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Scholar Results 1 - 10 of about 101 related to Schmelzle: Temporal dynamics of tyrosine phosphorylation in insulin signaling. (0.14 sec) 

Temporal dynamics of tyrosine phosphorylation in insulin signaling

- shouxi.net
K Schmelzle, S Kane, S Gridley, GE Lienhard … - Diabetes, 2006 - Am Diabetes Assoc
The insulin-signaling network regulates blood glucose levels, controls
metabolism, and when dysregulated, may lead to the development of type 2
diabetes. Although the role of tyrosine phosphorylation in this network is ...
Cited by 44 - Related articles - BL Direct - All 5 versions

[PDF] Temporal Dynamics of Tyrosine Phosphorylation in Insulin Signaling


FM White - mit.edu
Katrin Schmelzle #, Susan Kane§, Scott Gridley§, Gustav E. Lienhard§, and
Forest M. White#* #Biological Engineering Division, MIT, Cambridge MA 02139;
§Biochemistry Department, Dartmouth Medical School, Hanover NH 03755
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Quantitative proteomic assessment of very early cellular signaling events


J Dengjel, V Akimov, JV Olsen, J Bunkenborg … - Nature biotechnology, 2007 - nature.com
Technical limitations have prevented proteomic analyses of events occurring less
than 30 s after signal initiation. We developed an automated, continuous
quench-flow system allowing quantitative proteomic assessment of very early ...
Cited by 33 - Related articles - BL Direct - All 5 versions

Quantitative proteomic approaches for studying phosphotyrosine signaling


SJ Ding, WJ Qian, RD Smith - Expert Review of Proteomics, 2007 - ingentaconnect.com
† Author for correspondence Pacific Northwest National Laboratory, Biological
Science Division & Environmental Molecular Sciences Laboratory, PO Box 999,
MSIN: K8-98, Richland, WA 99352, USA Tel.: +1 509 376 0723 Fax: +1 509 376 ...
Cited by 10 - Related articles - BL Direct - All 5 versions

The stimulus-induced tyrosine phosphorylation of Munc18c facilitates vesicle exocytosis

- jbc.org
E Oh, DC Thurmond - Journal of Biological Chemistry, 2006 - ASBMB
Stimulus-induced tyrosine phosphorylation of Munc18c was investigated as a
potential regulatory mechanism by which the Munc18c-Syntaxin 4 complex can be
dissociated in response to divergent stimuli in multiple cell types. Use of ...
Cited by 21 - Related articles - BL Direct - All 6 versions

Modeling HER2 effects on cell behavior from mass spectrometry phosphotyrosine data


N Kumar, A Wolf-Yadlin, FM White, DA … - PLoS Comput Biol, 2007 - compbiol.plosjournals.org
Cellular behavior in response to stimulatory cues is governed by information
encoded within a complex intracellular signaling network. An understanding of
how phenotype is determined requires the distributed characterization of ...
Cited by 35 - Related articles - Cached - All 9 versions

Phosphoproteomic analysis of Her2/neu signaling and inhibition

- nih.gov
R Bose, H Molina, AS Patterson, JK Bitok, B … - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences
Her2/neu (Her2) is a tyrosine kinase belonging to the EGF receptor (EGFR)/ErbB
family and is overexpressed in 20–30% of human breast cancers. We sought to
characterize Her2 signal transduction pathways further by using MS-based ...
Cited by 55 - Related articles - BL Direct - All 11 versions

Quantitative phosphotyrosine proteomics of EphB2 signaling by stable isotope labeling with …

- nih.gov
G Zhang, DS Spellman, EY Skolnik, TA … - J. Proteome Res, 2006 - pubs.acs.org
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... These authors contributed equally to this work.
Cited by 37 - Related articles - All 5 versions

Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling …

- nih.gov
A Wolf-Yadlin, S Hautaniemi, DA … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences
Although recent developments in MS have enabled the identification and
quantification of hundreds of phosphorylation sites from a given biological
sample, phosphoproteome analysis by MS has been plagued by inconsistent ...
Cited by 97 - Related articles - BL Direct - All 10 versions

Effects of HER2 overexpression on cell signaling networks governing proliferation and …

- nih.gov
A Wolf-Yadlin, N Kumar, Y Zhang, S … - Molecular Systems Biology, 2006 - nature.com
Mass spectrometry was used to identify and quantify hundreds of tyrosine
phosphorylation sites from human mammary epithelial cells stimulated with EGF or
HRG in the presence or absence of HER2 over-expression.
Cited by 75 - Related articles - All 11 versions


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