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Scholar Results 1 - 10 of about 101 related to Biddinger: Leptin Suppresses Stearoyl-CoA Desaturase 1 by Mechanisms Independent of Insulin.... (0.11 sec) 

Leptin Suppresses Stearoyl-CoA Desaturase 1 by Mechanisms Independent of …


SB Biddinger, M Miyazaki, J Boucher, JM Ntambi, CR … - Diabetes, 2006 - Am Diabetes Assoc
Stearoyl-CoA desaturase (SCD)1 catalyzes the rate-limiting reaction of monounsaturated fatty
acid (MUFA) synthesis and plays an important role in the development of obesity. SCD1 is suppressed
by leptin but induced by insulin. We have used animal models to dissect the effects of ...
Cited by 18 - Related articles - BL Direct - All 5 versions

[CITATION] William-Olsson


D Linden - L., Ahnmark, A., Ekroos, K., Hallberg, C., Sjogren, HP, …, 2006
Cited by 2 - Related articles

The expression and the significance of L-FABP and FATP4 in the development of …


AJ Feng, DF Chen - Zhonghua gan zang bing za zhi= Zhonghua …, 2005 - ncbi.nlm.nih.gov
OBJECTIVE: To study the effect of liver fatty acid binding protein(L-FABP) and fatty acid transport
protein (FATP4) in the development of nonalcoholic fatty liver disease (NAFLD) in rats.
METHODS: The expression of L-FABP and FATP4 genes was examined in fatty liver rats ...
Cited by 2 - Related articles - BL Direct

[CITATION] BROWSE, J., and MILLER, MA (2006). Oocyte signals derived from …


HM Kubagawa, JL Watts, C Corrigan, JW Edmonds, E … - Nat Cell Biol
Cited by 4 - Related articles

High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin …


SE Cohen, E Kokkotou, SB Biddinger, T Kondo, R … - Journal of Biological …, 2007 - ASBMB
Liver-specific insulin receptor knock-out (LIRKO) mice display hyperinsulinemia, abnormal glucose
metabolism, and progressive liver dysfunction. In addition, circulating leptin levels appear to
be increased more than 10-fold. However, food intake, body weight, and adipose mass ...
Cited by 18 - Related articles - All 5 versions

Polyunsaturated fatty acids influence synaptojanin localization to regulate synaptic …

- molbiolcell.org
E Marza, T Long, A Saiardi, M Sumakovic, S … - Molecular biology of …, 2008 - Am Soc Cell Biol
The lipid polyunsaturated fatty acids are highly enriched in synaptic membranes, including synaptic
vesicles, but their precise function there is unknown. Caenorhabditis elegans fat-3 mutants lack
long-chain polyunsaturated fatty acids (LC-PUFAs); they release abnormally low levels of ...
Cited by 7 - Related articles - All 8 versions

Probing the role of stearoyl-CoA desaturase–1 in hepatic insulin resistance

- nih.gov [PDF] 
MT Flowers, M Miyazaki, X Liu, JM … - Journal of Clinical …, 2006 - Am Soc Clin Investig
Previous studies using stearoyl-CoA desaturase–1–deficient (SCD1-deficient) mice have shown
that this enzyme plays an important role in many diseases of altered cellular metabolism including
obesity, insulin resistance, and dyslipidemia. Although SCD1 activity is highest in ...
Cited by 19 - Related articles - BL Direct - All 8 versions

Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated …


M Miyazaki, A Dobrzyn, WC Man, K Chu, H … - Journal of Biological …, 2004 - ASBMB
Stearoyl-CoA desaturase (SCD) synthesizes oleate necessary for the biosynthesis of triglycerides
and other lipids. Mice with a targeted disruption of the SCD1 gene are deficient in tissue oleate
and have reduced expression of the sterol regulatory element-binding protein (SREBP) ...
Cited by 72 - Related articles - BL Direct - All 6 versions

An explicit test of the phospholipid saturation hypothesis of acquired cold tolerance …


P Murray, SAL Hayward, GG Govan, AY … - Proceedings of the …, 2007 - National Acad Sciences
Protection of poikilothermic animals from seasonal cold is widely regarded as being causally
linked to changes in the unsaturation of membrane phospholipids, yet in animals this proposition
remains formally untested. We have now achieved this by the genetic manipulation of ...
Cited by 9 - Related articles - BL Direct - All 6 versions

Quantitative trait loci for individual adipose depot weights in C57BL/6ByJ x 129P3/ …

- nih.gov [PDF] 
DR Reed, AH McDaniel, X Li, MG Tordoff, AA … - Mammalian Genome, 2006 - Springer
Page 1. Quantitative trait loci for individual adipose depot weights in C57BL/6ByJ
x 129P3/JF 2 mice Danielle R. Reed, Amanda H. McDaniel, Xia Li, Michael G. Tordoff,
Alexander A. Bachmanov Monell Chemical Senses Center ...
Cited by 11 - Related articles - BL Direct - All 6 versions


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