H Okazaki, M Igarashi, M Nishi, M Tajima, M … - Diabetes, 2006 - Am Diabetes Assoc Molecular mechanisms underlying lipolysis, as defined by mobilization of fatty
acids from adipose tissue, are not fully understood. A database search for
enzymes with α/β hydrolase folds, the GXSXG motif for serine esterase and ... Cited by 24 - Related articles - BL Direct - All 7 versions
KG Soni, R Lehner, P Metalnikov, P O' … - Journal of Biological Chemistry, 2004 - ASBMB Hydrolysis of triglycerides is central to energy homeostasis in white adipose
tissue (WAT). Hormone-sensitive lipase (HSL) was previously felt to mediate all
lipolysis in WAT. Surprisingly, HSL-deficient mice show active ... Cited by 71 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org EE Kershaw, JK Hamm, LAW Verhagen, O … - Diabetes, 2006 - Am Diabetes Assoc Adipose triglyceride lipase (ATGL) is a recently described adipose-enriched
protein with triglyceride-specific lipase activity. ATGL shares the greatest
sequence homology with adiponutrin, a nutritionally regulated protein of ... Cited by 77 - Related articles - BL Direct - All 6 versions
- ►bentham.org [PDF] R Birner-Gruenberger, A Hermetter - Current Drug Discovery Technologies, 2007 - ingentaconnect.com Abstract: Lipases play fundamental roles in biological processes since
hydrolysis of triacylglycerols and cholesteryl es- ters is a key event in energy
homeostasis of animals. Perturbations in the metabolism and the cellular ... Cited by 4 - Related articles - BL Direct - All 5 versions
- ►jbc.org V Subramanian, A Rothenberg, C Gomez, AW … - Journal of Biological Chemistry, 2004 - ASBMB Perilipins, the major structural proteins coating the surfaces of mature lipid
droplets of adipocytes, play an important role in the regulation of
triacylglycerol storage and hydrolysis. We have used proteomic analysis to ... Cited by 65 - Related articles - BL Direct - All 4 versions
- ►aspetjournals.org TH Claus, DB Lowe, Y Liang, AI Salhanick, CK … - Journal of Pharmacology and Experimental …, 2005 - ASPET Elevation of plasma free fatty acids has been linked with insulin resistance and
diabetes. Inhibition of lipolysis may provide a mechanism to decrease plasma
fatty acids, thereby improving insulin sensitivity. Hormone-sensitive ... Cited by 16 - Related articles - BL Direct - All 5 versions
H Susani-Etzerodt, H Schmidinger, G … - Chemistry and physics of lipids, 2006 - Elsevier This work describes the synthesis of a library of fluorescent and/or
biotinylated alkylphosphonate inhibitors being reactive towards serine
hydrolases, especially lipases and esterases. Fluorescent inhibitors can be ... Cited by 7 - Related articles - All 4 versions
J Berndt, S Kralisch, N Klöting, K Ruschke, … - Experimental and clinical endocrinology & diabetes: …, 2008 - ncbi.nlm.nih.gov 1: Exp Clin Endocrinol Diabetes. 2008 Apr;116(4):203-10. Epub 2007 Dec 10. Adipose
triglyceride lipase gene expression in human visceral obesity. ... Cited by 8 - Related articles - BL Direct - All 3 versions
T Yamaguchi, N Omatsu, S Matsushita, T … - Journal of Biological Chemistry, 2004 - ASBMB Lipid droplets (LDs) are a class of ubiquitous cellular organelles that are
involved in lipid storage and metabolism. Although the mechanisms of the
biogenesis of LDs are still unclear, a set of proteins called the PAT ... Cited by 67 - Related articles - BL Direct - All 4 versions
AK Ghosh, G Ramakrishnan, C … - Journal of Biological Chemistry, 2008 - ASBMB The most abundant form of energy is stored as triacylglycerol (TAG) 3 in the
lipid droplets (LDs) or adiposomes. LDs also have a high concentration of
cholesterol esters, enclosed within the coat of proteins bound to ... Cited by 21 - Related articles - All 8 versions
