S Menini, L Amadio, G Oddi, C Ricci, C Pesce, … - Diabetes, 2006 - Am Diabetes Assoc Hyperglycemia plays a central role in diabetic nephropathy, as shown by its
prevention or retardation by strict metabolic control (1,2). The injurious
effect of hyperglycemia has been attributed to various biochemical ... Cited by 47 - Related articles - BL Direct - All 6 versions
- ►endojournals.org E Pagnin, G Fadini, R de Toni, A Tiengo, L … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc Oxidative stress plays a role in cardiovascular dysfunction. This is of interest
in diabetes, a clinical condition characterized by oxidative stress and
increased prevalence of cardiovascular disease. The role of p66 shc in ... Cited by 41 - Related articles - All 5 versions
GG Camici, M Schiavoni, P Francia, M … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences Increased production of reactive oxygen species (ROS) and loss of endothelial NO
bioavailability are key features of vascular disease in diabetes mellitus. The
p66 Shc adaptor protein controls cellular responses to oxidative stress. ... Cited by 44 - Related articles - BL Direct - All 10 versions
C Napoli, I Martin-Padura, F de Nigris, M … - Proceedings of the National Academy of Sciences of …, 2003 - National Acad Sciences Several experimental and clinical studies have shown that oxidized low-density
lipoprotein and oxidation-sensitive mechanisms are central in the pathogenesis
of vascular dysfunction and atherogenesis. Here, we have used p66 ... Cited by 138 - Related articles - BL Direct - All 9 versions
- ►jbc.org S Nemoto, CA Combs, S French, BH Ahn, MM … - Journal of Biological Chemistry, 2006 - ASBMB Previous studies have determined that mice with a homozygous deletion in the
adapter protein p66 shc have an extended life span and that cells derived from
these mice exhibit lower levels of reactive oxygen species. Here we ... Cited by 47 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org G Zaccagnini, F Martelli, P Fasanaro, A … - Circulation, 2004 - Am Heart Assoc Methods and Results— Unilateral hindlimb ischemia was induced by femoral
artery dissection, and ischemia/reperfusion was induced with an elastic
tourniquet. Both procedures caused similar changes in blood perfusion in ... Cited by 53 - Related articles - All 9 versions
- ►nih.gov S Pacini, M Pellegrini, E Migliaccio, L Patrussi … - Molecular and Cellular Biology, 2004 - Am Soc Microbiol Of the three Shc isoforms, p66Shc is responsible for fine-tuning p52/p46Shc
signaling to Ras and has been implicated in apoptotic responses to oxidative
stress. Here we show that human peripheral blood lymphocytes and mouse ... Cited by 56 - Related articles - BL Direct - All 6 versions
P Pinton, A Rimessi, S Marchi, F Orsini, E … - Science, 2007 - sciencemag.org A list of selected additional articles on the Science Web sites ... 36
article(s) on the ISI Web of Science. cited by This article has been ... :
subject collections This article appears in the following Cited by 82 - Related articles - BL Direct - All 7 versions
- ►jbc.org F Orsini, E Migliaccio, M Moroni, C Contursi, … - Journal of Biological Chemistry, 2004 - ASBMB P66Shc regulates life span in mammals and is a critical component of the
apoptotic response to oxidative stress. It functions as a downstream target of
the tumor suppressor p53 and is indispensable for the ability of oxidative ... Cited by 92 - Related articles - BL Direct - All 4 versions
