- ►diabetesjournals.org R Ouedraogo, X Wu, SQ Xu, L Fuchsel, H Motoshima, … - Diabetes, 2006 - Am Diabetes Assoc Adiponectin is an abundant adipocyte-derived plasma protein with antiatherosclerotic
effects. Vascular signal transduction by adiponectin is poorly understood and may involve
5′-AMP–activated protein kinase (AMPK), cAMP signaling, and other pathways. ... Cited by 56 - Related articles - BL Direct - All 6 versions
R Ouedraogo, X Wu, SQ Xu, L Fuchsel, H Motoshima, … - DIABETES, 2006 - Am Diabetes Assoc Page 1. Original Article Adiponectin Suppression of High-Glucose–Induced Reactive
Oxygen Species in Vascular Endothelial Cells Evidence for Involvement of a cAMP
Signaling Pathway Raogo Ouedraogo, 1 Xiangdong Wu ... Related articles
BJ Goldstein, R Scalia - Current Diabetes Reports, 2007 - Springer Adipokines, in particular adiponectin, have been high- lighted in the pathogenesis of
obesity-related illnesses, including type 2 diabetes, because of their role in the regulation of
insulin sensitivity as well as vascular endo- thelial function. Since cardiovascular disease ... Cited by 18 - Related articles - BL Direct - All 2 versions
W Xi, H Satoh, H Kase, K Suzuki, Y Hattori - Biochemical and Biophysical …, 2005 - Elsevier The present study examined potential interactions between endothelial NO synthase
(eNOS), heat shock protein (HSP)90, and Akt in vascular endothelial cells stimulated with globular
adiponectin to produce nitric oxide (NO). Globular adiponectin-induced eNOS ... Cited by 37 - Related articles - All 4 versions
- ►nih.gov R Ouedraogo, Y Gong, B Berzins, X Wu, K … - Journal of Clinical …, 2007 - Am Soc Clin Investig This study reports on what we believe are novel mechanism(s) of the vascular protective action
of adiponectin. We used intravital microscopy to measure leukocyte-endothelium interactions
in adiponectin-deficient (Ad –/– ) mice and found that adiponectin deficiency was ... Cited by 40 - Related articles - BL Direct - All 11 versions
KSL Lam, A Xu - Current Diabetes Reports, 2005 - Springer Introduction Obesity, especially central obesity, has been shown to predict cardiovascular morbidity
and mortality in long-term epide- miologic studies [1,2]. Although this may be attributed to its
association with insulin resistance and other related cardio- vascular risk factors, such as ... Cited by 54 - Related articles - BL Direct - All 2 versions
LY Lin, CY Lin, TC Su, CS Liau - FEBS letters, 2004 - Elsevier Adiponectin can protect vessels from injury by promoting the activity of endothelial nitric oxide
synthase (eNOS) with increased nitric oxide production. Recently, it was demonstrated that eNOS
activity is highly regulated by heat shock protein 90 (HSP90). We tested the hypothesis ... Cited by 40 - Related articles - All 8 versions
- ►ahajournals.org L Tao, E Gao, X Jiao, Y Yuan, S Li, TA Christopher, BL … - Circulation, 2007 - Am Heart Assoc Methods and Results— Adiponectin –/– or wild-type mice were subjected to 30 minutes of myocardial
ischemia followed by 3 hours or 24 hours (infarct size and cardiac function) of reperfusion. Myocardial
infarct size and apoptosis, production of peroxynitrite, nitric oxide (NO) and superoxide, ... Cited by 67 - Related articles - All 7 versions
- ►endojournals.org BJ Goldstein, R Scalia - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Cardiovascular disease accounts for an overwhelming proportion of the morbidity and mortality
suffered by patients with obesity and type 2 diabetes mellitus, and recent work has elucidated
several potential mechanisms by which increased adiposity enhances cardiovascular ... Cited by 329 - Related articles - BL Direct - All 6 versions
- ►upenn.edu [PDF] H Motoshima, X Wu, K Mahadev, BJ Goldstein - Biochemical and Biophysical …, 2004 - Elsevier Adiponectin (also known as 30-kDa adipocyte complement-related protein or Acrp30) is an abundant
adipocyte-derived plasma protein with anti-atherosclerotic and insulin-sensitizing properties.
In order to investigate the potential mechanism(s) of the vascular protective effect of ... Cited by 185 - Related articles - All 5 versions
