- ►diabetesjournals.org F Homo-Delarche, S Calderari, JC Irminger, … - Diabetes, 2006 - Am Diabetes Assoc The molecular pathways leading to islet fibrosis in diabetes are unknown.
Therefore, we studied gene expression in islets of 4-month-old Goto-Kakizaki
(GK) and Wistar control rats. Of 71 genes found to be overexpressed in GK ... Cited by 44 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org JA Ehses, A Perren, E Eppler, P Ribaux, JA … - Diabetes, 2007 - Am Diabetes Assoc Activation of the innate immune system in obesity is a risk factor for the
development of type 2 diabetes. The aim of the current study was to investigate
the notion that increased numbers of macrophages exist in the islets of ... Cited by 46 - Related articles - BL Direct - All 11 versions
- ►shouxi.net X Li, L Zhang, S Meshinchi, C Dias-Leme, D … - Diabetes, 2006 - Am Diabetes Assoc Gene expression profiling of islets from pre-diabetic male Zucker diabetic fatty
(ZDF) rats showed increased expression of hypoxia-related genes, prompting
investigation of the vascular integrity of the islets. The islet ... Cited by 28 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org YP Zhou, A Madjidi, ME Wilson, DA … - Diabetes, 2005 - Am Diabetes Assoc To assess the molecular changes associated with pancreatic β-cell dysfunction
occurring during the onset of type 2 diabetes, we profiled pancreatic islet
mRNAs from diabetic male and high-fat–fed female Zucker diabetic fatty ... Cited by 19 - Related articles - BL Direct - All 5 versions
B Portha, MH Giroix, P Serradas, MN … - Diabetes, 2001 - Am Diabetes Assoc The GK rat model of type 2 diabetes is especially convenient to dissect the
pathogenic mechanism necessary for the emergence of overt diabetes because all
adult rats obtained in our department (GK/Par colony) to date have stable ... Cited by 34 - Related articles - BL Direct - All 5 versions
HL Zhao, FMM Lai, PCY Tong, DR Zhong, D … - Diabetes, 2003 - Am Diabetes Assoc Islet amyloid has been suggested to be an important link between insulin
resistance and β-cell dysfunction in type 2 diabetes. To investigate the
prevalence and clinicopathological characteristics of islet amyloid, we ... Cited by 32 - Related articles - BL Direct - All 5 versions
PO Carlsson, L Jansson, CG Ostenson, O … - Diabetes, 1997 - Am Diabetes Assoc This study was performed to measure pancreatic islet capillary pressure under
basal conditions and after an acute glucose stimulation of insulin release in
normal rats. In addition, the islet capillary pressure was estimated in GK ... Cited by 56 - Related articles - BL Direct - All 5 versions
- ►physiology.org AM Svensson, CG Ostenson, L Jansson - American Journal of Physiology- Endocrinology And …, 2000 - Am Physiological Soc The present study aimed to compare longitudinal variations in islet blood
perfusion in rats with different degrees of impairment of glucose metabolism.
For this purpose, mildly diabetic Goto-Kakizaki (GK) rats, glucose ... Cited by 25 - Related articles - BL Direct - All 3 versions
F Miralles, B Portha - Diabetes, 2001 - Am Diabetes Assoc The Goto-Kakisaki (GK) rat is a genetic model of type 2 diabetes obtained by
selective inbreeding of mildly glucose-intolerant Wistar rats. Previous studies
have shown that at birth, the -cell mass of the GK rat is severely reduced ... Cited by 28 - Related articles - BL Direct - All 4 versions
SH Ko, HS Kwon, SR Kim, SD Moon, YB Ahn, … - Biochemical and biophysical research communications, 2004 - Elsevier We evaluated whether ramipril, one of long-acting ACEIs, has a direct effect on
pancreas islets in animal model of type 2 diabetes. OLETF rats were treated with
ramipril for 24 weeks. We assessed the body weight, glucose tolerance, and ... Cited by 40 - Related articles - All 8 versions
