genetic variations in the UCP3 gene have been conceived ... Cited by 25 - Related articles - BL Direct - All 4 versions
SM Herrmann, JG Wang, JA Staessen, E … - Journal of Molecular Medicine, 2003 - Springer Abstract Body weight regulation is a complex pheno- type also depending on the
action of uncoupling proteins (UCPs) that mediate the “uncoupling” of
respiration leading to the dissipation of energy as heat. This study ... Cited by 25 - Related articles - BL Direct - All 3 versions
- ►physiology.org H Wang, WS Chu, T Lu, SJ Hasstedt, PA Kern, … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc The onset of type 2 diabetes (T2DM) is preceded by obesity, insulin resistance,
and impaired -cell function. Uncoupling protein-2 (UCP2) is a widely expressed
inner mitochondrial membrane protein. Common polymorphisms of the UCP2 gene ... Cited by 63 - Related articles - BL Direct - All 5 versions
DJ Halsall, J Luan, P Saker, S Huxtable, IS … - Int J Obes Relat Metab Disord, 2001 - grande.nal.usda.gov Record Detail. Return to previous page, Save: Title: Uncoupling protein 3 genetic
variants in human obesity: the c-55t promoter polymorphism ... Cited by 44 - Related articles - Cached - BL Direct - All 4 versions
P Kovacs, L Ma, RL Hanson, P Franks, M … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Uncoupling protein-2 (UCP2) is thought to play a role
in insulin secretion and the de- velopment of obesity. In this study, we
investigated the effects of genetic variation in UCP2 on type 2 diabetes ... Cited by 28 - Related articles - BL Direct - All 4 versions
F Krempler, H Esterbauer, R Weitgasser, C … - Diabetes, 2002 - Am Diabetes Assoc Obesity is frequently associated with type 2 diabetes. We previously observed an
association of a functional G/A polymorphism in the uncoupling protein 2 (UCP2)
promoter with obesity. The wild-type G allele was associated with reduced ... Cited by 95 - Related articles - BL Direct - All 4 versions
M Sasahara, M Nishi, H Kawashima, K Ueda, … - Diabetes, 2004 - Am Diabetes Assoc Common uncoupling protein 2 (UCP2) promoter polymorphism −866G/A is reported
to be associated with its expression in adipose tissue and the risk of obesity
in Caucasians. On the other hand, several studies suggested that UCP2 ... Cited by 60 - Related articles - BL Direct - All 4 versions
MD'Adamo, L Perego, M Cardellini, MA Marini, S … - Diabetes, 2004 - Am Diabetes Assoc Uncoupling protein (UCP)-2 is a member of the mitochondrial inner membrane
carriers that uncouple pro-ton entry in the mitochondrial matrix from ATP
synthesis. The −866G/A polymorphism in the UCP2 gene, which enhances its ... Cited by 64 - Related articles - BL Direct - All 5 versions
