SB Biddinger, M Miyazaki, J Boucher, JM Ntambi, CR … - Diabetes, 2006 - Am Diabetes Assoc Stearoyl-CoA desaturase (SCD)1 catalyzes the rate-limiting reaction of monounsaturated fatty
acid (MUFA) synthesis and plays an important role in the development of obesity. SCD1 is suppressed
by leptin but induced by insulin. We have used animal models to dissect the effects of ... Cited by 18 - Related articles - BL Direct - All 5 versions
[CITATION] William-Olsson
D Linden - L., Ahnmark, A., Ekroos, K., Hallberg, C., Sjogren, HP, …, 2006 Cited by 2 - Related articles
AJ Feng, DF Chen - Zhonghua gan zang bing za zhi= Zhonghua …, 2005 - ncbi.nlm.nih.gov OBJECTIVE: To study the effect of liver fatty acid binding protein(L-FABP) and fatty acid transport
protein (FATP4) in the development of nonalcoholic fatty liver disease (NAFLD) in rats.
METHODS: The expression of L-FABP and FATP4 genes was examined in fatty liver rats ... Cited by 2 - Related articles - BL Direct
[CITATION] BROWSE, J., and MILLER, MA (2006). Oocyte signals derived from …
SE Cohen, E Kokkotou, SB Biddinger, T Kondo, R … - Journal of Biological …, 2007 - ASBMB Liver-specific insulin receptor knock-out (LIRKO) mice display hyperinsulinemia, abnormal glucose
metabolism, and progressive liver dysfunction. In addition, circulating leptin levels appear to
be increased more than 10-fold. However, food intake, body weight, and adipose mass ... Cited by 18 - Related articles - All 5 versions
- ►molbiolcell.org E Marza, T Long, A Saiardi, M Sumakovic, S … - Molecular biology of …, 2008 - Am Soc Cell Biol The lipid polyunsaturated fatty acids are highly enriched in synaptic membranes, including synaptic
vesicles, but their precise function there is unknown. Caenorhabditis elegans fat-3 mutants lack
long-chain polyunsaturated fatty acids (LC-PUFAs); they release abnormally low levels of ... Cited by 7 - Related articles - All 8 versions
- ►nih.gov [PDF] MT Flowers, M Miyazaki, X Liu, JM … - Journal of Clinical …, 2006 - Am Soc Clin Investig Previous studies using stearoyl-CoA desaturase–1–deficient (SCD1-deficient) mice have shown
that this enzyme plays an important role in many diseases of altered cellular metabolism including
obesity, insulin resistance, and dyslipidemia. Although SCD1 activity is highest in ... Cited by 19 - Related articles - BL Direct - All 8 versions
M Miyazaki, A Dobrzyn, WC Man, K Chu, H … - Journal of Biological …, 2004 - ASBMB Stearoyl-CoA desaturase (SCD) synthesizes oleate necessary for the biosynthesis of triglycerides
and other lipids. Mice with a targeted disruption of the SCD1 gene are deficient in tissue oleate
and have reduced expression of the sterol regulatory element-binding protein (SREBP) ... Cited by 72 - Related articles - BL Direct - All 6 versions
P Murray, SAL Hayward, GG Govan, AY … - Proceedings of the …, 2007 - National Acad Sciences Protection of poikilothermic animals from seasonal cold is widely regarded as being causally
linked to changes in the unsaturation of membrane phospholipids, yet in animals this proposition
remains formally untested. We have now achieved this by the genetic manipulation of ... Cited by 9 - Related articles - BL Direct - All 6 versions
- ►nih.gov [PDF] DR Reed, AH McDaniel, X Li, MG Tordoff, AA … - Mammalian Genome, 2006 - Springer Page 1. Quantitative trait loci for individual adipose depot weights in C57BL/6ByJ
x 129P3/JF 2 mice Danielle R. Reed, Amanda H. McDaniel, Xia Li, Michael G. Tordoff,
Alexander A. Bachmanov Monell Chemical Senses Center ... Cited by 11 - Related articles - BL Direct - All 6 versions