- ►diabetesjournals.org RJ McCrimmon, X Fan, H Cheng, E McNay, O … - Diabetes, 2006 - Am Diabetes Assoc Defective counterregulatory responses (CRRs) to hypoglycemia are associated with
a marked increase in the risk of severe hypoglycemia. The mechanisms leading to
the development of defective CRRs remain largely unknown, although they are ... Cited by 28 - Related articles - BL Direct - All 5 versions
- ►nih.gov RJ McCrimmon, Z Song, H Cheng, EC McNay, … - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig Recurrent episodes of hypoglycemia impair sympathoadrenal counterregulatory
responses (CRRs) to a subsequent episode of hypoglycemia. For individuals with
type 1 diabetes, this markedly increases (by 25-fold) the risk of severe ... Cited by 28 - Related articles - BL Direct - All 11 versions
RJ McCrimmon, X Fan, Y Ding, W Zhu, RJ … - Diabetes, 2004 - Am Diabetes Assoc The mechanisms by which specialized glucose-sensing neurons within the
hypothalamus are able to detect a falling blood glucose remain largely unknown
but may be linked to some gauge of neuronal energy status. We sought to ... Cited by 58 - Related articles - BL Direct - All 4 versions
- ►endojournals.org T Alquier, J Kawashima, Y Tsuji, BB Kahn - Endocrinology, 2007 - Endocrine Soc Antecedent hypoglycemia blunts counterregulatory responses that normally restore
glycemia, a phenomenon known as hypoglycemia-associated autonomic failure
(HAAF). The mechanisms leading to impaired counterregulatory responses are ... Cited by 8 - Related articles - BL Direct - All 3 versions
SM Han, C Namkoong, PG Jang, IS Park, SW … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 2170–2178 DOI 10.1007/s00125-005-1913-1 ARTICLE
S.-M. Han . C. Namkoong . PG Jang . IS Park . SW Hong . H. Katakami . ... Cited by 30 - Related articles - BL Direct - All 3 versions
- ►physiology.org DD Canabal, Z Song, JG Potian, A Beuve, JJ … - … Journal of Physiology- Regulatory, Integrative and …, 2007 - Am Physiological Soc Glucose-sensing neurons in the ventromedial hypothalamus (VMH) are involved in
the regulation of glucose homeostasis. Glucose-sensing neurons alter their
action potential frequency in response to physiological changes in ... Cited by 27 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org RJ McCrimmon, ML Evans, X Fan, EC McNay, … - Diabetes, 2005 - Am Diabetes Assoc The mechanism(s) by which glucosensing neurons detect fluctuations in glucose
remains largely unknown. In the pancreatic β-cell, ATP-sensitive K + channels
(K ATP channels) play a key role in glucosensing by providing a link ... Cited by 24 - Related articles - BL Direct - All 6 versions
- ►shouxi.net O Chan, W Zhu, Y Ding, RJ McCrimmon, RS … - Diabetes, 2006 - Am Diabetes Assoc Hypoglycemia provokes a multifaceted counterregulatory response involving the
sympathoadrenal system, stimulation of glucagon secretion, and the
hypothalamo-pituitary-adrenal axis that is commonly impaired in diabetes. ... Cited by 11 - Related articles - BL Direct - All 5 versions
- ►physiology.org Z Song, VH Routh - … Journal of Physiology- Regulatory, Integrative and …, 2006 - Am Physiological Soc Recurrent hypoglycemia blunts the brain's ability to sense and respond to
subsequent hypoglycemic episodes. Glucose-sensing neurons in the ventromedial
hypothalamus nucleus (VMN) are well situated to play a role in hypoglycemia ... Cited by 22 - Related articles - All 5 versions
PD Mountjoy, SJ Bailey, GA Rutter - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Changes in the activity of glucose-excited and
glucose-inhibited neurons within the basomedial hypothalamus are key to the
central regulation of satiety. However, the molecular mechanisms through ... Cited by 25 - Related articles - BL Direct - All 6 versions
