- ►shouxi.net CJ Groves, E Zeggini, M Walker, GA Hitman, JC … - Diabetes, 2006 - Am Diabetes Assoc Obesity is a major health problem, and many family-based studies have suggested
that it has a strong genetic basis. We performed a genome-wide quantitative
trait linkage scan for loci influencing BMI in 573 pedigrees from the UK We ... Cited by 11 - Related articles - BL Direct - All 5 versions
MM Swarbrick, B Waldenmaier, LA Pennacchio, … - Plos Biology, 2005 - biology.plosjournals.org The demonstration of association between common genetic variants and chronic
human diseases such as obesity could have profound implications for the
prediction, prevention, and treatment of these conditions. Unequivocal ... Cited by 38 - Related articles - Cached - BL Direct - All 13 versions
TW Boesgaard, SI Castella, G Andersen, A … - Diabetic Medicine, 2007 - interscience.wiley.com Aims The glutamate decarboxylase gene (GAD2) encodes GAD65, an enzyme catalysing
the production of the γ-aminobutyric acid (GABA) which interacts with
neuropeptide Y to stimulate food intake. It has been suggested that in ... Cited by 2 - Related articles - BL Direct - All 7 versions
SC Hunt, Y Xin, LL Wu, PN Hopkins, TD … - Obesity, 2006 - nature.com Three polymorphisms of the glutamate decarboxylase 2 gene, which encodes the
glutamic acid decarboxylase enzyme, have been associated with severe obesity in
a large French cohort. One of these polymorphisms was shown to have ... Cited by 5 - Related articles - All 3 versions
JV van Vliet-Ostaptchouk, MH Hofker, YT … - Obesity Reviews, 2009 - interscience.wiley.com We summarize current knowledge on the physiological role of the hypothalamus in
body-weight regulation and review genetic studies on the hypothalamic candidate
genes in relation to obesity. Together, data from functional and genetic ... Related articles
A Hinney, J Hebebrand - Obesity: Genomics and Postgenomics, 2007 - books.google.com Association and Linkage Studies in Caucasians Anke Hinney and Johannes Hebebrand
Department of Child and Adolescent Psychiatry, University of Duisburg-Essen,
Essen, Germany Polygenic effects are relevant in human body weight ... Related articles
S Canizales-Quinteros - Rev Endocrinol Nutr, 2008 - medigraphic.com La obesidad es una enfermedad crónica multifactorial de gran trascendencia
socio-sanitaria y económica, la cual constituye un serio problema de salud
pública a nivel mundial. En México, el aumento en la prevalencia de la ... Cited by 1 - Related articles - All 3 versions
- ►ajcn.org M Pichler, B Kollerits, IM Heid, SC Hunt, TD … - American Journal of Clinical Nutrition, 2008 - Am Soc Nutrition 2 Supported by the Genomics of Lipid-associated Disorders—GOLD of the Austrian
Genome Research Programme GEN-AU (to FK), the German National Genome Research
Net and a subcontract of the 1 R01 DK 075787-01A1 from the NIH/NIDDK (to ... Cited by 1 - Related articles - All 4 versions
U Jaakkola, J Kallio, RJ Heine, G Nijpels…, 2007 - nature.com The leucine7 to proline7 (Leu7Pro) polymorphism in preproneuropeptide Y
(preproNPY) has been associated with accelerated atherosclerosis and type II
diabetes, both of which are obesity-related diseases. The current study ... Cited by 1 - Related articles - All 4 versions
HJ Wang, AK Wermter, TT Nguyen, A Scherag, … - Hormone and metabolic research. Hormon-und …, 2007 - ncbi.nlm.nih.gov The neuropeptide Y2 receptor (NPY2R) has been implicated in body weight
regulation both in humans and rodents. We investigated if genetic variation in
the NPY2R gene is associated with obesity in German extremely obese ... Cited by 1 - Related articles - BL Direct - All 4 versions