- ►diabetesjournals.org J Wysocki, M Ye, MJ Soler, SB Gurley, HD … - Diabetes, 2006 - Am Diabetes Assoc ACE-related carboxypeptidase (ACE2) may counterbalance the angiotensin (ANG)
II–promoting effects of ACE in tissues where both enzymes are found.
Alterations in renal ACE and ACE2 expression have been described in ... Cited by 60 - Related articles - BL Direct - All 7 versions
- ►asnjournals.org M Ye, J Wysocki, J William, MJ Soler, I Cokic, … - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol Angiotensin-converting enzyme 2 (ACE2) expression has been shown to be altered
in renal tubules from diabetic mice. This study examined the localization of ACE
and ACE2 within the glomerulus of kidneys from control (db/m) and diabetic ... Cited by 60 - Related articles - BL Direct - All 6 versions
- ►amjpathol.org GY Oudit, AM Herzenberg, Z Kassiri, D Wong … - American Journal of Pathology, 2006 - ASIP Angiotensin-converting enzyme-2 (ACE2), a membrane-bound carboxymonopeptidase
highly expressed in the kidney, functions as a negative regulator of the
renin-angiotensin system. Here we report early accumulation of fibrillar ... Cited by 69 - Related articles - BL Direct - All 7 versions
MJ Soler, J Wysocki, M Ye, J Lloveras, Y … - Kidney International, 2007 - nature.com Angiotensin converting enzyme 2 (ACE2) is localized to the glomerular epithelial
cells. Since ACE2 promotes the degradation of angiotensin II, a decrease in ACE2
activity could lead to the development of glomerular injury. We gave a ... Cited by 30 - Related articles - BL Direct - All 3 versions
Z Su, J Zimpelmann, KD Burns - Kidney international, 2006 - nature.com Angiotensin-converting enzyme 2 (ACE2) is a homolog of ACE, which is not blocked
by ACE inhibitors. High amounts of ACE2 are present in the proximal tubule, and
ACE2 catalyzes generation of angiotensin 1–7 (Ang-(1–7)) by this ... Cited by 51 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org M Ye, J Wysocki, P Naaz, MR Salabat, MS … - Hypertension, 2004 - Am Heart Assoc Unlike the ubiquitous angiotensin-converting enzyme (ACE), the ACE-related
carboxypeptidase 2 (ACE 2) is predominantly expressed in the heart, kidney, and
testis. ACE 2 degrades angiotensin (Ang) II to Ang (1–7) and Ang I to Ang ... Cited by 95 - Related articles - BL Direct - All 9 versions
- ►nih.gov SB Gurley, A Allred, TH Le, R Griffiths, L … - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig The carboxypeptidase ACE2 is a homologue of angiotensin-converting enzyme (ACE).
To clarify the physiological roles of ACE2, we generated mice with targeted
disruption of the Ace2 gene. ACE2-deficient mice were viable, fertile, and ... Cited by 76 - Related articles - BL Direct - All 13 versions
- ►physiology.org [PDF] N Li, J Zimpelmann, K Cheng, JA Wilkins, KD … - American Journal of Physiology- Renal Physiology, 2005 - Am Physiological Soc 31 articles, 19 of which you can access free at: This article cites
http://ajprenal.physiology.org/cgi/content/full/288/2/F353#BIBL ... 24 other
HighWire hosted articles, the first 5 are: This article has been cited by Cited by 78 - Related articles - All 5 versions
AT Lely, I Hamming, H Van Goor, GJ Navis - The Journal of Pathology, 2004 - ingentaconnect.com AT Lely, 1 * I Hamming, 2 H van Goor 2 and GJ Navis 1 ... 1 Department of
Nephrology, Groningen University Medical Centre, The Netherlands 2 Department of
Pathology and Laboratory Medicine, Groningen University Medical Centre, The ... Cited by 63 - Related articles - BL Direct - All 4 versions
- ►amjpathol.org DW Wong, GY Oudit, H Reich, Z Kassiri, J … - American Journal of Pathology, 2007 - ASIP Activation of the renin-angiotensin system (RAS) and the generation of
angiotensin (Ang) II play an important role in the pathogenesis of diabetic
nephropathy and blockade of the RAS in both experimental and clinical ... Cited by 37 - Related articles - BL Direct - All 8 versions
