S Costes, C Broca, G Bertrand, AD Lajoix, D Bataille, J … - diabetes, 2006 - Am Diabetes Assoc Glucose utilization and oxidation within the pancreatic ß-cells lead to ATP production and subsequent
closure of the ATP-dependent potassium channel, eliciting the entry of calcium through the opening
of L-type voltage-dependent calcium channels (1–3). The calcium entry induced by ... Cited by 23 - Related articles - BL Direct - All 4 versions
S Costes, C Broca, G Bertrand, AD Lajoix, D Bataille, J … - Diabetes, 2006 - Am Diabetes Assoc Page 1. Original Article ERK1/2 Control Phosphorylation and Protein Level of
cAMP-Responsive Element–Binding Protein A Key Role in Glucose-Mediated
Pancreatic -Cell Survival Safia Costes, 1 Christophe Broca, 1 Gyslaine ... Related articles
S Costes, C Broca, G Bertrand, AD Lajoix, D Bataille, J … - 糖尿病学杂志, 2006 - journal.shouxi.net Glucose utilization and oxidation within the pancreatic -cells lead to ATP production and subsequent
closure of the ATP-dependent potassium channel, eliciting the entry of calcium through the opening
of L-type voltage-dependent calcium channels (1 3). The calcium entry induced by ... Related articles - Cached
S Mohanty, GA Spinas, K Maedler, RA Zuellig, R … - Experimental cell …, 2005 - Elsevier Studies in vivo indicate that IRS2 plays an important role in maintaining functional β-cell
mass. To investigate if IRS2 autonomously affects β-cells, we have studied proliferation,
apoptosis, and β-cell function in isolated rat and human islets after overexpression of ... Cited by 20 - Related articles - All 3 versions
S Dalle, C Longuet, S Costes, C Broca, O Faruque, … - Journal of Biological …, 2004 - ASBMB By using the MIN6 cell line and pancreatic islets, we show that in the presence of a low glucose
concentration, corresponding to physiological glucagon release from cells, glucagon treatment
of the cell caused a rapid, time-dependent phosphorylation and activation of p44/p42 ... Cited by 34 - Related articles - BL Direct - All 3 versions
- ►endojournals.org C Longuet, C Broca, S Costes, EH Hani, D Bataille, S … - Endocrinology, 2005 - Endocrine Soc The p44/p42 MAPKs (ERK1/2) cascade regulates ß-cell nuclear events, which modulates cell
differentiation and gene transcription, whereas its implication in processes occurring in the
cytoplasm, such as activation of the exocytotic machinery, is still unclear. Using the MIN6 ... Cited by 18 - Related articles - All 7 versions
- ►diabetesjournals.org I Briaud, MK Lingohr, LM Dickson, CE Wrede, CJ … - Diabetes, 2003 - Am Diabetes Assoc Glucose can activate the mitogen-activated kinases, Erk-1/2, and the ribosomal-S6 kinase, p70
S6K , in β-cells, contributing to an increase in mitogenesis. However, the signaling mechanism
by which glucose induces Erk-1/2 and p70 S6K phosphorylation activation is undefined. ... Cited by 78 - Related articles - BL Direct - All 4 versions
J Trümper, D Ross, H Jahr, MD Brendel, R Göke, D … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Glucose and glucagon-like peptide-1 have been shown to activate
extracellular signal- regulated kinase (ERK) and phosphoinositide 3-kinase in beta cells. We
examined the contributions of the small GTPases Rap and Ras and the serine–threonine ... Cited by 13 - Related articles - BL Direct - All 3 versions
M Scrima, P Campiglia, C Esposito, I Gomez- … - … and Biophysical Research …, 2007 - Elsevier Obestatin and its derivative Ob(11–23) are recently discovered peptides produced in the rat
stomach. They have proven to be involved in the regulation of energy balance, inhibiting
feeding, causing reductions in food intake, body weight and jejunal contraction in rodents. ... Cited by 4 - Related articles - All 3 versions
S Costes, C Longuet, C Broca, O Faruque, EH … - Ann NY Acad …, 2004 - interscience.wiley.com Abstract: Long-term hyperglycemia, a major characteristic of the diabetic state, contributes to
the deterioration of the β cell function, a concept known as β cell glucotoxicity. We used the MIN6
β cell line and isolated rat islets to clarify the signaling mechanism(s) used by glucose to ... Cited by 4 - Related articles - All 5 versions
