A Mas, J Montané, XM Anguela, S Muñoz, AM Douar, E … - Diabetes, 2006 - Am Diabetes Assoc Type 1 diabetic patients develop severe secondary complications because insulin treatment
does not guarantee normoglycemia. Thus, efficient regulation of glucose homeostasis is a major
challenge in diabetes therapy. Skeletal muscle is the most important tissue for glucose ... Cited by 10 - Related articles - BL Direct - All 6 versions
PJ Otaegui, M Ontiveros, T Ferre, E Riu, R … - Human gene …, 2002 - liebertonline.com Type 1 diabetic patients depend on insulin replacement therapy. However, chronic hyperglycemia
due to fail- ure to maintain proper glycemic control leads to microvascular, macrovascular, and
neurological complica- tions. Increased glucose disposal by tissues engineered to ... Cited by 5 - Related articles - BL Direct - All 5 versions
- ►fasebj.org [PDF] GJ Liu, AM Simpson, MA Swan, C Tao, BE Tuch, RM … - The FASEB Journal, 2003 - FASEB Page 1. The FASEB Journal express article 10.1096/fj.02-0051fje. Published online July 18, 2003.
ATP-sensitive potassium channels induced in liver cells after transfection with insulin cDNA and
the GLUT2 transporter regulate glucose-stimulated insulin secretion ... Cited by 6 - Related articles - BL Direct - All 6 versions
PY Hsu, Y Yang - JOURNAL OF GENE MEDICINE, 2005 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 6 - Related articles - BL Direct - All 2 versions
YD Kim, KG Park, R Morishita, Y Kaneda, SY Kim, DK … - Gene therapy, 2006 - cms1.daegu.ac.kr Insulin gene therapy in clinical medicine is currently hampered by the inability to regulate insulin
secretion in a physiological manner, the inefficiency with which the gene is delivered, and the
short duration of gene expression. To address these issues, we injected the liver of ... Cited by 6 - Related articles - View as HTML - BL Direct - All 6 versions
E Riu, A Mas, T Ferre, A Pujol, L Gros, P Otaegui, L … - Diabetes, 2002 - Am Diabetes Assoc Insulin replacement therapy in type 1 diabetes is imperfect because proper glycemic control
is not always achieved. Most patients develop microvascular, macrovascular, and neurological
complications, which increase with the degree of hyperglycemia. Engineered muscle ... Cited by 16 - Related articles - BL Direct - All 5 versions
PJ Otaegui, T Ferre, A Pujol, E Riu, R Jimenez, F … - Human gene …, 2000 - liebertonline.com Chronic hyperglycemia is responsible for diabetes-specific microvascular and macrovascular
complications. To reduce hyperglycemia, key tissues may be engineered to take up glucose.
To determine whether an in- crease in skeletal muscle glucose phosphorylation leads to ... Cited by 17 - Related articles - BL Direct - All 4 versions
- ►endocrinology-journals.org [PDF] CW Hay, K Docherty - Journal of molecular endocrinology, 2003 - Soc Endocrinology Cell engineering or gene therapy may represent an alternative to current methods of treating
diabetes mellitus. Cells could be engineered to secrete insulin ex vivo for transplantation or the
insulin gene could be administered directly by injection into muscle. A problem has been ... Cited by 8 - Related articles - BL Direct - All 4 versions
JDMABMBC BSc, JLMMDMS FRCPC - CANADIAN JOURNAL OF …, 2007 - diabetes.ca Putative therapeutic interventions with hypothetical clinical benefit in overt type 1 diabetes, or
in the pre-clinical condi- tion with evidence of the active autoimmune process, or in people at
risk for the disease by virtue of family history with or without genotypic evidence of ... Related articles - View as HTML - BL Direct - All 3 versions
JM MOGAS - tdx.cbuc.es Page 1. Departament de Bioquímica i Biologia Molecular de la FACULTAT DE VETERINÀRIA
CENTRE DE BIOTECNOLOGIA ANIMAL I TERÀPIA GÈNICA (CBATEG) CONTRARESTACIÓ
DE LA DIABETIS MELLITUS MITJANÇANT LA GENERACIÓ D'UN SENSOR DE LA ... Related articles - All 8 versions
