- ►diabetesjournals.org D Zelent, ML Golson, B Koeberlein, R Quintens, L Van … - Diabetes, 2006 - Am Diabetes Assoc Enzymatic activity of glucokinase was demonstrated, quantitated, and characterized kinetically
in rat and mouse pituitary extracts using a highly specific and sensitive spectrometric assay. A
previously proposed hypothesis that the glucokinase gene might be expressed in the ... Cited by 19 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org JV Sagen, S Odili, L Bjørkhaug, D Zelent, C Buettger, J … - Diabetes, 2006 - Am Diabetes Assoc Glucokinase functions as a glucose sensor in pancreatic β-cells and regulates hepatic glucose
metabolism. A total of 83 probands were referred for a diagnostic screening of mutations in the
glucokinase (GCK) gene. We found 11 different mutations (V62A, G72R, L146R, A208T, ... Cited by 20 - Related articles - BL Direct - All 5 versions
S Baltrusch, S Lenzen, DA Okar, AJ Lange, M … - Journal of Biological …, 2001 - ASBMB The low affinity glucose-phosphorylating enzyme glucokinase shows the phenomenon of intracellular
translocation in beta cells of the pancreas and the liver. To identify potential binding partners
of glucokinase by a systematic strategy, human beta cell glucokinase was screened by a ... Cited by 5 - Related articles - All 2 versions
- ►jbc.org VV Heredia, TJ Carlson, E Garcia, S Sun - Journal of Biological Chemistry, 2006 - ASBMB Glucokinase (GK) has several known polymorphic activating mutations that increase the enzyme
activity by enhancing glucose binding affinity and/or by alleviating the inhibition of glucokinase
regulatory protein (GKRP), a key regulator of GK activity in the liver. Kinetic studies were ... Cited by 13 - Related articles - All 6 versions
- ►jhc.org RL Sorenson, LE Stout, TC Brelje, TL Jetton, … - … of Histochemistry and …, 2007 - Histochemical Soc PITUITARY HORMONES exert extensive and profound influences on fuel homeostasis, energy
metabolism, growth, and reproduction of the organism. The regulation of synthesis and secretion
of these hormones is widely accepted to be organized at three levels (Norman and ... Cited by 7 - Related articles - BL Direct - All 5 versions
[CITATION] Interaction of PFK-2/FBPase-2 with glucokinase activated glucose phosphorylation …
M Caüzac, C Kohl, J Girard, JP Pégorier - Biochemical pharmacology, 2005 - Elsevier S-15261 is a new oral anti-hyperglycemic agent that increases insulin sensitivity in various
insulin-resistant animal models. The aim of this study was to determine the short- and long-term
effects of S-15261 and its metabolites (S–15511 and Y-415) on fatty acid and glucose ... Cited by 6 - Related articles - All 3 versions
- ►endojournals.org S Baltrusch, S Langer, L Massa, M Tiedge, S Lenzen - Endocrinology, 2006 - Endocrine Soc The glucose sensor enzyme glucokinase plays a pivotal role in the regulation of glucose-induced
insulin secretion in pancreatic ß-cells. Activation of glucokinase represents a promising concept
for the treatment of type 2 diabetes. Therefore, we analyzed the glucokinase activation ... Cited by 8 - Related articles - BL Direct - All 4 versions
[CITATION] Electron microscopic demonstration of glucokinase in insulin granules of rat …
