HC Freeman, A Hugill, NT Dear, FM Ashcroft, … - Diabetes, 2006 - Am Diabetes Assoc The C57BL/6J mouse displays glucose intolerance and reduced insulin secretion.
The genetic locus underlying this phenotype was mapped to nicotinamide
nucleotide transhydrogenase (Nnt) on mouse chromosome 13, a nuclear-encoded ... Related articles - All 2 versions
- ►eurodiabesity.org [PDF] HC Freeman, A Hugill, NT Dear, FM Ashcroft, … - Diabetes, 2006 - Am Diabetes Assoc The C57BL/6J mouse displays glucose intolerance and reduced insulin secretion.
The genetic locus underlying this phenotype was mapped to nicotinamide
nucleotide transhydrogenase (Nnt) on mouse chromosome 13, a nu- ... Related articles - All 3 versions
NB Pestov, MI Shakhparonov - Russian Journal of Bioorganic Chemistry, 2009 - Springer Transhydrogenase is an integral membrane protein. Its molecular weight is
100–110 kDa [1].2 The amino acid sequences of transhydrogenases from various
spe- cies are very conservative. For example, the transhy- drogenases of ... Related articles
T Kayo, H Fujita, J Nozaki… - Comparative medicine, 2000 - ncbi.nlm.nih.gov BACKGROUND AND PURPOSE: Our objective was to map the genes responsible for poor
glucose tolerance in a C57BL/6 (B6) mouse model, which provides a human model of
non-insulin-dependent diabetes mellitus. Insulin secretion was found to be ... Cited by 16 - Related articles - BL Direct
- ►endocrinology-journals.org M Fex, N Wierup, MD Nitert, M Ristow, H … - Journal of Endocrinology, 2007 - Soc Endocrinology Gene inactivation, using the Cre/LoxP system, is an essential technique in
tissue-specific gene targeting. The rat insulin promoter 2-Cre recombinase
(RIP2-Cre) mouse (also called RIP-Cre or B6.Cg-Tg (Ins2-cre) 25 Mgn/J, ... Cited by 3 - Related articles - BL Direct - All 2 versions
H Freeman, K Shimomura, RD Cox, FM … - Biochemical Society Transactions, 2006 - biochemsoctrans.cn Abstract This paper reviews recent studies on the role of Nnt (nicotinamide
nucleotide transhydrogenase) in insulin secretion and detoxification of ROS
(reactive oxygen species). Glucose-stimulated insulin release from ... Cited by 10 - Related articles - View as HTML - BL Direct - All 5 versions
- ►oxfordjournals.org TT Huang, M Naeemuddin, S Elchuri, M … - Human Molecular Genetics, 2006 - Oxford Univ Press Sod2–/– mice, which are deficient in the mitochondrial form of superoxide
dismutase (MnSOD), have a short survival time that is strongly affected by
genetic background. This suggests the existence of genetic modifiers that ... Cited by 20 - Related articles - BL Direct - All 7 versions
- ►psu.edu [PDF] R Bertram, M Gram Pedersen, DS Luciani, A … - Journal of theoretical biology, 2006 - Elsevier Most of the adenosine triphosphate (ATP) synthesized during glucose metabolism
is produced in the mitochondria through oxidative phosphorylation. This is a
complex reaction powered by the proton gradient across the mitochondrial ... Cited by 14 - Related articles - All 8 versions
