- ►diabetesjournals.org JA Emamaullee, AM Shapiro - Diabetes, 2006 - Am Diabetes Assoc A substantial proportion of the transplanted islet mass fails to engraft due to
death by apoptosis, and a number of strategies have been explored to inhibit
β-cell loss. Inhibition of extrinsic signals of apoptosis (ie, cFLIP or ... Cited by 31 - Related articles - BL Direct - All 10 versions
I Transplantation - Diabetes, 2006 - Am Diabetes Assoc A substantial proportion of the transplanted islet mass fails to engraft due to
death by apoptosis, and a number of strategies have been explored to inhibit
-cell loss. Inhibi- tion of extrinsic signals of apoptosis (ie, cFLIP or ... Related articles
JA Emamaullee, RV Rajotte, P Liston, RG … - Diabetes, 2005 - Am Diabetes Assoc The Edmonton Protocol for treatment of type 1 diabetes requires islets from two
or more donors to achieve euglycemia in a single recipient, primarily because
soon after portal infusion, the majority of the transplanted cells undergo ... Cited by 24 - Related articles - BL Direct - All 8 versions
Z Yang, M Chen, JD Ellett, JD Carter, KL … - American Journal of Transplantation, 2005 - diakine.com The pathogenesis of pancreatic b -cell death in diabetes mellitus is still under
investigation. Inflammation is likely to be one of the factors responsible for b
-cell death during disease development. In this study, we have used a novel ... Cited by 27 - Related articles - View as HTML - All 6 versions
P Fiorina, A Vergani, A Petrelli, F D'Addio, L … - Diabetes Care, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—We measured several metabolic and immunological
markers at the time of pretransplant and several time points posttransplantation
in 17 patients with long-term functioning graft (long fx) and 20 patients ... Cited by 6 - Related articles - BL Direct - All 4 versions
J Tjernberg, KN Ekdahl, JD Lambris, O … - Transplantation, 2008 - pubmedcentral.nih.gov Clinical islet transplantation is associated with loss of transplanted islets
necessitating tissue from more than one donor to obtain insulin independence.
The instant blood-mediated inflammatory reaction (IBMIR) is one explanation ... Cited by 7 - Related articles - BL Direct - All 5 versions
MA Naftanel, DM Harlan - PLoS Medicine, 2004 - pubmedcentral.nih.gov Treatment for, and the prognosis of, type-1 diabetes mellitus (T1DM) has
progressed dramatically during the last century, but the disease remains a major
cause of morbidity and mortality. Although precise figures are not ... Cited by 23 - Related articles - BL Direct - All 8 versions
L Dolezalova, M Vrana, M Dobrovolna, M … - Neoplasma, 2002 - ncbi.nlm.nih.gov The selection of human leukocyte antigen (HLA) compatible unrelated donors for
hematopoietic stem cell transplantation (HSCT) is based on the direct genotyping
of HLA class I and class II alleles (HLA-A, -B, -C, -DRB1, -DQB1 loci). The ... Cited by 10 - Related articles - BL Direct
TB Mysore, TA Shinkel, J Collins, EJ Salvaris … - Diabetes, 2005 - Am Diabetes Assoc Primary nonfunction of transplanted islets results in part from their
sensitivity to reactive oxygen species (ROS) generated during the isolation and
transplantation process. Our aim was to examine whether coexpression of ... Cited by 27 - Related articles - All 5 versions
G Maleux, P Gillard, B Keymeulen, D Pipeleers … - Journal of Vascular and Interventional Radiology, 2005 - Elsevier Between December 2001 and November 2003, 15 patients with C-peptide–negative
type 1 diabetes underwent 31 percutaneous injections for intraportal
implantation of β-cell grafts. Grafts consisted of cultured β-cell ... Cited by 14 - Related articles - BL Direct - All 19 versions
